New Trends in Research on Cerebral Ischemia
A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Neurobiology".
Deadline for manuscript submissions: 31 August 2024 | Viewed by 1036
Special Issue Editor
Special Issue Information
Dear Colleagues,
This Special Issue delves into the intricate relationship between white matter damage resulting from ischemia and the potential for axon regeneration via the application of innovative interventions such as cell transplantation and exosome therapy. Ischemia-induced white matter injury is a major contributor to neurological disorders, leading to significant cognitive and motor impairments.
Through a comprehensive analysis of current research, this Special Issue aims to thoroughly examine the underlying mechanisms of white matter damage in ischemia, with a particular emphasis on its detrimental effects on axonal structures and myelin integrity. The molecular and cellular alterations triggered by ischemic events are elucidated, shedding light on the factors influencing the regenerative potential of axons.
The primary focus of this Special Issue is the exploration of cutting-edge interventions that exhibit promise in promoting axon regeneration. Cell transplantation emerges as a leading strategy, harnessing the regenerative capacity of stem cells to replace damaged cells and facilitate neural repair. Additionally, this Special Issue aims to delve into the emerging field of exosome therapy, which utilizes extracellular vesicles in order to deliver the therapeutic cargo, stimulate growth, and modulate the regenerative response within the affected white matter.
By synthesizing insights from various studies and clinical trials, this Special Issue will not only advance our understanding of ischemia-induced white matter damage, but also offer a glimpse into the potential of groundbreaking interventions for axon regeneration. This research will pave the way for enhanced treatments and functional recovery in patients affected by white matter injuries.
Dr. Hideaki Imai
Guest Editor
Manuscript Submission Information
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Keywords
- white matter damage
- ischemia
- axon regeneration
- intervention
- cell transplantation
- exosome therapy
- stem cells
- myelin integrity
- neurological disorders
- neural repair
- cognitive impairments
