ijms-logo

Journal Browser

Journal Browser

Molecular Cages: Design, Synthesis, and Applications

A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Macromolecules".

Deadline for manuscript submissions: 31 December 2024 | Viewed by 965

Special Issue Editor


E-Mail Website
Guest Editor
Instituto Interuniversitario de Investigación de Reconocimiento Molecular y Desarrollo Tecnológico (IDM), Universitat Politècnica de València, Universitat de València, Camino de Vera s/n, 46022 Valencia, Spain
Interests: supramolecular chemistry
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

Molecular cage structures, including metal–organic cages and purely organic cages, represent a hallmark in the supramolecular chemistry field due to their unique properties, typically compared with enzymes. The design of their structures at the molecular level allows for creating functional structures with specific applications, including catalysis, molecular recognition, stabilization of chemical species and separation processes. Additionally, they can have biological applications, among many others. An important aspect in the field is represented by the structural requirements of the cages should possess for the target applications. To achieve this, a combination of modeling and synthetic protocols is necessary. Many researchers have contributed with excellent expertise mainly in synthetic chemistry, making the expansion of this research field possible.

Thus, this Special Issue will discuss the recent advances in these aspects. Contributions with topics related to this research, in either design, synthesis or applications of molecular cages, including both research and review articles, are welcome.

Dr. Vicente Martí-Centelles
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. International Journal of Molecular Sciences is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. There is an Article Processing Charge (APC) for publication in this open access journal. For details about the APC please see here. Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • molecular cages
  • supramolecular chemistry
  • synthetic chemistry
  • self-assembly
  • molecular design
  • host–guest chemistry
  • biological applications

Benefits of Publishing in a Special Issue

  • Ease of navigation: Grouping papers by topic helps scholars navigate broad scope journals more efficiently.
  • Greater discoverability: Special Issues support the reach and impact of scientific research. Articles in Special Issues are more discoverable and cited more frequently.
  • Expansion of research network: Special Issues facilitate connections among authors, fostering scientific collaborations.
  • External promotion: Articles in Special Issues are often promoted through the journal's social media, increasing their visibility.
  • e-Book format: Special Issues with more than 10 articles can be published as dedicated e-books, ensuring wide and rapid dissemination.

Further information on MDPI's Special Issue polices can be found here.

Published Papers (1 paper)

Order results
Result details
Select all
Export citation of selected articles as:

Research

13 pages, 2333 KiB  
Article
Synthesis of a Pd2L4 Hydrazone Molecular Cage Through Multiple Reaction Pathways
by Giovanni Montà-González, Ramón Martínez-Máñez and Vicente Martí-Centelles
Int. J. Mol. Sci. 2024, 25(22), 11861; https://doi.org/10.3390/ijms252211861 - 5 Nov 2024
Viewed by 694
Abstract
Molecular cages are preorganized molecules with a central cavity, typically formed through the reaction of their building blocks through chemical bonds. This requires, in most cases, forming and breaking reversible bonds during the cage formation reaction pathway for error correction to drive the [...] Read more.
Molecular cages are preorganized molecules with a central cavity, typically formed through the reaction of their building blocks through chemical bonds. This requires, in most cases, forming and breaking reversible bonds during the cage formation reaction pathway for error correction to drive the reaction to the cage product. In this work, we focus on both Pd–ligand and hydrazone bonds implemented in the structure of a Pd2L4 hydrazone molecular cage. As the cage contains two different types of reversible bonds, we envisaged a cage formation comparative study by performing the synthesis of the cage through three different reaction pathways involving the formation of Pd–ligand bonds, hydrazone bonds, or a combination of both. The three reaction pathways produce the cage with yields ranging from 73% to 79%. Despite the complexity of the reaction, the cage is formed in a high yield, even for the reaction pathway that involves the formation of 16 bonds. This research paves the way for more sophisticated cage designs through complex reaction pathways. Full article
(This article belongs to the Special Issue Molecular Cages: Design, Synthesis, and Applications)
Show Figures

Graphical abstract

Back to TopTop