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Aortic Diseases and Complications: Diagnosis and Treatment
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Aortic Diseases and Complications: Diagnosis and Treatment

A special issue of Journal of Clinical Medicine (ISSN 2077-0383). This special issue belongs to the section "Cardiovascular Medicine".

Deadline for manuscript submissions: closed (15 February 2024) | Viewed by 3648

Special Issue Editor

Prof. Dr. Alexis Jacquier

E-Mail Website
Guest Editor
Department of Radiology, Timone Hospital, Assistance Publique-Hôpitaux de Marseille, 13005 Marseille, France
Interests: aortic diseases; aortic dissection; aortic aneurysm; complications; coronary artery disease; transcatheter aortic valve implantation

Special Issue Information

Dear Colleagues,

This Special Issue, "Aortic Diseases and Complications: Diagnosis and Treatment", presents the latest research on the diagnosis and treatmeny management of aortic diseases and their complications. The Special Issue covers key themes, including aortic aneurysms, dissections, and valve disorders, and focuses on the latest diagnostic techniques, imaging post-processing, and open surgical or endovascular interventions. The papers also discuss the challenges of managing aortic diseases in high-risk Marfan syndrome and associated diseases.

The research in this Special Issue emphasizes the need for early detection and intervention to prevent complications and improve patient outcomes. The papers presented here contribute significantly to the advancement of knowledge in the field of aortic diseases and provide valuable insights for clinicians and researchers alike.

With this Special Issue, we want to provide a platform for scientists to publish their new scientific findings in the area of aortic diseases and complications to further progress this important topic in the field of diagnostics and therapy.

Prof. Dr. Alexis Jacquier
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Journal of Clinical Medicine is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • aortic diseases
  • diagnosis
  • treatment
  • complications
  • management
  • high-risk patients
  • outcomes

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Further information on MDPI's Special Issue polices can be found here.

Published Papers (3 papers)

