Search for Articles:
Title / Keyword
Author / Affiliation / Email
Journal
Article Type
 
 
Advanced Search
 
Section
Special Issue
Volume
Issue
Number
Page
 
5.2
2.9
Journals
JCM
Special Issues
Clinical Advances in Minimally Invasive Spinal Treatment: 2nd Edition
jcm-logo
Submit to Special Issue Submit Abstract to Special Issue Review for JCM Propose a Special Issue

Journal Menu

► Journal Menu

Journal Browser

► Journal Browser
share announcement

Clinical Advances in Minimally Invasive Spinal Treatment: 2nd Edition

A special issue of Journal of Clinical Medicine (ISSN 2077-0383). This special issue belongs to the section "Orthopedics".

Deadline for manuscript submissions: 20 April 2026 | Viewed by 1460

Special Issue Editors

Dr. Akihiko Hiyama

E-Mail Website
Guest Editor
Department of Orthopaedic Surgery, Surgical Science, Tokai University School of Medicine, Isehara 259-1143, Japan
Interests: minimally invasive spine treatment; intraoperative image guidance surgery system; single position spine surgery; navigation-assisted lateral lumbar interbody fusion; molecular biology of Intervertebral discs
Special Issues, Collections and Topics in MDPI journals
Dr. Haruki Funao

E-Mail Website
Guest Editor
Department of Orthopaedic Surgery, School of Medicine, International University of Health and Welfare (IUHW), Chiba 286-0124, Japan
Interests: minimally invasive spinal treatment (MIST); minimally invasive spine stabilization (MISt); spinal deformity; spinal infection; navigation-guided spine surgery; trans-sacral canal plasty (TSCP)
Special Issues, Collections and Topics in MDPI journals
Dr. Masayuki Ishihara

E-Mail
Guest Editor
Department of Orthopedic Surgery, Kansai Medical University Hospital, Osaka 573-1191, Japan
Interests: adult spinal deformity; minimally invasive surgical techniques; spinal deformities

Special Issue Information

Dear Colleagues,

It is our pleasure to invite you to contribute to this Special Issue entitled “Clinical Advances in Minimally Invasive Spinal Treatment: 2nd Edition”. This is a new Special Issue that follows the nine papers we published in the first edition. For more details, please click on the following link: https://www.mdpi.com/journal/jcm/special_issues/6544PN0H2U.

The 2nd Edition of our Special Issue focuses on cutting-edge technologies and therapeutic strategies shaping the future of spine surgery and care. We invite original research, reviews, and clinical studies on robotic-assisted spinal surgery, artificial intelligence (AI), and machine learning (ML) for diagnosis, surgical planning, risk prediction, and postoperative outcomes. Particular attention will be given to the clinical utility of cement-augmented pedicle screws for osteoporotic spines, techniques to minimize cement leakage, and biomechanical innovations enhancing fixation strength. Furthermore, we encourage studies on pharmacological interventions for osteoporosis, including anabolic agents and novel combination therapies, and their impact on surgical outcomes and fracture prevention. By bridging engineering innovations, surgical techniques, and medical therapies, this Special Issue seeks to accelerate the translation of multidisciplinary advances into real-world clinical practice. We welcome contributions exploring novel technologies, and predictive analytics that will define the next era of spine surgery and patient care.

Dr. Akihiko Hiyama
Dr. Haruki Funao
Dr. Masayuki Ishihara
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 250 words) can be sent to the Editorial Office for assessment.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Journal of Clinical Medicine is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • robotic-assisted spine surgery
  • artificial intelligence (AI)
  • machine learning (ML)
  • cement-augmented pedicle screws
  • cement leakage risk stratification
  • osteoporosis pharmacotherapy
  • surgical navigation systems
  • image-guided spine surgery
  • predictive analytics in spine care
  • spine technology innovation

Benefits of Publishing in a Special Issue

  • Ease of navigation: Grouping papers by topic helps scholars navigate broad scope journals more efficiently.
  • Greater discoverability: Special Issues support the reach and impact of scientific research. Articles in Special Issues are more discoverable and cited more frequently.
  • Expansion of research network: Special Issues facilitate connections among authors, fostering scientific collaborations.
  • External promotion: Articles in Special Issues are often promoted through the journal's social media, increasing their visibility.
  • Reprint: MDPI Books provides the opportunity to republish successful Special Issues in book format, both online and in print.

Further information on MDPI's Special Issue policies can be found here.

