Recent Applications of PLGA-Based Nanoparticles in Drug Delivery
A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Pharmacology".
Deadline for manuscript submissions: closed (31 March 2023) | Viewed by 6912
Special Issue Editor
Interests: colloids; self-assembly; drug-delivery; thin films; serum albumin; kynurenic acid; PLGA; atomic force microscopy; isotherm titration calorimetry
Special Issue Information
Dear Colleagues,
The new drug delivery strategies provide major advances over conventional medicine in the delivery of different drugs in a controlled and targeted manner with enhanced bioavailability and thus reduced side effects. Among the different polymer-based drug delivery systems, poly (lactic-co-glycolic acid) (PLGA), the synthetic block copolymer of lactic acid and glycolic acid, is one of the leading carriers in modern biomedical investigations both in local, long-term, and targeted drug delivery. Their popularity arises from their favorable physicochemical properties, their versatility towards modification, their biocompatibility, and their ability to improve the distribution and bioavailability of pharmaceutics. PLGA also plays an important role in the development of controlled and targeted drug delivery systems in the form of nanoparticles, microcapsules, and matrices. However, there are some drawbacks in the application of PLGA such as its low encapsulation efficiency and limited release of certain drugs.
The Special Issue aims to present novel PLGA-based treatment strategies, including encapsulation and transport of pharmaceuticals, in the treatment of various diseases and disorders. Topics may also include any aspects of the design, characterization, and functionalization of PLGA-containing delivery systems. State-of-the-art research on promising systems with both in vitro and in vivo analysis and controlled release with potential pre-clinical application is also welcome. We are looking forward to receiving manuscripts focused on the most recent advances in the field of PLGA-based drug delivery systems.
Dr. Viktória Varga
Guest Editor
Manuscript Submission Information
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Keywords
- PLGA
- poly (lactic-co-glycolic acid)
- drug delivery
- encapsulation
- sustained release
- targeted therapy
