Chemokine Receptor and Ligands on Pain and Itch
A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Immunology".
Deadline for manuscript submissions: closed (30 June 2022) | Viewed by 4299
Special Issue Editors
Interests: role of cannabinoids and the endocannabinoid system in pain and itch; modulation of neuroinflammation by cannabinoids and opioids for pain, itch, and reward
Interests: role of chemokine and cytokine release during development of acute and chronic pain and itch; heterologous desensitization between chemokines and opioids; therapeutic value of chemokine receptor antagonists alone and in combination with opioids for pain and itch; pruritic and antipruritic effects of kappa opioid receptor ligands
Special Issue Information
Dear Colleagues,
Studies on chemokine receptors and their ligands evidently showed that they play an important role in the development of chronic pain and itch. Latest reports clearly indicate that prevalence of patients suffer from chronic itch is as high as in chronic pain. Despite increased research on development of effective analgesic and antipruritic compounds without severe side effects, still there is no effective medication approved for both condition other than opioids. A Special Issue of the International Journal of Molecular Sciences on “Chemokine receptors and ligands on pain and itch: Potential therapeutic applications of chemokine receptor antagonists” aims to bring attention on chemokine receptors and their ligands as novel molecular targets for pain and itch, and to new compounds in clinical development for treating chronic pain and itch.
Research articles and reviews on basic, preclinical, and clinical studies with biomolecular results are all welcome.
Dr. Sara Jane Ward
Dr. Saadet Inan
Guest Editors
Manuscript Submission Information
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Keywords
- chemokine receptor
- chemokines
- cytokines
- chemokine receptor antagonist
- acute pain
- chronic pain
- acute itch
- chronic itch
- scratching
- allodynia
- neuropathic pain
- neuropathic itch
- neuroinflammation
