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Bio-Plasma for Molecular Science

A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Biophysics".

Deadline for manuscript submissions: closed (31 December 2023) | Viewed by 8750

Special Issue Editor

Prof. Dr. Ihn Han

E-Mail Website
Guest Editor
Plasma Bioscience Research Center, Applied Plasma Medicine Center, Department of Electrical & Biological Physics, Kwangwoon University, Seoul 01897, Republic of Korea
Interests: atmospheric pressure plasma; plasma-treated liquid; p53; MAPK pathway; oriental medicine; in silico drug screening
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues, 

Plasma Molecular Science is a multidisciplinary field of research that focuses on studies of the interaction of low-temperature plasmas with biological cells and tissues. Non‑thermal plasma technology has been considered as a new frontier in plasma medicine to treat cancers. Plasma technology is a relative newcomer to the field of medicines, food and agriculture, as well as cosmetics. Many experimental works conducted at several major universities, research centers, and companies around the world over the past decade determines that plasma can be used in a variety of medical applications as a plasma medicine. Recently, understanding of various mechanisms by which plasma can interact with biological systems, including effects of reactive nitrogen species, reactive oxygen species, and charges, has begun to emerge. Many advances took place in the last decade that promise to make cold plasma technology a basis for new medical therapies. However, many of the mechanisms by which non-thermal plasma affects cells and tissues remain interesting. For this Special Issue of the International Journal of Molecular Science, researchers active in all aspects of the field of plasma medicine are invited to submit their latest results. Papers covering fundamental studies, as well as papers discussing applications are welcome.

Prof. Dr. Ihn Han
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. International Journal of Molecular Sciences is an international peer-reviewed open access semimonthly journal published by MDPI.

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Keywords

  • nonthermal atmospheric plasma
  • plasma agriculture
  • plasma storage and packaging
  • plasma bioscience for cancer treatment
  • plasma cosmetic science

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Published Papers (3 papers)

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Research

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19 pages, 5547 KiB  
Article
Effect of Plasma-Treated Water with Magnesium and Zinc on Growth of Chinese Cabbage
by Rida Javed, Sohail Mumtaz, Eun Ha Choi and Ihn Han
Int. J. Mol. Sci. 2023, 24(9), 8426; https://doi.org/10.3390/ijms24098426 - 8 May 2023
Cited by 11 | Viewed by 2789
Abstract
Nonthermal biocompatible plasma (NBP) is an emerging technology in the field of agriculture to boost plant growth. Plasma is a source of various gaseous reactive oxygen and nitrogen species (RONS) and has a promising role in agricultural applications, as the long-lived RONS (H [...] Read more.
Nonthermal biocompatible plasma (NBP) is an emerging technology in the field of agriculture to boost plant growth. Plasma is a source of various gaseous reactive oxygen and nitrogen species (RONS) and has a promising role in agricultural applications, as the long-lived RONS (H2O2, NO2−, NO3−) in liquid activate signaling molecules in plant metabolism. Plasma-treated water (PTW) has an acidic pH of around 3 to 4, which may be detrimental to pH-sensitive plants. Innovative techniques for producing PTW with a pH value of 6 to 7 under neutral circumstances are desperately required to broaden the application range of NBP in agriculture. Furthermore, Pak Choi (Brassica campestris L.) is a Brassicaceae family green vegetable that has yet to be investigated for its response to NBP. In this work, we proposed an alternate method for neutralizing the pH of PTW by immersing metal ions (Mg2+ and Zn2+) in the PTW and observing its effect on Pak Choi. After synthesizing PTW with MECDBD, we analyzed germination rate and growth parameters, then seedlings for 42 days to show physiological, biochemical, and molecular levels. The germination rate was observed to be higher with PTW and more efficient when metal ions were present. Seedling length and germination rates were dramatically boosted when compared to DI water irrigation. Because of the increased chlorophyll and protein content, the plants responded to the availability of nitrogen by generating highly green leaves. Furthermore, we observed that PTW increases the expression of NR genes and GLR1 genes, which are further increased when metals are submerged in the PTW. Furthermore, PTW and PTW with metals reduced ABI5 and CHO1 which is associated with a growth inhibitor. According to this study, nonthermal plasma might be utilized to significantly improve seed germination and seedlings’ development. Full article
(This article belongs to the Special Issue Bio-Plasma for Molecular Science)
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10 pages, 2469 KiB  
Article
Characteristics of a Rollable Dielectric Barrier Discharge Plasma and Its Effects on Spinach-Seed Germination
by Jun Sup Lim, Daeun Kim, Sehoon Ki, Sohail Mumtaz, Abdul Munnaf Shaik, Ihn Han, Young June Hong, Gyungsoon Park and Eun Ha Choi
Int. J. Mol. Sci. 2023, 24(5), 4638; https://doi.org/10.3390/ijms24054638 - 27 Feb 2023
Cited by 17 | Viewed by 2610
Abstract
We investigated the characteristics of a rollable dielectric barrier discharge (RDBD) and evaluate its effects on seed germination rate and water uptake. The RDBD source was composed of a polyimide substrate and copper electrode, and it was mounted in a rolled-up structure for [...] Read more.
We investigated the characteristics of a rollable dielectric barrier discharge (RDBD) and evaluate its effects on seed germination rate and water uptake. The RDBD source was composed of a polyimide substrate and copper electrode, and it was mounted in a rolled-up structure for omnidirectional and uniform treatment of seeds with flowing synthetic air gas. The rotational and vibrational temperatures were measured to be 342 K and 2860 K, respectively, using optical emission spectroscopy. The chemical species analysis via Fourier-transform infrared spectroscopy and 0D chemical simulation showed that O3 production was dominant and NOx production was restrained at the given temperatures. The water uptake and germination rate of spinach seeds by 5 min treatment of RDBD was increased by 10% and 15%, respectively, and the standard error of germination was reduced by 4% in comparison with the controls. RDBD enables an important step forward in non-thermal atmospheric-pressure plasma agriculture for omnidirectional seed treatment. Full article
(This article belongs to the Special Issue Bio-Plasma for Molecular Science)
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Review

