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Bio-Nano Interactions—3rd Edition

A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Nanoscience".

Deadline for manuscript submissions: 31 January 2025 | Viewed by 612

Special Issue Editor


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Guest Editor
Department of Comparative Biomedicine and Food Science, University of Padua, Viale dell’Università 16, 35020 Legnaro, Italy
Interests: protein corona; theranostic nanodevices; endogenous protein recognition; smart nanomaterial surfaces; iron oxide nanoparticles; selective protein binding; biosensing; drug delivery; stealth nanomaterials; biochemistry and biophysics
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Special Issue Information

Dear Colleagues,

I would like to invite you to submit a high-quality research paper for the Special Issue titled “Bio-Nano Interactions—3rd Edition” of the International Journal of Molecular Sciences. The story of materials from living (biotic) organisms is intensely intertwined with the one of inanimate (abiotic) materials, which might have played a crucial role in the chemical evolution in the prebiotic era and, therefore, in the origin of life. Nanoparticles and proteins are entities of the same size range and the understanding and the prediction of the interactions between proteins and nanoparticles represent the Holy Grail in nanoscience. Indeed, the crucial challenge is to endow nanoparticles of protein-like specificity with the ability to enable the abiotic material to specifically interact with all components of biological systems such as peptides, proteins, lipids, DNA, receptors, cells and whole organisms, including humans or animals.

Furthermore, the use of engineered biomolecules, such as nucleic acids, enabled us to develop self-assembled hybrid nano-objects with machine-like properties, using simple Watson–Crick base-pairing rules. On the other hand, the synthesis of inorganic nanomaterials with pseudo-enzymatic properties (nanozymes) allowed us to establish novel devices able to manipulate matter at the nanoscale level, leading nanoscientists a step forward with regard to mimicking nature.

The Special Issue “Bio-Nano Interactions—3rd Edition” encourages the publication of papers that expand the existing perspectives on the interplay of smart nanomaterials with biological interfaces as well as on the development of bio-inspired nanotechnologies.

Prof. Dr. Massimiliano Magro
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. International Journal of Molecular Sciences is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. There is an Article Processing Charge (APC) for publication in this open access journal. For details about the APC please see here. Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • nanoparticles
  • proteins
  • smart nanomaterial surfaces
  • selective protein binding
  • nanomaterials
  • abiotic material
  • biological systems
  • bio-inspired inorganic materials and DNA nanotechnologies

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Published Papers (1 paper)

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Research

16 pages, 7293 KiB  
Article
Highly Specific Polyphenolic Colloids as Alternatives to Antimicrobials in Livestock Production
by Andrea Laconi, Alessandro Cecconello, Simone Molinari, Graziano Rilievo, Aura Cencini, Federica Tonolo, Antonie Krystofova, Hardik Nilesh Majethia, Roberta Tolosi, Eliana Schiavon, Carlo Nicoletto, Alessandra Piccirillo, Fabio Vianello and Massimiliano Magro
Int. J. Mol. Sci. 2024, 25(17), 9363; https://doi.org/10.3390/ijms25179363 - 29 Aug 2024
Viewed by 506
Abstract
The dispersion of antibiotics in livestock farming represents a health concern worldwide, contributing to the spread of antimicrobial-resistant bacteria through animals, the environment, and humans. Phenolic compounds could be alternatives to antibiotics, once drawbacks such as their low water solubility, bioavailability, and reduced [...] Read more.
The dispersion of antibiotics in livestock farming represents a health concern worldwide, contributing to the spread of antimicrobial-resistant bacteria through animals, the environment, and humans. Phenolic compounds could be alternatives to antibiotics, once drawbacks such as their low water solubility, bioavailability, and reduced stability are overcome. Although nano- or micro-sized formulations could counter these shortcomings, they do not represent cost-effective options. In this study, three phenolic compounds, obtained from wood-processing manufacturers, were characterized, revealing suitable features such as their antioxidant activity, size, and chemical and colloidal stability for in-field applications. The minimum inhibitory concentration (MIC) of these colloidal suspensions was measured against six bacterial strains isolated from livestock. These particles showed different inhibition behaviors: Colloidal chestnut was effective against one of the most threatening antibiotic-resistant pathogens, i.e., S. aureus, but ineffective toward E. coli. Instead, colloidal pine showed a weak effect on S. aureus but specificity toward E. coli. The present proof-of-concept points at colloidal polyphenols as valuable alternatives for antimicrobial substitutes in the livestock context. Full article
(This article belongs to the Special Issue Bio-Nano Interactions—3rd Edition)
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