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New Insights into Head and Neck Surgery
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New Insights into Head and Neck Surgery

A special issue of Journal of Clinical Medicine (ISSN 2077-0383). This special issue belongs to the section "General Surgery".

Deadline for manuscript submissions: 30 November 2024 | Viewed by 1498

Special Issue Editor

Dr. Gábor Répássy

E-Mail Website
Guest Editor
Department of Otorhinolaryngology, Head and Neck Surgery, Semmelweis University, 1083 Budapest, Hungary
Interests: otorhinolaryngology; head and neck surgery; laryngeal surgery; thyroid gland surgery; salivary gland surgery; endoscopic sinus surgery

Special Issue Information

Dear Colleagues,

Over the past few years, head and neck surgery has evolved and undergone a great development. New surgical procedures and technological innovations have been presented in the fields of ear surgery, sinonasal surgery, skull base surgery, head and neck tumor surgery, salivary gland surgery and thyroid gland surgery. Alongside these, reconstructive surgical procedures have evolved, improving patients' functional and aesthetic outcomes. Moreover, the head and neck surgery field has experienced a strong and broad collaboration with other specialties, such as with orbital and maxillofacial/dentoalveolar surgeons or neurosurgeons, which aims for a better outcome. The objectives of these innovations and collaborations are to treat lesions that previously were seemingly impossible, to reduce surgical complications and to advance the prognosis of head and neck tumor patients.

The aim of this Special Issue is to explore and describe the latest surgical and/or technological innovations and collaborations in these surgical areas. I ask you to send in your latest research and findings on this topic and am looking forward to receiving your manuscripts.

Dr. Gábor Dénes Répássy
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Journal of Clinical Medicine is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • otorhinolaryngology
  • head and neck surgery
  • ear surgery
  • sinonasal surgery
  • skull base surgery
  • salivary gland surgery
  • thyroid gland surgery
  • head and neck cancer surgery

Published Papers (4 papers)

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Research

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13 pages, 812 KiB  
Article
Influencing Factors of Survival in Hypopharyngeal Squamous Cell Cancer
by Gábor Dénes Répássy, Dóra Hargas, András Molnár, Stefani Maihoub and László Tamás
J. Clin. Med. 2024, 13(13), 3853; https://doi.org/10.3390/jcm13133853 - 30 Jun 2024
Viewed by 163
Abstract
Objectives: This study examined the effects of various factors on survival in hypopharyngeal cancer, involving a total of 100 patients. Methods: Comorbidities, treatment modalities, survival times, and potential factors affecting survival were retrospectively analysed. The expression of p16 was also examined. A statistical [...] Read more.
Objectives: This study examined the effects of various factors on survival in hypopharyngeal cancer, involving a total of 100 patients. Methods: Comorbidities, treatment modalities, survival times, and potential factors affecting survival were retrospectively analysed. The expression of p16 was also examined. A statistical analysis was conducted using IBM SPSS V25 software. Results: The mean overall survival time was determined to be 30.8 months. Smoking was observed in 95%, and regular alcohol consumption was reported in 75% of the cases. The expression of p16 did not significantly affect survival (p = 0.74) or the maximum tumour size (p = 0.21). The Kaplan–Meier method demonstrated significantly longer survival times (p = 0.047 *) in the group that underwent partial pharyngolaryngectomy with or without adjuvant therapy (median: 75.25 months, 95% CI: 31.57–118.93), compared to the other four treatment groups (i.e., total laryngectomy with pharyngectomy with or without adjuvant therapy, chemoradiation, chemotherapy, and radiotherapy). Conclusions: The study found that factors such as sex, comorbidities (e.g., type 2 diabetes and chronic obstructive pulmonary disease), TNM and stage, weight loss, smoking, and alcohol consumption did not have a significant effect on survival. In conclusion, the longest survival was observed after partial pharyngolaryngectomy with or without adjuvant therapy. Risk factors and comorbidities did not show a significant effect on survival. p16 expression was not a factor that affected either survival or tumour size. Full article
(This article belongs to the Special Issue New Insights into Head and Neck Surgery)
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10 pages, 1078 KiB  
Article
Is Oral Microflora Related to Development of Malfunction in Patients Using Voice Prosthesis?
by Angelo Immordino, Francesco Dispenza, Federico Sireci, Riccardo Anzalone, Palmira Immordino, Cinzia Calà, Salvatore Gallina and Francesco Lorusso
J. Clin. Med. 2024, 13(12), 3492; https://doi.org/10.3390/jcm13123492 - 14 Jun 2024
Viewed by 321
Abstract
Background: this prospective study investigated the correlation between the oral bacterial microflora and the microflora found in voice prostheses (VPs) among 20 patients who had undergone laryngectomy. The aim was to explore the associations between the microflora’s presence and the malfunction of [...] Read more.
Background: this prospective study investigated the correlation between the oral bacterial microflora and the microflora found in voice prostheses (VPs) among 20 patients who had undergone laryngectomy. The aim was to explore the associations between the microflora’s presence and the malfunction of VPs, along with the association between the predominant microorganism and the longevity of VPs. Methods: the research process included gathering medical histories, conducting ENT examinations, replacing VPs, and performing check-ups every four months for a period of 15.5 months. Additionally, microbiological examinations, blood tests, and voice change surveys were conducted. Results: a correlation between the microflora isolated from VPs and that from oral rinses was demonstrated in a large percentage of patients who experienced a loss of prosthetic functional efficiency. The correlation analysis between the type of microorganism and the lifespan of VPs showed a non-significant Pearson correlation coefficient (r = 0.043, p = 0.678). Conclusions: there is no significant linear correlation between the predominant microorganism and the average lifespan of VPs. Full article
(This article belongs to the Special Issue New Insights into Head and Neck Surgery)
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12 pages, 264 KiB  
Article
Platelet-Rich Fibrin Treatment Evaluation in Patients with Medication-Related Osteonecrosis of the Jaw and Osteoradionecrosis
by Rareș Călin Roman, Mădălina Anca Moldovan, Loredana Sabrina Pop, Sergiu Megieșan and Cosmin Ioan Faur
J. Clin. Med. 2024, 13(12), 3473; https://doi.org/10.3390/jcm13123473 - 14 Jun 2024
Viewed by 355
Abstract
Background. Medication-related osteonecrosis of the jaw (MRONJ) and osteoradionecrosis (ORN) are associated with severe disability and continuous pain, both of which are very difficult to control. This study aims to evaluate the outcome of platelet-rich fibrin (PRF) treatment compared to iodoform gauze packing [...] Read more.
Background. Medication-related osteonecrosis of the jaw (MRONJ) and osteoradionecrosis (ORN) are associated with severe disability and continuous pain, both of which are very difficult to control. This study aims to evaluate the outcome of platelet-rich fibrin (PRF) treatment compared to iodoform gauze packing and the primary suture of oral mucosa in patients with both MRONJ and ORN. Methods. Patients suffering from MRONJ and ORN who were treated in the Oral and Maxillofacial Surgery Clinic of Cluj-Napoca in the last 10 years were selected for this study from the hospital database. Results. PRF treatment proved to be a reliable method to help heal the necrotic bone sites. High-ASA risk patients and immunosuppressed patients are more prone to recurrence and persistent signs and symptoms. Intravenous bisphosphonates produce more intense symptomatology compared to oral administration. The posterior mandible is more difficult to treat compared to other sites. Conclusions. The quality of life of MRONJ and ORN patients may be improved by a protocol that reduces pain and hospitalization. Full article
(This article belongs to the Special Issue New Insights into Head and Neck Surgery)