Related Special Issue

Published Papers (2 papers)

Download All Papers
Order results
Result details
Show export options expand_more Show export options expand_less
Select all
Export citation of selected articles as:

Research

Jump to: Other

13 pages, 1014 KB  
Article
Cement Leakage in Cement-Augmented Fenestrated Pedicle Screws for Osteoporotic Spine: Risk Stratification with Quantitative Computed Tomography Analysis
by Akira Shinohara, Tomoaki Kanai, Shunsuke Katsumi, Shintaro Obata, Hiroki Wakiya, Takero Tsuzuki and Mitsuru Saito
J. Clin. Med. 2025, 14(22), 8178; https://doi.org/10.3390/jcm14228178 - 18 Nov 2025
Viewed by 837
Abstract
Background/Objectives: Cement-augmented fenestrated pedicle screws (CAFPSs) are widely used to enhance fixation strength in osteoporotic vertebrae; however, cement leakage remains a major concern because it can lead to severe complications. This study aimed to clarify the frequency, patterns, and risk factors of [...] Read more.
Background/Objectives: Cement-augmented fenestrated pedicle screws (CAFPSs) are widely used to enhance fixation strength in osteoporotic vertebrae; however, cement leakage remains a major concern because it can lead to severe complications. This study aimed to clarify the frequency, patterns, and risk factors of cement leakage using postoperative computed tomography (CT). Methods: A total of 302 screws placed in 79 osteoporotic patients who underwent spinal fixation with CAFPSs between March 2022 and December 2024 were retrospectively analyzed. Cement leakage was evaluated using postoperative CT, and risk factors were examined by logistic regression and receiver operating characteristic (ROC) curve analysis. Results: Cement leakage was observed in 46 patients (58.2%) and 71 screws (23.5%), but no severe complications such as symptomatic pulmonary embolism occurred. Multivariate analysis identified right-sided screw insertion (OR = 2.498, 95% CI: 1.270–4.913, p = 0.008) and shorter lateral cortical wall distance (OR = 0.547, 95% CI: 0.469–0.638, p < 0.001) as independent risk factors. ROC curve analysis demonstrated high predictive accuracy for lateral cortical wall distance (area under the curve = 0.842), with a cutoff value of 9.21 mm (sensitivity = 0.845; specificity = 0.719). Cement leakage occurred significantly more frequently in the thoracic spine than in the lumbar spine (34.2% vs. 17.0%, p < 0.001). Conclusions: Right-sided screw insertion and shorter lateral cortical wall distance were identified as major risk factors for cement leakage with CAFPSs. Quantitative CT-based assessment may contribute to risk stratification and optimization of screw placement planning to improve surgical safety. Full article
(This article belongs to the Special Issue Clinical Advances in Minimally Invasive Spinal Treatment: 2nd Edition)
►▼ Show Figures

Figure 1

Other

Jump to: Research

10 pages, 5311 KB  
Technical Note
Exoscopic Minimally Invasive Open-Door Laminoplasty with Pedicle Screw Fixation for Cervical Ossification of the Posterior Longitudinal Ligament: A Technical Note and Preliminary Clinical Experience
by Kentaro Yamane, Wataru Narita, Shinichiro Takao, Hisakazu Shitozawa, Kazuhiro Takeuchi and Shinnosuke Nakahara
J. Clin. Med. 2026, 15(6), 2307; https://doi.org/10.3390/jcm15062307 - 18 Mar 2026
Viewed by 273
Abstract
Background: Posterior decompression with instrumented fusion (PDF) is a conventional surgical procedure performed in patients with massive ossification of the posterior longitudinal ligament (OPLL); however, it is invasive to the posterior cervical tissues. In this report, we introduce a novel PDF technique, [...] Read more.
Background: Posterior decompression with instrumented fusion (PDF) is a conventional surgical procedure performed in patients with massive ossification of the posterior longitudinal ligament (OPLL); however, it is invasive to the posterior cervical tissues. In this report, we introduce a novel PDF technique, exoscopic minimally invasive open-door laminoplasty with pedicle screw fixation (exLAPPS), to treat cervical OPLL, while minimizing posterior tissue damage. Methods: ExLAPPS was indicated for patients with K-line (−) OPLL or a canal occupying a ratio of ≥50%, allowing decompression from C3 to C7. A small midline incision was used for the navigation reference placement and exoscopic minimally invasive open-door laminoplasty, whereas bilateral lateral incisions were utilized for posterior fixation, including pedicle screw insertion, based on the minimally invasive cervical pedicle screw technique. Results: A total of 7 patients with K-line (-) or a canal occupancy ≥50% underwent exLAPPS for cervical OPLL. The mean operative time was 248 min (range, 165–342 min) and the mean blood loss was 320 mL (range, 50–740 mL). Postoperative imaging demonstrated adequate spinal cord decompression in all patients. A total of 52 pedicle screws were inserted, with a pedicle screw deviation rate of 1.9%. Conclusions: ExLAPPS is a minimally invasive surgical technique designed for posterior decompression and fixation in patients with cervical OPLL. In this preliminary case series, the procedure was successfully performed with acceptable operative time, blood loss, and screw placement accuracy. Although the present study did not include a direct comparison with conventional procedures, these preliminary observations suggest that ExLAPPS is a feasible surgical option for selected patients with cervical OPLL. Full article
(This article belongs to the Special Issue Clinical Advances in Minimally Invasive Spinal Treatment: 2nd Edition)
►▼ Show Figures

Figure 1

Show export options expand_more Show export options expand_less
Select all
Export citation of selected articles as:
 
Displaying articles 1-2
Back to TopTop