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Anterior Cruciate Ligament (ACL) Injuries: Clinical Treatment and Rehabilitation
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Anterior Cruciate Ligament (ACL) Injuries: Clinical Treatment and Rehabilitation

A special issue of Journal of Clinical Medicine (ISSN 2077-0383). This special issue belongs to the section "Orthopedics".

Deadline for manuscript submissions: 25 September 2025 | Viewed by 495

Special Issue Editor

Dr. Young-Jin Seo

E-Mail Website
Guest Editor
Department of Orthopaedic Surgery, Dongtan Sacred Heart Hospital, Hallym University College of Medicine, Hwaseong, Republic of Korea
Interests: orthopedic surgery; anterior cruciate ligament reconstruction; osteotomy; knee; bone graft

Special Issue Information

Dear Colleagues,

Anterior cruciate ligament (ACL) injuries remain a prevalent challenge, particularly in athletic populations. Advances in clinical treatment and rehabilitation have transformed outcomes, but challenges persist. ACL reconstruction has seen significant technical evolution, emphasizing precision, durability, and optimized recovery. Innovations like lateral extra-articular procedures, all-inside techniques, internal bracing, slope reducing osteotomy, and biologic augmentation promise to enhance healing, graft integration, and biomechanical stability.

Rehabilitation plays a critical role in recovery and long-term success. A growing focus on injury prevention through neuromuscular training programs has demonstrated efficacy in reducing ACL injury rates, particularly in young athletes. However, addressing psychological readiness, particularly fear of reinjury, remains a vital yet underexplored dimension of recovery.

A multidisciplinary approach, combining surgical, rehabilitative, and preventive strategies, is essential for optimizing outcomes and reducing the long-term burden of ACL injuries.

This Special Issue aims to provide a thorough exploration of the challenges and advancements in clinical treatment and rehabilitation for ACL injuries. By featuring contributions from experts, it emphasizes clinical progress and long-term recovery outcomes, offering valuable knowledge to advance both research and practice.

Dr. Young-Jin Seo
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Journal of Clinical Medicine is an international peer-reviewed open access semimonthly journal published by MDPI.

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Keywords

  • anterior cruciate ligament (ACL)
  • reconstruction
  • lateral extra-articular procedures
  • all-inside technique
  • internal bracing
  • slope reducing osteotomy
  • biologic augmentation
  • rehabilitation

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Published Papers (1 paper)

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17 pages, 3381 KiB  
Systematic Review
Combined Anterior Cruciate Ligament and Anterolateral Ligament Reconstruction Shows Reduced Graft Failure Rates and Superior Residual Rotational Stability Regardless of Anterolateral Ligament Reconstruction Graft: A Systematic Review
by Joo Hyung Han, Sung-Hwan Kim, Min Jung, Hyun-Soo Moon and Kwangho Chung
J. Clin. Med. 2025, 14(7), 2237; https://doi.org/10.3390/jcm14072237 - 25 Mar 2025
Viewed by 299
Abstract
Objectives: The aim of this study is to evaluate the literature for comparing clinical outcomes of anterior cruciate ligament reconstruction (ACLR) with concomitant anterolateral ligament reconstruction (ALLR) versus isolated ACLR, with a primary focus on analyzing differences in outcomes based on the [...] Read more.
Objectives: The aim of this study is to evaluate the literature for comparing clinical outcomes of anterior cruciate ligament reconstruction (ACLR) with concomitant anterolateral ligament reconstruction (ALLR) versus isolated ACLR, with a primary focus on analyzing differences in outcomes based on the type of graft used for ALLR. Methods: We identified comparative studies involving primary ACLR performed in conjunction with ALLR. Graft failure rates, residual pivot shift, residual anterior–posterior (AP) laxity at follow-up, and patient-reported outcome measures were determined. Variables associated with isolated ACLR and ACLR combined with ALLR were compared based on the type of graft used for ALLR. Results: This systematic review included nine studies involving 2740 patients. Combined ACLR with ALLR using hamstring tendon (HT) autografts or tibialis allografts showed lower graft failure rates than isolated ACLR (HT autograft: rate, 0–5.9%, odds ratio [OR], 2.16–12.91; tibialis allograft: rate, 0%, OR, 2.00–5.27). Similarly, the combined procedure showed reduced residual pivot shift rates (HT autograft: rate, 0–9.1%, OR, 2.00–12.16; tibialis allograft: rate, 0%, OR, 7.65–15.33) compared to isolated ACLR. Residual AP laxity and patient-reported outcomes were similar or more favorable for the combined procedure; however, the results were heterogeneous. Complications related to the type of graft used for ALLR or the presence of ALLR itself were not reported. Conclusions: Regardless of the graft type used for ALLR, the combination of ACLR with ALLR showed better clinical outcomes, including reduced graft failure rates and superior residual rotational stability compared to isolated ACLR. However, the high heterogeneity observed across studies suggests that these findings should be interpreted with caution, and further research is needed to draw more definitive conclusions. Full article
(This article belongs to the Special Issue Anterior Cruciate Ligament (ACL) Injuries: Clinical Treatment and Rehabilitation)
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