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Research

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13 pages, 930 KiB  
Article
Myocardial Injury after Non-Cardiac Surgery in Patients Who Underwent Open Repair for Abdominal Aortic Aneurysm: A Retrospective Study
by Myung Il Bae, Tae-Hoon Kim, Hei Jin Yoon, Suk-Won Song, Narhyun Min, Jongyun Lee and Sung Yeon Ham
J. Clin. Med. 2024, 13(4), 959; https://doi.org/10.3390/jcm13040959 - 7 Feb 2024
Cited by 1 | Viewed by 1257
Abstract
Background: Myocardial injury after non-cardiac surgery (MINS) has been known to be associated with mortality in various surgical patients; however, its prognostic role in abdominal aortic aneurysm (AAA) open repair remains underexplored. This study aimed to investigate the role of MINS as a [...] Read more.
Background: Myocardial injury after non-cardiac surgery (MINS) has been known to be associated with mortality in various surgical patients; however, its prognostic role in abdominal aortic aneurysm (AAA) open repair remains underexplored. This study aimed to investigate the role of MINS as a predictor of mortality in patients who underwent AAA open repair. Methods: This retrospective study investigated 352 patients who underwent open repair for non-ruptured AAA. The predictors of 30-day and 1-year mortalities were investigated using logistic regression analysis. Results: MINS was diagnosed in 41% of the patients after AAA open repair in this study. MINS was an independent risk factor of 30-day mortality (odds ratio [OR]: 10.440, 95% confidence interval [CI]: 1.278–85.274, p = 0.029) and 1-year mortality (OR: 5.189, 95% CI: 1.357–19.844, p = 0.016). Kaplan–Meier survival curves demonstrated significantly lower overall survival rates in patients with MINS compared to those without MINS (p = 0.003). Conclusion: This study revealed that MINS is a common complication after AAA open repair and is an independent risk factor of 30-day and 1-year mortalities. Patients with MINS have lower overall survival rates than those without MINS. Full article
(This article belongs to the Special Issue Aortic Diseases and Complications: Diagnosis and Treatment)
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16 pages, 1735 KiB  
Article
In Marfan Syndrome and Related Diseases, STABILISE Technique Should Be Used with Care: Results from a Volumetric Comparative Study of Endovascular Treatment for Aortic Dissection
by Ron Azogui, Alizee Porto, Maxime Castelli, Virgile Omnes, Mariangela De Masi, Michel Bartoli, Philippe Piquet, Vlad Gariboldi, Tiffany Busa, Alexis Jacquier, Laurence Bal and Marine Gaudry
J. Clin. Med. 2023, 12(13), 4378; https://doi.org/10.3390/jcm12134378 - 29 Jun 2023
Cited by 1 | Viewed by 1068
Abstract
Objectives: Aortic dissection in patients with Marfan and related syndromes (HTAD) is a serious pathology whose treatment by thoracic endovascular repair (TEVAR) is still under debate. The aim of this study was to assess the results of the TEVAR for aortic dissection in [...] Read more.
Objectives: Aortic dissection in patients with Marfan and related syndromes (HTAD) is a serious pathology whose treatment by thoracic endovascular repair (TEVAR) is still under debate. The aim of this study was to assess the results of the TEVAR for aortic dissection in patients with HTAD as compared to a young population without HTAD. Methods: The study received the proper ethical oversight. We performed an observational exposed (confirmed HTAD) vs. non-exposed (<65 years old) study of TEVAR-treated patients. The preoperative, 1 year, and last available CT scans were analyzed. The thoracic and abdominal aortic diameters, aortic length, and volumes were measured. The entry tears and false lumen (FL) status were assessed. The demographic, clinical, and anatomic data were collected during the follow-up. Results: Between 2011 and 2021, 17 patients were included in the HTAD group and 22 in the non-HTAD group. At 1 year, the whole aortic volume increased by +21.2% in the HTAD group and by +0.2% the non-HTAD groups, p = 0.005. An increase in the whole aortic volume > 10% was observed in ten cases (58.8%) in the HTAD group and in five cases (22.7%) in the non-HTAD group (p = 0.022). FL thrombosis was achieved in nine cases (52.9%) in the HTAD group vs. twenty (90.9%) cases in the non-HTAD group (p < 0.01). The risk factors for unfavorable anatomical evolution were male gender and the STABILISE technique. With a linear model, we observed a significantly different aortic volume evolution between the two groups (p < 0.01) with the STABILISE technique; this statistical difference was not found in the TEVAR subgroup. In the HTAD patients, there was a significant difference in the total aortic volume evolution progression between the patients treated with the STABILISE technique and the patients treated with TEVAR (+160.1 ± 52.3% vs. +47 ± 22.5%, p < 0.01 and +189.5 ± 92.5% vs. +58.6 ± 34.8%, p < 0.01 at 1 year and at the end of follow-up, respectively). Conclusions: TEVAR in the HTAD patients seemed to be associated with poorer anatomical outcomes at 1 year. This result was strongly related to the STABILISE technique which should be considered with care in these specific patients. Full article
(This article belongs to the Special Issue Aortic Diseases and Complications: Diagnosis and Treatment)
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Other

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8 pages, 7073 KiB  
Case Report
Late Post-Dissection Dynamic Intermittent Malperfusion of the Aortic Arch in Association with a Rare Heterogenous LOX Gene Variation
by Barbara Leclercq, Julien Bertolino, Alexandre Rossillon, Vlad Gariboldi, Sarah El Harake, François Silhol, Michel Bartoli, Bernard Vaisse, Axel Bartoli and Gabrielle Sarlon-Bartoli
J. Clin. Med. 2024, 13(4), 952; https://doi.org/10.3390/jcm13040952 - 7 Feb 2024
Viewed by 905
Abstract
Late ischaemic consequences of type A aortic dissection are rare. We present a 6-year late complication of type A aortic dissection treated by Bentall surgery in a 41-year-old patient. The patient presented with several episodes of lipothymia associated with hypertensive attacks with anisotension, [...] Read more.
Late ischaemic consequences of type A aortic dissection are rare. We present a 6-year late complication of type A aortic dissection treated by Bentall surgery in a 41-year-old patient. The patient presented with several episodes of lipothymia associated with hypertensive attacks with anisotension, cervicalgia, hemicranial headache, abdominal pain and lower limb slipping initially on exertion and later at rest. On dynamic examination, we diagnosed an intermittent dynamic occlusion of the aortic arch and rare LOX gene variation, which is considered to be associated with aneurysm or dissection of the ascending aorta in young patients. Surgical treatment by replacement of the ascending aorta and the aortic arch with reimplantation of the brachiocephalic trunk (BcTr) allowed the symptoms to resolve. Full article
(This article belongs to the Special Issue Aortic Diseases and Complications: Diagnosis and Treatment)
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