Enteric Nervous System: Neuropathic Gastrointestinal Motility—2nd Edition

Special Issue Editors


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Guest Editor
Department of Clinical and Experimental Medicine, University of Pisa, 56126 Pisa, Italy
Interests: inflammatory bowel diseases; inflammation; intestinal functional disorders; animal models; gut–brain axis; obesity; patients
Special Issues, Collections and Topics in MDPI journals

E-Mail Website
Guest Editor
Department of Clinical and Experimental Medicine, University of Pisa, 56126 Pisa, Italy
Interests: inflammatory bowel disease; phytochemicals; prebiotics; probiotics; small molecules; gut–brain axis; enteric glial network; pharmacological approaches; obesity; intestinal organoids
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

We are thrilled to announce the release of the second volume of our Special Issue, entitled "Enteric Nervous System: Neuropathic Gastrointestinal Motility—2nd Edition". Patients with both digestive and extra-digestive diseases, including inflammatory bowel diseases (IBDs), irritable bowel syndrome (IBS), intestinal infections, metabolic syndromes, and neurological disorders, are often characterized by severe gastrointestinal (GI) dysfunctions, such as dysphagia, infrequent bowel movements, and constipation. In this context, several pieces of evidence suggest that gut dysbiosis, impairments of enteric epithelial barrier, and intestinal immune/inflammatory responses promote neuroplastic changes in the enteric nervous system, which could contribute to bowel motor dysfunctions.

On this basis, the purpose of this Special Issue is to characterize the involvement of the enteric bacteria–neuro–immune system in the pathophysiology of GI dysmotility associated with digestive and extra-digestive diseases. The understanding of these aspects could be useful for the identification of common pathophysiologic features underling GI dysfunctions in a plethora of diseases and for providing further insights for the development of new therapeutic strategies.

We invite you to visit the following link to access the first volume of our Special Issue.

https://www.mdpi.com/journal/jcm/special_issues/enteric_nervous.

We encourage submissions of both original research articles and reviews.

Dr. Carolina Pellegrini
Dr. Vanessa D'Antongiovanni
Guest Editors

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Keywords

  • gastrointestinal dysmotility
  • intestinal inflammation
  • enteric bacteria–neuro–immune network
  • brain–gut axis
  • metabolic disorders
  • neurological disorders
  • enteric neuroplasticity

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