Clinical Challenges in Renal Transplant Rejection
A special issue of Journal of Clinical Medicine (ISSN 2077-0383). This special issue belongs to the section "Nephrology & Urology".
Deadline for manuscript submissions: closed (20 March 2024) | Viewed by 1165
Special Issue Editor
Special Issue Information
Dear Colleagues,
Although great advances in renal transplant surgery have been made, rejection among transplant recipients remains a major health issue. When transplanting tissue or cells from a donor that are genetically different from those of the recipient, an immune response will be triggered against the transplanted graft. The introduction of immunosuppressants has allowed transplanted kidneys to survive for a longer period of time, but episodes of rejection still occur, leading to graft loss. Several factors have been identified to increase the risk of rejection, but the mechanisms triggering the immune response are still poorly understood. The Special Issue examines the challenges posed by chronic rejection, a long-term process that can ultimately lead to graft failure. Furthermore, we hope to highlight the current understanding of the mechanisms underlying transplant rejection, as well as novel diagnostic and therapeutic strategies being employed to address this clinical challenge. This Issue emphasizes the need for early detection and intervention to prevent or slow down the progression of chronic rejection.
In this Special Issue of the Journal of Clinical Medicine, we welcome original articles and reviews that explore different aspects of the rejection of kidney allografts. Since there are many challenges to achieving successful outcomes for renal transplants, we hope to help physicians and researchers deal with them.
Prof. Dr. Grzegorz Piecha
Guest Editor
Manuscript Submission Information
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Keywords
- renal transplant
- kidney transplantation
- renal allograft
- acute rejection
- chronic rejection
- kidney transplant rejection prevention
