New Advances in Neuroimmunology
A special issue of Journal of Clinical Medicine (ISSN 2077-0383). This special issue belongs to the section "Clinical Neurology".
Deadline for manuscript submissions: closed (22 March 2024) | Viewed by 2586
Special Issue Editors
2. Department of Neurology and Pain Treatment, Immanuel Klinik Rüdersdorf, University Hospital of the Brandenburg Medical School Theodor Fontane, 15562 Rüdersdorf bei Berlin, Germany
3. Faculty of Health Sciences Brandenburg, Brandenburg Medical School Theodor Fontane, 16816 Rüdersdorf bei Berlin, Germany
Interests: neuromuscular disorders; muscle inflammation; myositis; peripheral nerve disorders; skeletal muscle; myopathy; neuromuscular junction; neuroimmunology; autoimmune-inflammatory diseases of the peripheral nervous system; co-stimulation, cytotoxocity, aging; protein homeostasis; protein accumulation
2. Faculty of Health Sciences Brandenburg, Brandenburg Medical School Theodor Fontane, 16816 Rüdersdorf bei Berlin, Germany
3. Department of Neurology and Stroke, University Hospital of Tübingen, 72076 Tübingen, Germany
Interests: multiple sclerosis; CNS immunology; B-cells; neuromyelitis optica spectrum disorder (NMOSD); MOG associated disorders (MOGAD); auto-immune inflammatory disorders of the brain
Special Issue Information
Dear Colleagues,
In recent years, various areas within the vibrant field of Neuroimmunology have substantially advanced. We have learnt of several key events that drive the disease pathology in central demyelinating disorders such as multiple sclerosis as well as in the peripheral nervous system such as in CIDP. These mechanisms include, but are not limited to, mitochondrial cell stress, cell signaling, immuno-regulation by cytokines, chemokines and co-stimulation, and many others. Most importantly, we begin to better understand the complex underlying interrelationships between inflammation, protein metabolism, cell death, and regeneration in the brain, peripheral nerves, and skeletal muscle.
In light of a growing understanding of the disease pathology in neuroimmunologic and neuroinflammatory disorders, successful clinical trials have recently paved the way for new drug approvals by the FDA and EMA, e.g., for satralizumab, inebilizumab, efgartigimod, and others.
The main aim of this Special Collection is to provide an overarching insight into the recent advances in Neuroimmunology with a particular focus on pathomechanisms and interactions between the nervous system, glial cells, immune cells, and mediators such as cytokines and chemokines as well as how to design effective treatment strategies.
We warmly welcome your valuable manuscripts with relevance to any aspect of central or peripheral Neuroimmunology. We very much look forward to receiving your original research and reviews with novel clinical or mechanistic insight.
Prof. Dr. Jens Schmidt
Dr. Markus Krumbholz
Guest Editors
Manuscript Submission Information
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Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Journal of Clinical Medicine is an international peer-reviewed open access semimonthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
Keywords
- auto-immune inflammatory diseases of the central and peripheral nervous system
- multiple sclerosis
- NMOSD
- auto-immune encephalitis, myositis, neuritis
- GBS, CIDP
- myasthenia gravis, LEMS
- treatment response, assessment, and design of novel therapeutics
- pathomechanisms and model systems with direct clinical, experimental, or translational relevance in neuroim-munology and neuroinflammation including, but not limited to:
- pro-inflammatory cell stress
- co-stimulation
- auto-antibodies
- aging
- mitochondrial cell stress,
- protein metababolism including proteasome, autophagy, necroptosis, etc.
- cell signaling, signal transduction, cytokines, chemokines, epigenetic regulation
