Metabolomic Approaches to Bioactive Molecules Discovery
A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Informatics".
Deadline for manuscript submissions: closed (30 September 2023) | Viewed by 1908
Special Issue Editor
Interests: metabolomic; chemical characterization of natural products; determination of pollutants in environmental matrices; food chemistry
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Metabolomics is a systematic approach for an in-depth analysis of complex mixtures in order to identify their secondary metabolites. These metabolites, characterized by a high chemical complexity, can perform crucial functions for the understanding of metabolic processes. The levels of metabolites can alter following exposure to external stress conditions. Therefore, the application of highly sensitive analytical techniques for the detection of these metabolites becomes essential. The use of untargeted metabolomics methods based on ultra-high performance liquid chromatography-mass spectrometry (UPLC-MS), gas chromatography-mass spectrometry (GC-MS) and also nuclear magnetic resonance (NMR) are ideal for exploring metabolic pathways and detecting biomarkers. Environmental metabolomics have immense potential and represent the routine tool for elucidating the relationships between metabolite levels expressed by organisms and environmental stress and for describe metabolic profiling and fingerprinting.
Dr. Stefania Garzoli
Guest Editor
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Keywords
- metabolites
- metabolomic profile
- chromatographic and spectrometric techniques
- NMR
- bioactive compounds
- markers
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