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JCM
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Surgical Insights into Foot and Ankle Diseases
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Surgical Insights into Foot and Ankle Diseases

A special issue of Journal of Clinical Medicine (ISSN 2077-0383). This special issue belongs to the section "Orthopedics".

Deadline for manuscript submissions: 30 April 2026 | Viewed by 1108

Special Issue Editor

Dr. Konstantinos Tsikopoulos

E-Mail Website
Guest Editor
Orthopedic Department, North Bristol NHS Trust, Bristol BS10 5NB, UK
Interests: lower limb surgery; infection research; foot and ankle
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

The progress of foot and ankle surgery over the last decades has been remarkable. New implants and various new procedures have been introduced in the current clinical practise with a view to optimise clinical outcomes. Indications for surgical intervention have also changed, and joint replacement surgery is gaining popularity. In this Special Issue, we encourage authors to submit papers and share their perspectives related to foot and ankle surgery. Of note, all study designs are welcome except case series and case reports.

Dr. Konstantinos Tsikopoulos
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 250 words) can be sent to the Editorial Office for assessment.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Journal of Clinical Medicine is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • lower limb surgery
  • infection research
  • foot and ankle

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Published Papers (1 paper)

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17 pages, 1685 KB  
Systematic Review
Hybrid Fixation for Syndesmotic Stabilisation: A Systematic Review of Clinical and Biomechanical Evidence
by Jed Bailey, Richard Huynh, Konstantinos Tsikopoulos, Lyndon Mason and Vasileios Lampridis
J. Clin. Med. 2026, 15(1), 107; https://doi.org/10.3390/jcm15010107 - 23 Dec 2025
Viewed by 823
Abstract
Background: Syndesmotic injuries are a common type of ankle trauma, occurring in isolation or with fracture. Hybrid fixation (HF) combines screw and dynamic fixation, either as separate implants or within an integrated device, to stabilise such injuries. Despite clinical interest, no comprehensive evidence [...] Read more.
Background: Syndesmotic injuries are a common type of ankle trauma, occurring in isolation or with fracture. Hybrid fixation (HF) combines screw and dynamic fixation, either as separate implants or within an integrated device, to stabilise such injuries. Despite clinical interest, no comprehensive evidence synthesis exists. This review evaluates clinical and biomechanical evidence on HF for syndesmotic stabilisation. Methods: EMBASE, Medline, the Cochrane Library, and PubMed databases were systematically searched until May 2025 to identify studies reporting HF in adults with syndesmotic injury. Clinical studies were appraised using the Methodological Index for Non-Randomised Studies (MINORS) and biomechanical studies using the Quality Appraisal for Cadaveric Studies (QUACS) tool. Given variation in HF configuration and outcome reporting, qualitative synthesis was performed in accordance with PRISMA 2020 guidelines. Results: Six studies were included: four clinical and two biomechanical. Across clinical studies, 93 patients received HF. Mean American Orthopaedic Foot and Ankle Society (AOFAS) scores, reported in two studies, were 93.3 at final follow-up. Radiographic outcomes indicated maintained syndesmotic reduction. Malreduction occurred in 3 patients (3.2%), unplanned implant removal in 3 patients (3.2%), and implant failure in 14 patients (15.1%). All implant failures were asymptomatic and confined to one study. Biomechanical studies demonstrated that HF restored native joint kinematics under simulated loading. Conclusions: Current evidence supports HF as an appropriate syndesmotic fixation strategy. However, methodological limitations of the available evidence, including observational design and variable follow-up durations, should be considered. Heterogeneity in construct design, inconsistent outcome reporting, and limited comparative research complicate interpretation. Future research should prioritise standardised outcome reporting and longer follow-up to thoroughly evaluate HF. Full article
(This article belongs to the Special Issue Surgical Insights into Foot and Ankle Diseases)
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