Metal-Organic Frameworks (MOFs)-Based Nanomaterials as Highly Efficient Drug/Gene Agents
A special issue of Inorganics (ISSN 2304-6740). This special issue belongs to the section "Bioinorganic Chemistry".
Deadline for manuscript submissions: closed (31 October 2022) | Viewed by 1438
Special Issue Editors
2. Department of Physics, Sharif University of Technology, Tehran P.O. Box 11155-9161, Iran
Interests: bioinorganic chemistry; gene delivery; metallocenter assembly; drug delivery; structure/function relationships in metal coordination chemistry; biomedical engineering; biomaterials; inorganic chemisry; metal-organic frameworks (MOFs); CRISPR/Cas9; CRISPR technology; porous nanomaterials; nanotechnology; biotechnology
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Interests: green chemistry; biomass valorization; heterogeneous catalysis; nanomaterial design
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Special Issue Information
Dear Colleagues,
Several attempts have been made in the design, synthesis, characterization and optimization of different types of nanomaterials and non-viral drug/gene delivery vectors. In this regard, porous nanomaterials including metal–organic frameworks (MOFs), covalent–organic frameworks (COFs), zeolites and organic porous nanomaterials have been studied. Some critical factors for biomedical optimization include zeta potential, hydrodynamic particle size, molecular weight, cytotoxicity, cytocompatibility, bioavailability and other physicochemical/biological properties. MOF-based nanomaterials show superior behaviour compared to other types of porous nanomaterials; therefore, the importance and popularity of research is increasing all the time. MOFs are useful due to their high potential in optimizing physicochemical performance as well as biological performance. Additionally, their cytotoxicity on different cells lines depends on different mechanisms; therefore, investigating their potential as promising nanocarriers for efficient drug/gene delivery applications is of great importance.
In this Special Issue, we wish to cover the most recent advances in all these aspects of MOF-based nanomaterials biochemistry for targeted and efficient drug/gene delivery applications, by hosting a mix of original research articles and short critical reviews.
Dr. Navid Rabiee
Prof. Dr. Rafael Luque
Guest Editors
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Keywords
- MOFs biochemistry
- drug/gene delivery
- targeted delivery
- CRISPR/Cas9
- CRISPR technology
- gene editing
- chemotherapy
- photothermal therapy
- cancer therapy
- non-viral drug/gene delivery vectors
- green synthesis
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