Interaction Between Systemic Diseases and Oral Diseases
A special issue of Journal of Clinical Medicine (ISSN 2077-0383). This special issue belongs to the section "Dentistry, Oral Surgery and Oral Medicine".
Deadline for manuscript submissions: 31 March 2025 | Viewed by 1868
Special Issue Editor
Special Issue Information
Dear Colleagues,
Many systemic diseases affect oral health, either directly or as a result of medical treatment. Conversely, the condition of the mouth can affect the functioning of other parts of the human body. Although many such interactions between systemic diseases and oral diseases have already been described, the underlying pathophysiological causes of these interactions remain unclear. In addition, many potential interactions between internal organs and the oral cavity have not yet been investigated. Therefore, this Special Issue of JCM aims to compile studies on the interaction between systemic diseases and oral diseases, and to contribute to enhanced communication between the medical and dental disciplines, which often still function independently of each other.
Dr. Henk S. Brand
Guest Editor
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Keywords
- medical dental interaction
- saliva
- xerostomia
- diagnostics
- inflammatory bowel disease
- cancer survivors
- dental erosion
- Sjögren’s disease
- liver transplantation
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Planned Papers
The below list represents only planned manuscripts. Some of these manuscripts have not been received by the Editorial Office yet. Papers submitted to MDPI journals are subject to peer-review.
Title: Treatment of dental inflammatory lesions: effects on the laboratory parameters in patients with hyperlipidemia: a clinical interventional study
Authors: Renata Martos; Mariann Harangi; Judit Szabó; Anett Földvári; János Sándor; Éva Katona; Ildikó Tar; György Paragh; Csongor Kiss; Ildikó Márton
Affiliation: Department of Operative Dentistry and Endodontics, Faculty of Dentistry, University Debrecen 4032 Debrecen, Nagyerdei krt 98. Hungary
Abstract: Background: Patients with hyperlipidemia are in the focus of interest because of a possible interplay between chronic local oral infections and hyperlipidemia resulting in a higher risk of cardiovascular diseases. This interventional clinical follow-up study aimed to evaluate oral/dental inflammatory status of hyperlipidemic patients receiving lipid-lowering therapy at least 6 months and the effects of non-surgical and surgical dental treatments /combined periodontal, endodontic, and dentoalveolar surgical treatments/ on oral health, serum CRP level and lipid markers related to cardiovascular risk.
Methods: All patients and controls underwent dental examination (clinical examination, X-ray, microbial examination of sub- and supragingival plaque samples) followed by combined therapy of periodontal, endodontic, and dentoalveolar surgical treatments in the patient group. Serum CRP and lipid parameters were checked on admission, 1-week, and 3-months, sub- and supragingival plaque samples were checked on admission and 3-months after finishing dental treatments. Changes in the patients’ findings during treatment were evaluated by one-way repeated measures ANOVA. Mean values of patients’ results were compared by paired t-test. The patients’ and healthy controls’ mean values were tested by independent t-test. If parametric approaches could not have been applied then non-parametric tests were used. The association between the occurrences of pathogenic vs. non-pathogenic flora in plaque samples was investigated by chi-square test.
Results: At 3-months the clinical periodontal characteristics of patients, including plaque index, gingival index and periodontal probing depth decreased significantly (p
