Innovative Antimicrobial Therapies: Overcoming Virulence of Microorganisms and Drug Resistance
A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Microbiology".
Deadline for manuscript submissions: 30 October 2024 | Viewed by 111
Special Issue Editor
Interests: anaerobic bacteria; anti-infective agents; biofilm; pathobionts; virulence factors
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Microorganisms interact with the human body in a variety of ways: they can be commensals, mutualists, or absolute pathogens. Infectious disease is the result of the virulence of the microorganism, the condition of the host, and the presence of various favourable environmental factors. Understanding complex host–microbe and microbe–microbe interactions can help us to identify the specific role of microorganisms in human health and disease and allows for targeted interventions. Antibiotics, antivirals, antifungals, and antiparasitic drugs are now widely used to prevent and treat human infections. The price of widespread access to anti-infectives is the development of antimicrobial resistance (AMR). AMR is one of the top 10 threats to global health. Resistant and multi-drug resistant pathogens are a major public health problem, leading to increased mortality and morbidity.
New treatment strategies and a new generation of therapies are urgently needed. Drugs with unique chemical structures, new mechanisms of action and high barriers to resistance can be an answer to the multi-faceted global challenge of AMR, also known as the “silent pandemic”.
Dr. Anna Majewska
Guest Editor
Manuscript Submission Information
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Keywords
- antibiotics
- antimicrobial resistance
- antivirals
- commensal
- pathogenesis
- virulence
