Molecular Mechanisms of Bioactive Compounds Against Cancer—From Natural Sources to Drug Candidates
A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Bioactives and Nutraceuticals".
Deadline for manuscript submissions: 30 January 2025 | Viewed by 167
Special Issue Editor
Special Issue Information
Dear Colleagues,
Cancer remains a leading cause of death worldwide, prompting significant efforts to find effective drugs to reduce its mortality rate. The search for new anticancer compounds is focused heavily on natural sources, which offer rich chemical diversity. Bioactive secondary metabolites from various species of animals, plants, and microorganisms serve as excellent starting points for the synthesis of more potent analogues.
A significant challenge in cancer treatment is the development of resistance to chemotherapy, radiation therapy, and immunotherapy, which leads to tumor recurrence and metastasis. This resistance accounts for 90% of cancer-related deaths, making it a primary focus in oncology. Thus, the discovery of new active compounds continues to be a central objective in the development of innovative anticancer treatments.
The aim of this Special Issue is to compile original research papers and review articles that highlight recent progress made in the study of natural bioactive compounds and their derivatives in cancer treatment. This Special Issue encompasses the development, identification, and molecular mechanisms of action of potent anticancer drugs as well as undiscovered functions of already known bioactive compounds.
Dr. Agnieszka Pyrczak-Felczykowska
Guest Editor
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Keywords
- cancer
- bioactive compounds
- anticancer drugs
- cancer treatment
- natural products
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