ijms-logo

Journal Browser

Journal Browser

Stem Cell and Exosome Therapy for Tissue Regeneration

A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Biology".

Deadline for manuscript submissions: closed (31 August 2023) | Viewed by 2981

Special Issue Editor


E-Mail Website
Guest Editor
Wake Forest Institute for Regenerative Medicine, Wake Forest School of Medicine, Winston‐Salem, NC 27101, USA
Interests: stem cells; tissue engineering; biomaterials; 3D organoids; regenerative medicine

Special Issue Information

Dear Colleagues,

The aim of this Special Issue is to collect original research, and review articles, focusing on the novel technologies on stem cell, exosome and molecular targeted therapy for long-term tissue repair, and 3D tissue engineering for disease modeling and drug testing. This proposal will encourage discussion among investigators about the thoughts on initiating the promising therapeutic strategies to promote tissue regeneration and the application of bioengineered technology.

Potential topics:

  • Strategies to optimize stem cell therapy to long-term tissue regeneration;
  • Cell or exosome therapy for anti-aging therapy;
  • Molecular targeted therapy to promote anti-scarring, wound healing and chronic tissue repair;
  • 3D cultures for the assessment of drugs, or chemics-induced toxicities, particularly nephrotoxicity, hepatotoxicity or mitotoxicity.

Dr. Yuanyuan Zhang
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. International Journal of Molecular Sciences is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. There is an Article Processing Charge (APC) for publication in this open access journal. For details about the APC please see here. Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • tissue engineering
  • tissue repair
  • stem cells therapy
  • exosome therapy
  • molecular targeted therapy
  • antiaging therapy
  • 3D cultures, organoids or spheroid
  • disease modeling

Benefits of Publishing in a Special Issue

  • Ease of navigation: Grouping papers by topic helps scholars navigate broad scope journals more efficiently.
  • Greater discoverability: Special Issues support the reach and impact of scientific research. Articles in Special Issues are more discoverable and cited more frequently.
  • Expansion of research network: Special Issues facilitate connections among authors, fostering scientific collaborations.
  • External promotion: Articles in Special Issues are often promoted through the journal's social media, increasing their visibility.
  • e-Book format: Special Issues with more than 10 articles can be published as dedicated e-books, ensuring wide and rapid dissemination.

Further information on MDPI's Special Issue polices can be found here.

Published Papers (1 paper)

Order results
Result details
Select all
Export citation of selected articles as:

Review

14 pages, 1469 KiB  
Review
Therapeutic Benefits of Stem Cells and Exosomes for Sulfur-Mustard-Induced Tissue Damage
by Carol Christine Bosholm, Hainan Zhu, Pengfei Yu, Kun Cheng, Sean Vincent Murphy, Patrick Michael McNutt and Yuanyuan Zhang
Int. J. Mol. Sci. 2023, 24(12), 9947; https://doi.org/10.3390/ijms24129947 - 9 Jun 2023
Cited by 3 | Viewed by 2520
Abstract
Sulfur mustard (SM) is a highly toxic chemical agent that causes severe tissue damage, particularly to the eyes, lungs, and skin. Despite advances in treatment, there is a need for more effective therapies for SM-induced tissue injury. Stem cell and exosome therapies are [...] Read more.
Sulfur mustard (SM) is a highly toxic chemical agent that causes severe tissue damage, particularly to the eyes, lungs, and skin. Despite advances in treatment, there is a need for more effective therapies for SM-induced tissue injury. Stem cell and exosome therapies are emerging as promising approaches for tissue repair and regeneration. Stem cells can differentiate into multiple cell types and promote tissue regeneration, while exosomes are small vesicles that can deliver therapeutic cargo to target cells. Several preclinical studies demonstrated the potential of stem cell, exosome, or combination therapy for various tissue injury, showing improvements in tissue repairing, inflammation, and fibrosis. However, there are also challenges associated with these therapies, such as the requirement for standardized methods for exosome isolation and characterization, the long-term safety and efficacy and reduced SM-induced tissue injury of these therapies. Stem cell or exosome therapy was used for SM-induced eye and lung injury. Despite the limited data on the use for SM-induced skin injury, this therapy is a promising area of research and may offer new treatment options in the future. In this review, we focused on optimizing these therapies, evaluating their safety and efficacy, and comparing their efficacy to other emerging therapeutic approaches potentially for SM-induced tissue injury in the eye, lung, and skin. Full article
(This article belongs to the Special Issue Stem Cell and Exosome Therapy for Tissue Regeneration)
Show Figures

Figure 1

Back to TopTop