Antioxidant and Cellular Defense Properties of Phytochemicals
A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Plant Sciences".
Deadline for manuscript submissions: closed (28 February 2022) | Viewed by 13172
Special Issue Editor
Interests: phytochemicals; chemoprevention; antioxidant defences; anti-inflammation; hair growth; phase II enzymes; signal transduction
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Phytochemicals, bioactive chemical compounds found in plants, have long been studied for their potential health benefits. Of the diverse health benefits of phytochemicals, the ability to protect cells and tissues could be considered as the first line of defense. Many phytochemicals have been shown to induce cellular defense mechanisms against exposure to various endogenous and exogenous toxicants as well as reactive oxygen and nitrogen species (ROS/RNS). Phytochemicals possess the ability to directly neutralize ROS/RNS or to indirectly enhance the antioxidant and phase II detoxifying enzymes. These phytochemicals may regulate transcription factors or upstream signaling kinases involved in antioxidant and detoxifying defense systems. Inhibition of pro-inflammatory and carcinogenic molecular targets is also a cellular defense strategy of phytochemicals to prevent chronic diseases and maintain health. Improving gut microbiome profile by phytochemicals could be another recent approach to enhance the defense ability.
This Special Issue calls for original research articles and full/mini reviews that address the progress and current understanding in the overlapping research topics of “Antioxidant and Cellular Defense Properties of Phytochemicals”.Prof. Dr. Woo-Sik Jeong
Guest Editor
Manuscript Submission Information
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Keywords
- phytochemicals
- cellular defense mechanisms
- antioxidant enzymes
- phase II detoxifying enzymes
- anti-inflammation
- signal transduction pathway
- chemoprevention
- microbiome
