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Clinical Advances in Colorectal Cancer
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Clinical Advances in Colorectal Cancer

A special issue of Journal of Clinical Medicine (ISSN 2077-0383). This special issue belongs to the section "Gastroenterology & Hepatopancreatobiliary Medicine".

Deadline for manuscript submissions: 31 August 2024 | Viewed by 697

Special Issue Editor

Prof. Dr. Laith Alrubaiy

E-Mail Website
Guest Editor
School of Medicine, Swansea University, Swansea SA2 8PP, UK
Interests: colorectal cancer; colon cancer; artificial intelligence; colonoscopy; cancer screening
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

Over the recent decades, there has been many advancements in colorectal cancer research and a significant investment in research aimed at better the diagnosis, screening and treatment for this disease. This has helped improve the surveillance and understanding of the disease progression, with potential direct clinical benefits in prevention and early treatment, especially screening programs. At the same time, there are several challenges that arise with the full implementation of endoscopy screening programs and technology in countries with limited resources, leading to the inequality of care provided to patients.

This Special Issue of the Journal of Clinical Medicine aims to highlight the current state of clinical research and practice in colorectal cancer, and showcase some of the most cutting-edge technologies and advancements in the field to enhance the care provided to patients. It will also cover the challenges of properly implementing endoscopy practice in resource-constrained settings.

Prof. Dr. Laith Alrubaiy
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Journal of Clinical Medicine is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • colorectal cancer
  • colon cancer
  • colonic polyps
  • colonoscopy
  • cancer screening

Published Papers (1 paper)

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Research

9 pages, 496 KiB  
Article
Primary Tumor Sidedness Associated with Clinical Characteristics and Postoperative Outcomes in Colon Cancer Patients: A Propensity Score Matching Analysis
by Wan-Hsiang Hu, Samuel Eisenstein, Lisa Parry and Sonia Ramamoorthy
J. Clin. Med. 2024, 13(13), 3654; https://doi.org/10.3390/jcm13133654 - 22 Jun 2024
Viewed by 464
Abstract
Background: Recent investigations have suggested that-sidedness is associated with the prognosis of colon cancer patients. However, the role of sidedness in surgical outcome is unclear. In this study, we tried to demonstrate the real role of sidedness in postoperative results for colon cancer [...] Read more.
Background: Recent investigations have suggested that-sidedness is associated with the prognosis of colon cancer patients. However, the role of sidedness in surgical outcome is unclear. In this study, we tried to demonstrate the real role of sidedness in postoperative results for colon cancer patients receiving surgical intervention. Methods: This is a propensity score matching study using the database of the American College of Surgeons-National Surgical Quality Improvement Program (ACS-NSQIP) from 2009 to 2013. Sidedness groups including right-sided and left-sided colon cancer were created according to the associated diagnosis and procedure codes. Postoperative 30-day mortality, morbidity, overall complications, and total length of hospital stay were analyzed after performing propensity score matching. Results: Out of a total of 24,436 colon cancer patients who received associated operations, 15,945 patients had right-sided cancer and 8941 patients had left-sided cancer. Right-sided colon cancer patients were accompanied by more preoperative comorbidities including old age, female sex, hypertension, dyspnea, anemia, hypoalbuminemia, and a high American Society of Anesthesiologists grade (SMD > 0.1). Postoperative mortality, morbidities including re-intubation, bleeding, urinary tract infection and deep vein thrombosis, postoperative overall complications, and total length of hospital stay were significantly associated with right-sided cancer (p < 0.05). After 1:1 propensity score matching, postoperative mortality was not significantly different between right-sided cancer (2.3%) and left-sided cancer (2.4%) patients. The patients with left-sided colon cancer had significantly more postoperative morbidities, more overall complications, and longer total length of hospital stay. Conclusions: Poor clinical characteristics and postoperative outcomes were noted in right-sided cancer patients. After propensity score matching, left-sided cancer patients had worse postoperative outcomes than those with right-sided cancer. Full article
(This article belongs to the Special Issue Clinical Advances in Colorectal Cancer)
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