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Special Issues
Cardiogenic Shock — Current Concepts and Improving Outcomes
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Cardiogenic Shock — Current Concepts and Improving Outcomes

A special issue of Journal of Clinical Medicine (ISSN 2077-0383). This special issue belongs to the section "Cardiovascular Medicine".

Deadline for manuscript submissions: closed (25 February 2024) | Viewed by 739

Special Issue Editor

Prof. Dr. Konstantinos Karatolios

E-Mail Website
Guest Editor
Department of Cardiology, Philipps-University Marburg, Baldinger Str., 35037 Marburg, Germany
Interests: cardiogenic shock; cardiac arrest; interventional cardiology; heart failure; acute cardiac care
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

The management of cardiogenic shock (CS) remains challenging despite the available treatment options. Furthermore, only a few therapeutic interventions have been shown to clearly improve the prognosis and outcomes of CS. Significant areas of uncertainty still remain, particular regarding risk stratification, the use of mechanical circulatory support and medical therapies for these complex conditions in patients. Therefore, in order to improve patients outcomes, research is urgently needed that addresses the substantial knowledge gaps in the management of CS.

In this Special Issue, we aim to collect original research and review articles that focus on:

  • Prognosis and risk stratification in CS;
  • Cardiac arrest and CS;
  • The roles of medical therapies and mechanical circulatory support in CS;
  • Evolving therapies in CS.

Prof. Dr. Konstantinos Karatolios
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Journal of Clinical Medicine is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • cardiogenic shock
  • cardiac arrest
  • risk stratification
  • mechanical circulatory support
  • medical therapies

Published Papers (1 paper)

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Research

16 pages, 1114 KiB  
Article
Comparative Analysis of Therapeutic Strategies in Post-Cardiotomy Cardiogenic Shock: Insight into a High-Volume Cardiac Surgery Center
by B. Ufuk Baldan, Romy R. M. J. J. Hegeman, Nelleke M. J. P. Bos, Hans G. Smeenk, Robert J. M. Klautz and Patrick Klein
J. Clin. Med. 2024, 13(7), 2118; https://doi.org/10.3390/jcm13072118 - 5 Apr 2024
Viewed by 420
Abstract
Background: Post-cardiotomy cardiogenic shock (PCCS), which is defined as severe low cardiac output syndrome after cardiac surgery, has a mortality rate of up to 90%. No study has yet been performed to compare patients with PCCS treated by conservative means to patients [...] Read more.
Background: Post-cardiotomy cardiogenic shock (PCCS), which is defined as severe low cardiac output syndrome after cardiac surgery, has a mortality rate of up to 90%. No study has yet been performed to compare patients with PCCS treated by conservative means to patients receiving additional mechanical circulatory support with veno-arterial extracorporeal membrane oxygenation (ECMO). Methods: A single-center retrospective analysis from January 2018 to June 2022 was performed. Results: Out of 7028 patients who underwent cardiac surgery during this time period, 220 patients (3%) developed PCCS. The patients were stratified according to their severity of shock based on the Stage Classification Expert Consensus (SCAI) group. Known risk factors for shock-related mortality, including the vasoactive–inotropic score (VIS) and plasma lactate levels, were assessed at structured intervals. In patients treated additionally with ECMO (n = 73), the in-hospital mortality rate was 60%, compared to an in-hospital mortality rate of 85% in patients treated by conservative means (non-ECMO; n = 52). In 18/73 (25%) ECMO patients, the plasma lactate level normalized within 48 h, compared to 2/52 (4%) in non-ECMO patients. The morbidity of non-ECMO patients compared to ECMO patients included a need for dialysis (42% vs. 60%), myocardial infarction (19% vs. 27%), and cerebrovascular accident (17% vs. 12%). Conclusions: In conclusion, the additional use of ECMO in PCCS holds promise for enhancing outcomes in these critically ill patients, more rapid improvement of end-organ perfusion, and the normalization of plasma lactate levels. Full article
(This article belongs to the Special Issue Cardiogenic Shock — Current Concepts and Improving Outcomes)
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