New Perspectives in Liver Transplantation and Biliary Complications

Dear Colleagues,

We are pleased to invite you to contribute your valuable articles to our medical journal, focusing on the theme “New Perspectives in Liver Transplantation and Biliary Complications”. This highly relevant medical topic requires in-depth scientific and clinical exploration, and your contribution could make a significant difference in improving medical practices and patient outcomes.

Liver transplantation represents one of the most complex and delicate surgical procedures, and biliary complications are among the most common and challenging issues that can arise post-operatively. The organ shortage imposes the use of increasingly marginal donors, both among dead brain donors (DBD) and among dead cardiocirculatory donors (DCD). The acceptance of expanded criteria grafts results in increased rates of cholangiopathy driven by ischemia/reperfusion injury (IRI). The adoption of innovative protocols before and after liver transplant has demonstrated encouraging results in reducing cholangiopathy rates. Machine perfusions allow better preservation of liver grafts or a more accurate ex vivo assessment of the expression of IRI. Furthermore, medications on the graft, both in the pre- and post-implantation phases, can further reduce the injury expressed by the liver graft.

Articles exploring new surgical techniques, pre- and post-operative management protocols, and innovative studies are particularly welcomed.

We invite you to share your clinical experiences, original research, and literature reviews that can contribute to a better understanding of the biliary complications in the context of liver transplantation. Each article will undergo rigorous peer review to ensure the highest scientific quality.

We are confident that your expertise and dedication will provide valuable insights to the medical community and improve the management of patients undergoing liver transplantation.

We are available to provide any further information and clarification.

Dr. Marco Maria Pascale
Dr. Francesco Frongillo
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Journal of Clinical Medicine is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

• liver transplant
• cholangiopathy
• ischemia/reperfusion injury
• machine perfusion
• extended-criteria donors