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Advanced Molecular Research on Chronic Heart Failure

A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Pathology, Diagnostics, and Therapeutics".

Deadline for manuscript submissions: 30 November 2024 | Viewed by 242

Special Issue Editor

Internal Medicine and Cardiovascular Ultrasound Unit, SS. Annunziata Hospital of Chieti, 66100 Chieti, Italy
Interests: heart failure; atrial fibrillation; cardiovascular medicine; cardiology; ultrasound; internal medicine; chronic heart failure; clinical practice
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

Chronic heart failure (CHF) is a complex clinical syndrome characterized by the heart's incapacity to effectively pump blood throughout the body to fulfill its metabolic requirements. It remains a significant challenge in cardiovascular medicine, affecting millions worldwide. Despite advances in treatment, the complex molecular mechanisms underlying CHF require further elucidation to develop targeted therapies and improve patient outcomes.

Moreover, various studies have suggested that almost 30–70% of HF patients have heart failure with preserved ejection fraction (HF-pEF), a complex clinical syndrome which is becoming a widespread challenge for daily clinical practice. In particular, amyloid infiltration of the myocardium, also called cardiac amyloidosis (CA), which has previously been considered a rare pathology, actually seems to be underestimated, resulting in approximately 15% of patients with HF-pEF.

This Special Issue aims to gather research on advanced molecular approaches to understanding and managing the disease. Submissions should address the intersection of molecular research with clinical practice, aiming to drive the field of cardiovascular medicine toward a more effective management of CHF. Topics of interest include, but are not limited to, the molecular pathways implicated in the pathogenesis of CHF disease, novel molecular imaging techniques for assessing cardiac function in CHF, biomarkers for early detection and prognosis of CHF, translational approaches of molecular research, clinical practice in CHF management and novel pharmacological treatment. Finally, extended consideration of CA should be made, a current emerging challenge in daily clinical practice and one of the most frequent causes of heart failure with preserved ejection fraction.

Dr. Marco Tana
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

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Keywords

  • chronic heart failure (CHF)
  • cardiovascular medicine
  • cardiac amyloidosis
  • biomarkers
  • translational ap-proaches
  • molecular approaches
  • pharmacological treatment
  • molecular mechanisms
  • molecular pathways
  • prognosis
  • clinical practice in CHF management

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Published Papers

This special issue is now open for submission.
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