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27 pages, 10235 KiB  
Review
Persistence of Coronavirus on Surface Materials and Its Control Measures Using Nonthermal Plasma and Other Agents
by Sekar Ashokkumar, Nagendra Kumar Kaushik, Ihn Han, Han Sup Uhm, Jang Sick Park, Gyu Seong Cho, Young-Jei Oh, Yung Oh Shin and Eun Ha Choi
Int. J. Mol. Sci. 2023, 24(18), 14106; https://doi.org/10.3390/ijms241814106 - 14 Sep 2023
Cited by 7 | Viewed by 2182
Abstract
Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) has been responsible for the initiation of the global pandemic since 2020. The virus spreads through contaminated air particles, fomite, and surface-contaminated porous (i.e., paper, wood, and masks) and non-porous (i.e., plastic, stainless steel, and glass) materials. [...] Read more.
Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) has been responsible for the initiation of the global pandemic since 2020. The virus spreads through contaminated air particles, fomite, and surface-contaminated porous (i.e., paper, wood, and masks) and non-porous (i.e., plastic, stainless steel, and glass) materials. The persistence of viruses on materials depends on porosity, adsorption, evaporation, isoelectric point, and environmental conditions, such as temperature, pH, and relative humidity. Disinfection techniques are crucial for preventing viral contamination on animated and inanimate surfaces. Currently, there are few effective methodologies for preventing SARS-CoV-2 and other coronaviruses without any side effects. Before infection can occur, measures must be taken to prevent the persistence of the coronavirus on the surfaces of both porous and non-porous inanimate materials. This review focuses on coronavirus persistence in surface materials (inanimate) and control measures. Viruses are inactivated through chemical and physical methods; the chemical methods particularly include alcohol, chlorine, and peroxide, whereas temperature, pH, humidity, ultraviolet irradiation (UV), gamma radiation, X-rays, ozone, and non-thermal, plasma-generated reactive oxygen and nitrogen species (RONS) are physical methods. Full article
(This article belongs to the Special Issue Bio-Plasma for Molecular Science)
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