Plant-Derived Biologics and Other High-Value Compounds
A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Plant Sciences".
Deadline for manuscript submissions: closed (30 November 2022) | Viewed by 24266
Special Issue Editors
Interests: systems biology; bioinformatics; plant and medical biotechnology; bionanotechnology, molecular farming
2. Department of Plant Physiology and Molecular Biology, University of Plovdiv, 4000 Plovdiv, Bulgaria
Interests: molecular farming; recombinant proteins; plant biotechnology; vaccines; virology; zoonotic viruses
Special Issue Information
Dear Colleagues,
Over the last twenty years, remarkable progress has been made in the field of plant-produced biologics. Soon we may even witness the first licensed plant-derived vaccines against influenza and SARS-CoV-2. Plant expression systems have a unique place among expression platforms more broadly. They allow plants to produce high-value recombinant biological compounds with high productivity and scalability, at а lower cost. Shortened R&D time, improved plant expression vectors, enhanced downstream processing, modified plant-glycosylation patterns to better match those observed in animals and humans – these aspects and more have helped advance the development of plant molecular farming (PMF) significantly.
This Special Issue of “Molecular Science” aims to highlight recent developments in and applications of plant expression systems and plant-derived biologics, as well as to evaluate their technical feasibility and economic implications.
Prof. Dr. Ivan Minkov
Dr. Gergana Zahmanova
Guest Editors
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Keywords
- plant molecular farming (PMF)
- biologics
- vaccine candidates
- monoclonal antibodies (mAbs)
- diagnostic tools
- virus-like particles (VLPs)
- plant expression vectors
- glycoengineering
- posttranslational modification
- economic impact evaluation
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