Novel Insight into Microcirculation and Microvascular Diseases
A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Pathology, Diagnostics, and Therapeutics".
Deadline for manuscript submissions: closed (30 November 2024) | Viewed by 3582
Special Issue Editor
Interests: proteomics; ageing; obesity; cardiometabolic syndrome
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Microcirculation represents an entity that comprises the terminal vascular network including arterioles, capillaries, venules, and initial lymphatic vessels. Microcirculation maintains tissue health and function by regulating blood flow, oxygen delivery, and nutrient exchange. Pathological changes in the microcirculation, or microangiopathy, play a pivotal role in end-organ dysfunction and diseases previously thought to be caused by macrocirculatory abnormalities. Disturbances of microvascular function precede macrovascular damage. Microcirculatory dysfunction is recognized as the earliest manifestations of cardiovascular, metabolic, and neurodegenerative diseases. Despite its importance, microcirculatory dysfunction is often overlooked in clinical practice due to limitations in available diagnostic tools. However, recent advances in imaging and analytical techniques have shed new light on the structure and function of small vessels, revealing the key role of microcirculation in the pathogenesis of various diseases.
In this Special Issue, we aim to explore the molecular and cellular mechanisms underlying microcirculatory dysfunction and its contribution to the development and progression of cardiovascular, metabolic, and neurodegenerative diseases. We will also discuss the latest diagnostic modalities and potential therapeutic strategies aimed at improving microvascular function. By bringing together experts from diverse fields, we hope to provide novel insights into the complex interplay between microcirculation and disease, and stimulate further research in this exciting and rapidly evolving field.
Prof. Dr. Yu Wang
Guest Editor
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Keywords
- microcirculation
- microangiopathy
- vascular health
- endothelial cells
- resistance arteries
- small vessels
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