Inflammation in the CNS and PNS: From Molecular Basis to Therapy
A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Immunology".
Deadline for manuscript submissions: closed (31 October 2022) | Viewed by 28095
Special Issue Editors
Interests: molecular mechanisms of neurodegeneration; amyotrophic lateral sclerosis; neuroinflammation; microglia; fibrosis; astrocytes; animal models of neurodegenerative diseases; purinergic signaling; histaminergic signaling; neuropharmacology
Special Issues, Collections and Topics in MDPI journals
Interests: microglia; astrocytes; neuroinflammation; amyotrophic lateral sclerosis (ALS); neurodegenerative diseases; non-cell autonomous neurodegeneration; mutant SOD1; FUS; fibro-glial scar; extracellular matrix; Friedreich's ataxia; RNA splicing
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Many advances have been made in the understanding of the nervous system pathophysiology; however, several instances have yet to be completely clarified. In particular, the effects of acute and chronic inflammation require further investigation. Neuroinflammation often precedes and worsens neuron death, and its inhibition has proved to be one of the most efficient methods of slowing down neurological disease progression. Nevertheless, it is recognized that inflammatory responses could have beneficial functions, assisting in repair and recovery processes.
This Special Issue aims to cover all areas of molecular-based and preclinical research to study the role played in human diseases by inflammation of the central and peripheral nervous system. Original research, reviews, and short communication articles are welcome, and clinical submissions with biomolecular experiments are especially encouraged.
Cellular and molecular analyses, as well as potential therapeutic targets concerning conditions such as Alzheimer’s disease, amyotrophic lateral sclerosis, ataxias, Huntington’s disease, multiple sclerosis, Parkinson’s disease, peripheral neuropathies, stroke, and spinal cord and brain injuries, will be explored.
Dr. Savina Apolloni
Prof. Dr. Nadia D'Ambrosi
Guest Editors
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Keywords
- microglia
- redox homeostasis
- central nervous system
- peripheral nervous system
- neuroinflammation
- nervous system pathophysiology
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