Mechanisms of Metastasis in Pancreatic Cancer
A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Oncology".
Deadline for manuscript submissions: closed (31 January 2021) | Viewed by 2456
Special Issue Editor
Special Issue Information
Dear Colleagues,
Pancreatic ductal adenocarcinoma (PDAC) is a very aggressive disease with limited options in terms of effective therapies. The five-year survival rate for PDAC patients is estimated at 7%, making it the sixth most common cancer-related cause of death even though it is the twelfth in incidence. A major reason for this devastating outcome is the high metastatic rate of the disease combined with a lack of effective strategies for early detection and treatment of metastasis. Nearly 80% of the diagnosed patients have regional or distal metastasis. At autopsy, it was found that over 80% of PDAC patients have liver metastasis and nearly 45% have lung metastasis.
Preventing and/or treating PDAC metastasis will significantly improve the outcome of pancreatic cancer drugs. Therefore, understanding the mechanism of metastasis is crucial to overcome this burden. This Special Issue aims to develop novel insights to overcome PDAC metastasis. This includes novel concepts for the detection, prevention, and treatment of metastasis.
Dr. Mouad Edderkaoui
Guest Editor
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. International Journal of Molecular Sciences is an international peer-reviewed open access semimonthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. There is an Article Processing Charge (APC) for publication in this open access journal. For details about the APC please see here. Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
Keywords
- pancreatic cancer
- metastasis
- chemo-resistance
- drug development
- risk factors of cancer
