Challenges in Fertility Preservation
A special issue of Journal of Clinical Medicine (ISSN 2077-0383). This special issue belongs to the section "Reproductive Medicine & Andrology".
Deadline for manuscript submissions: 30 May 2025 | Viewed by 76
Special Issue Editors
Interests: cervical cancer prevention; gynaecological surgery; endometriosis; laparoscopic surgery; reproductive medicine; fertility preservation; cryopreservation
Special Issue Information
Dear Colleagues,
Survival rates after cancer treatment have increased due to advances in oncology. However, oncological treatments such as surgery, chemotherapy, and radiotherapy can be gonadotoxic and can reduce fertility. Ovarian reserves can be damaged by oncological treatments, resulting in drastic reduction in fertility. For this reason, women diagnosed with cancer should be referred to IVF centers before starting gonadotropic therapies, since having children is an important factor in the quality of life overall.
The gold standard technique in fertility preservation is oocyte and/or embryo cryopreservation, depending on the age of the patient, the woman’s desire, the presence of a partner, and the law of the country in question. The experimental label for cryopreservation and ovarian tissue auto-transplantation in fertility preservation was removed in December 2019 by the American Society of Reproductive Medicine. This procedure is the only feasible fertility preservation technique in prepubertal girls and in women who cannot delay the start of oncological treatments. Research on this procedure has come to concern issues involving increasing the longevity of transplanted tissue and avoiding the potential risk of neoplastic cell reintroduction. In particular, studies are presently focused on research into ovarian stem cells, in vitro ovarian follicle growth, and artificial ovaries.
The aim of this Special Issue of the Journal of Clinical Medicine is to report the latest research on oncofertility and fertility preservation techniques. We aim to attract original research articles and reviews on the latest updates in oncofertility and fertility preservation, with the larger aim of improving clinical outcomes and ensuring optimal short- and long-term management.
Dr. Loris Marin
Prof. Dr. Guido Ambrosini
Guest Editors
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Keywords
- fertility preservation
- oocytes cryopreservation
- embryo cryopreservation
- ovarian tissue transplantation
- gonadotoxic therapy
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