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Cataract and Refractive Surgery and Intraocular Lens Implantation: Clinical Advances and Perspectives

A special issue of Journal of Clinical Medicine (ISSN 2077-0383). This special issue belongs to the section "Ophthalmology".

Deadline for manuscript submissions: 15 December 2025 | Viewed by 932

Special Issue Editor


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Guest Editor
Department of Experimental Physiology and Pathophysiology, Medical University of Warsaw, 01-756 Warsaw, Poland
Interests: intraocular lens power calculation; cataract surgery; intraocular lens design; EDoF IOLs; multifocal IOLs

Special Issue Information

Dear Colleagues,

Cataract surgery remains one of the most commonly performed and highly successful procedures in modern ophthalmology. Over the past few decades, advancements in surgical techniques, intraocular lens (IOL) technology, and perioperative management have significantly improved patient outcomes, enhancing both safety and visual quality. This Special Issue explores the latest innovations, challenges, and future directions in cataract surgery and IOL development.

Key topics covered in this issue include the following:

  1. Modern Surgical Techniques
    • Advances in phacoemulsification technology and femtosecond laser-assisted cataract surgery
    • Innovations in small-incision cataract surgery (SICS) and micro-incision techniques
    • Evolving strategies for complex cases, including dense cataracts and coexisting ocular conditions
  2. Next-Generation Intraocular Lenses
    • New IOL materials and surface coatings to improve biocompatibility and reduce complications
    • Multifocal, extended depth of focus (EDOF), and accommodating IOLs for enhanced visual outcomes
    • Customizable and light-adjustable IOLs for postoperative refractive fine-tuning
  3. Optimizing Visual Outcomes
    • Advances in biometry and IOL power calculation formulas for improved refractive accuracy
    • Management of residual refractive errors and astigmatism correction with Toric IOLs
    • Patient-reported outcomes and quality-of-life improvements following cataract surgery
  4. Perioperative and Postoperative Management
    • Strategies to prevent and manage intraoperative complications
    • Innovations in postoperative care, including anti-inflammatory regimens and novel drug delivery systems
    • Long-term IOL performance, posterior capsule opacification (PCO) prevention, and secondary interventions
  5. Future Perspectives in Cataract Surgery
    • Artificial intelligence and machine learning applications in surgical planning and outcome prediction
    • Robotics and automation in cataract surgery
    • Potential impact of gene therapy and regenerative medicine in lens restoration

This Special Issue provides a comprehensive review of the latest developments in cataract surgery and intraocular lenses, offering valuable insights for ophthalmic surgeons, researchers, and industry professionals. By bridging current research with clinical practice, we aim to highlight the evolving landscape of cataract treatment and pave the way for future innovations that enhance patient care.

Dr. Janusz Skrzypecki
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Journal of Clinical Medicine is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • cataract surgery
  • intraocular lens power calculation
  • intraocular lenses
  • EDoF IOL
  • multifocal IOL
  • monofocal IOL
  • laser refractive surgery

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Published Papers (1 paper)

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Research

17 pages, 1917 KB  
Article
Visual Outcomes of a Non-Diffractive Extended Depth-of-Focus Intraocular Lens in Patients with Early-Stage Age-Related Macular Degeneration
by Emilio Dorronzoro-Ramirez, Miguel Angel Sanchez-Tena, Cristina Alvarez-Peregrina, Jose Miguel Cardenas Rebollo, Dayan Flores Cervantes and Celia Sánchez-Ramos
J. Clin. Med. 2025, 14(17), 5953; https://doi.org/10.3390/jcm14175953 - 23 Aug 2025
Viewed by 314
Abstract
Background/Objectives: Age-related macular degeneration (AMD) is a leading cause of visual impairment in older adults and often coexists with cataracts. The indication of presbyopia-correcting intraocular lenses (IOLs) in these patients remains controversial. This study aimed to evaluate the clinical performance of a [...] Read more.
Background/Objectives: Age-related macular degeneration (AMD) is a leading cause of visual impairment in older adults and often coexists with cataracts. The indication of presbyopia-correcting intraocular lenses (IOLs) in these patients remains controversial. This study aimed to evaluate the clinical performance of a non-diffractive extended depth-of-focus (EDOF) IOL (LuxSmart™) compared to a monofocal plus IOL (Tecnis Eyhance™) in cataract patients with early-stage dry AMD. Methods: In this prospective observational study, 41 patients with early-stage AMD underwent bilateral cataract surgery with either LuxSmart™ or Tecnis Eyhance™ IOL implantation, targeting postoperative emmetropia. The eye selected for analysis was the first eye scheduled for surgery. Preoperative and postoperative evaluations included high and low-contrast distance visual acuity, intermediate and near visual acuity, defocus curves, ocular light scatter (halometry), and quality of life assessment (NEI VFQ-25). Postoperative biometric accuracy and refractive outcomes were also analyzed. Results: Both IOLs showed high refractive accuracy, with 100% of eyes within ±0.50 D of target. Postoperative uncorrected distance visual acuity was 0.10 ± 0.06 LogMAR for Eyhance and 0.07 ± 0.02 for LuxSmart (p = 0.06). Low contrast VA at 20% was 0.22 ± 0.11 (Eyhance) and 0.26 ± 0.16 (LuxSmart) (p = 0.49). Depth of focus was approximately 1.75 D for both lenses. Light scatter (LDI) improved postoperatively in both groups with no significant differences (p = 0.54). VFQ-25 scores showed improvement in daily activities, though no changes were observed in driving or mental health domains. Conclusions: Both lenses are safe and effective options for early AMD patients undergoing cataract surgery, providing good functional vision at multiple distances Full article
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