New Insights into Pancreatic Surgery

A special issue of Journal of Clinical Medicine (ISSN 2077-0383). This special issue belongs to the section "Gastroenterology & Hepatopancreatobiliary Medicine".

Deadline for manuscript submissions: 30 September 2024 | Viewed by 112

Special Issue Editors


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Guest Editor
Division of HPB Surgery & Liver Transplantation, Hospital Universitario Virgen de las Nieves, Granada, Spain
Interests: pancreatic cancer; pancreatic cystic tumors; IPMN; IPNB; acute pancreatitis; chronic pancreatitis; cholangiocarcinoma; hepatocellular carcinoma; liver metastases; liver transplantation; minimally invasive surgery

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Guest Editor
Servicio de Cirugía General, Hospital General Universitario Dr. Balmis, Alicante, Spain
Interests: pancreatic cancer; pancreatic cystic tumors; IPMN; IPNB; acute pancreatitis; chronic pancreatitis; cholangiocarcinoma; hepatocellular carcinoma; liver metastases; liver transplantation; minimally invasive surgery

Special Issue Information

Dear Colleagues,

The number of pancreatic surgeries is increasing every year. There are several reasons, but the most remarkable are the increase in diagnosed pancreatic cancers and the more frequent diagnosis of other pancreatic diseases for which surgery is now considered as an option due to their possibility of malignancy transformation. This has meant that surgical indications have expanded steadily. The main problems facing pancreatic surgery are the high incidence of postoperative major complications and the low but remarkable mortality. The centralization in high-volume centers; technical advances, such as minimally invasive surgery approaches, including robotic surgery; and the standardization of surgical procedures have decreased the complication rates. However, more complex cases (patients with arterial involvement or neoadjuvant chemotherapy) are evaluated daily. Surgeons had also implemented several healthcare tools to measure and improve surgical results (textbook outcomes, failure to rescue, benchmarking, fistula risk scores, etc.). In this Special Issue, we invite authors to submit papers about all surgical topics that allow readers to increase their knowledge about treating patients with pancreatic surgical diseases.

Prof. Dr. Mario Serradilla-Martín
Prof. Dr. José Manuel Ramia
Guest Editors

Manuscript Submission Information

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Keywords

  • pancreas
  • pancreatectomy
  • surgery
  • outcomes
  • cancer
  • fistula
  • minimally invasive surgery
  • IPMT

Published Papers (1 paper)

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Research

13 pages, 573 KiB  
Article
A Comparison of Preoperative Predictive Scoring Systems for Postoperative Pancreatic Fistula after Pancreaticoduodenectomy Based on a Single-Center Analysis
by Naomi Verdeyen, Filip Gryspeerdt, Luìs Abreu de Carvalho, Pieter Dries and Frederik Berrevoet
J. Clin. Med. 2024, 13(11), 3286; https://doi.org/10.3390/jcm13113286 (registering DOI) - 3 Jun 2024
Abstract
Background: Postoperative pancreatic fistula (POPF) after pancreaticoduodenectomy (PD) is associated with major postoperative morbidity and mortality. Several scoring systems have been described to stratify patients into risk groups according to the risk of POPF. The aim of this study was to compare [...] Read more.
Background: Postoperative pancreatic fistula (POPF) after pancreaticoduodenectomy (PD) is associated with major postoperative morbidity and mortality. Several scoring systems have been described to stratify patients into risk groups according to the risk of POPF. The aim of this study was to compare scoring systems in patients who underwent a PD. Methods: A total of 196 patients undergoing PD from July 2019 to June 2022 were identified from a prospectively maintained database of the University Hospital Ghent. After performing a literature search, four validated, solely preoperative risk scores and the intraoperative Fistula Risk Score (FRS) were included in our analysis. Furthermore, we eliminated the variable blood loss (BL) from the FRS and created an additional score. Univariate and multivariate analyses were performed for all risk factors, followed by a ROC analysis for the six scoring systems. Results: All scores showed strong prognostic stratification for developing POPF (p < 0.001). FRS showed the best predictive accuracy in general (AUC 0.862). FRS without BL presented the best prognostic value of the scores that included solely preoperative variables (AUC 0.783). Soft pancreatic texture, male gender, and diameter of the Wirsung duct were independent prognostic factors on multivariate analysis. Conclusions: Although all predictive scoring systems stratify patients accurately by risk of POPF, preoperative risk stratification could improve clinical decision-making and implement preventive strategies for high-risk patients. Therefore, the preoperative use of the FRS without BL is a potential alternative. Full article
(This article belongs to the Special Issue New Insights into Pancreatic Surgery)
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