Extracellular Vesicles in Reproduction—3rd Edition
A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Endocrinology and Metabolism".
Deadline for manuscript submissions: closed (31 August 2024) | Viewed by 4033
Special Issue Editors
Interests: andrology; reproductive biotechnologies; gamete interactions
Special Issues, Collections and Topics in MDPI journals
Interests: spermatozoa; seminal plasma; extracellular vesicles; proteomics; cytokines
Special Issues, Collections and Topics in MDPI journals
Interests: animal reproduction
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
The homeostasis of an individual depends on the ability of the differences cells, systems, and body compartments to interact via complex processes of communication. Among these, we know of humoral, hormonal, and nervous processes, and from the initial findings from the 1960s to today, we also understand the role of cell-derived vesicles in communicating cell-to-cell beyond intercellular organized contacts, as well as knowing of vesicles that circulate in intercellular matrixes and secretions, lymph fluid, or blood to gain contact and mediate stimulus and responses at long distances from the originating cell. These extracellular vesicles (EVs) are further distinguished as exosomes, microvesicles, or apoptotic bodies, the latter being mostly related to cell death and nearby, local contacts, while the former types are related to systemic cell communication. All EVs have in common that they carry loads of molecules (proteins, peptides, lipids, carbohydrates, and nucleic acids) or even organelles (apoptotic bodies) with the capacity to respond to stimuli, intervene in metabolic pathways, or influence gene expression. Often having the characteristics of the originating cell, they serve as biomarkers of origin and of function beyond a specific target. The reproductive system is able to communicate via EVs, with some EVs playing important roles in spermatogenesis, sperm maturation, oogenesis, and embryogenesis, as well as influencing other systems, including the immune system, to modulate immune responses during the development and function of hemi-allogeneic organs for the survival of the fetus throughout pregnancy.
This Special Issue of IJMS is focused on “Extracellular Vesicles in Reproduction”. The issue welcomes papers covering EVs’ characterization, quantification, disclosure of their load, and elucidation of their biogenesis and roles when modulating reproductive events. This Special Issue welcomes novel research, specifically that which deals with comparative aspects but also that in the form of methodological papers, in addition to insightful and critical reviews in these areas.
Prof. Dr. Heriberto Rodriguez-Martinez
Prof. Dr. Jordi Roca
Prof. Dr. Emilio A. Martinez
Guest Editors
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Keywords
- extracellular vesicles
- exosomes
- microvesicles
- apoptotic bodies
- reproductive processes
- spermatogenesis
- sperm maturation
- seminal plasma
- spermatozoa
- sperm capacitation
- fertility
- pregnancy
- immune modulation
- immune tolerance
- proteomics
- transcriptomics
- epigenomics
- metabolomics
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