Review

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19 pages, 10519 KiB  
Review
New Insights into Cervicofacial Vascular Anomalies
by Daniela Vrinceanu, Mihai Dumitru, Andreea Marinescu, Bogdan Dorobat, Octavian Dragos Palade, Felicia Manole, Horia Muresian, Matei Popa-Cherecheanu and Cătălina Mariana Ciornei
J. Clin. Med. 2024, 13(12), 3515; https://doi.org/10.3390/jcm13123515 - 15 Jun 2024
Viewed by 403
Abstract
Congenital cervicofacial vascular anomalies are extremely rare and present many difficulties in diagnosis and treatment requiring a multidisciplinary approach. Firstly, there is little consensus on this subject among head and neck specialists. There are two main types of vascular anomalies: vascular tumors and [...] Read more.
Congenital cervicofacial vascular anomalies are extremely rare and present many difficulties in diagnosis and treatment requiring a multidisciplinary approach. Firstly, there is little consensus on this subject among head and neck specialists. There are two main types of vascular anomalies: vascular tumors and vascular malformations. Vascular malformations are also divided into malformations with slow blood flow (veins, lymphatics, capillaries or combined) and malformations with a fast blood flow (arteriovenous malformations and fistula). Vascular tumors like hemangiomas are known for their spontaneous involution with aging, while vascular malformations grow in dimensions with age. It is very important to choose the correct differential diagnosis between cervicofacial hemangiomas and vascular malformations for proper therapy management. Anamnesis and clinical exams help in raising suspicions about the real nature of a cervico-vascular anomaly. Furthermore, imaging brings in-depth details of the anomaly, ranging from ultrasound and contrast CT to MRI scanning and minimally invasive angiography. Angiography with selective embolization is rarely a curative procedure for arteriovenous malformations, being more suitable as a preliminary step before attempted surgical removal. Surgery is clearly necessary when there are aesthetic and functional deficits. Slow-flow vascular malformations present a reduced morbidity, and in cases without involution, the surgical ablation is reserved for the cases with aesthetic dysfunctions or psychological trauma. Lymphatic malformations must undergo surgical ablation when they are associated with mass effects and compression of great vessels or aerial viscera. The prognosis after surgical removal is good, with a low rate of recurrence or morbidity. Fast-flow vascular malformations require a combined approach, with embolization and excision in the next 48 h for safety reasons. Removal may be followed by reconstructive surgery depending on the location and dimensions of the malformation, with a possible secondary recovery of the normal microscopic vessels. Some of the masses may hinder the normal airflow and swallowing. Pathology is the gold standard for confirming the clinical and imaging diagnosis. Full article
(This article belongs to the Special Issue New Insights into Head and Neck Surgery)
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