Sepsis: New Insights into Diagnosis and Treatment
A special issue of Journal of Clinical Medicine (ISSN 2077-0383). This special issue belongs to the section "Infectious Diseases".
Deadline for manuscript submissions: 27 February 2025 | Viewed by 11
Special Issue Editors
Interests: sepsis; continuous renal replacement therapy; blood purification; ultrasound; adjuvant therapy; ARDS; nutrition; infection disease
Special Issue Information
Dear Colleagues,
Sepsis represents a life-threatening condition with a huge impact on health care costs. Further, Sepsis is a “time-dependent” disease; the outcome is highly influenced by the prompt detection and efficiency of the management, even from the very “first hour”. Due to the centrality of the complex interactions between the infectious insult and the host's immune response, a deeper understanding of the mechanisms involved in the dysregulation host response is mandatory.
Interestingly, It is now clear that the individual genomic profile is partly responsible for the interindividual variability of the clinical evolution of sepsis. In light of this evidence, immunomorinitoring and immunotherapy have gained increasing recognition in recent decades. Unfortunately, until now, evidence has not supported the extensive introduction of adjuvant therapy in current clinical practice.
In this Special Issue, we invite researchers and clinicians to submit their work, including original clinical research studies, meta-analyses, and systematic reviews, that will provide additional insight on the diagnosis and treatment of septic shock.
Dr. Francesco Forfori
Dr. Etrusca Brogi
Guest Editors
Manuscript Submission Information
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Keywords
- sepsis and sepsis subphenotypes
- adjuvant therapy
- blood purification strategies
- immunomonitoring and immunotherapy
- the microbiome in sepsis
- crosstalk in multi-organ failure (MOF)
- ultrasound in sepsis (POCUS)
- sepsis-induced coagulophaty and DIC
- antibiotic therapy
- multimodal approaches to surgical source control
