Role of Neuronal Guidance Cues in Inflammation
A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Neurobiology".
Deadline for manuscript submissions: closed (31 October 2021) | Viewed by 3701
Special Issue Editor
Interests: axonal guidance cues; endothelium; monocyte; macrophage; atherosclerosis; netrin; cell biology
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Acute and chronic inflammation are crucial mechanisms underlying multiple physiological and pathological processes. It has become increasingly clear that neuronal guidance cues, such as netrin and semaphorin—proteins known for directing cell and axon migration during neural development—also play a central role in (pathological) immune responses, both in the onset as the resolution of inflammation. Of interest are the bidirectional communication between the immune system and the nervous system important in regulating immunological mechanisms. Extending our knowledge of the immune regulatory functions of neuronal guidance cues can contribute to future therapeutic strategies for various inflammatory diseases, such as neurodegenerative diseases, rheumatoid arthritis, asthma, systemic lupus erythematosus, and atherosclerosis.
The scope of this Special Issue covers the various roles of neuronal guidance cues in inflammation. We welcome authors to contribute original research articles as well as review articles with the aim to further unravel the role of neuronal guidance molecules in inflammation. We encourage the submission of papers approaching the topic from different points of view and different levels, from the immune system or the nervous system, and from basic molecular mechanisms to translational approaches.
Dr. Janine van Gils
Guest Editor
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Keywords
- axonal guidance cues
- inflammation
- netrin
- semaphorin
- cell biology
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