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New Insights in Ophthalmic Surgery
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New Insights in Ophthalmic Surgery

A special issue of Journal of Clinical Medicine (ISSN 2077-0383). This special issue belongs to the section "Ophthalmology".

Deadline for manuscript submissions: 20 June 2025 | Viewed by 2159

Special Issue Editor

Prof. Dr. Irina S. Barequet

E-Mail Website
Guest Editor
Goldschleger Eye Institute, Sheba Medical Center, Faculty of Medical & Health Sciences, Tel Aviv University, Tel Hashomer, Israel
Interests: ophthalmology; cataract surgery; corneal surgery; refractive surgery; anterior segment

Special Issue Information

Dear Colleagues,

Ophthalmic surgery has evolved continuously in the past decade. Thus, novel technologies and new surgical techniques enable the more efficient rehabilitation and preservation of vision and the eye. An expansion of indications for surgeries and technologies that better assess the primary condition and the follow-up open new avenues for patients. Accordingly, many new horizons are opening, allowing the promotion and rehabilitation of vision function, along with improvements in the quality of life of these patients.

Accordingly, a Special Issue called “New Insights in Ophthalmic Surgery” is announced. This Special Issue is calling for original research and reviews that have investigated new surgical methods of ophthalmic surgery, novel techniques, outcomes and safety, modifications and improvements of previously used procedures, and decision-making guidelines.

Prof. Dr. Irina S. Barequet
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Journal of Clinical Medicine is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • cataract surgery
  • corneal surgery
  • refractive surgery
  • ocular surface reconstruction, anterior segment surgery

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Further information on MDPI's Special Issue policies can be found here.

Published Papers (4 papers)

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Research

Jump to: Review, Other

8 pages, 197 KiB  
Article
Descemet Stripping Only for Symptomatic Fuchs Endothelial Dystrophy—A Retrospective Case Series Comparing ROCK-I vs. Hypertonic Sodium Chloride for Post-Surgical Adjuvant Therapy
by Eyal Cohen, Nizar Din, Sultan Aldrees, Michael Mimouni, Tanya Trinh, Nir Sorkin, Larissa Gouvea, Clara C. Chan and Allan R. Slomovic
J. Clin. Med. 2025, 14(5), 1512; https://doi.org/10.3390/jcm14051512 - 24 Feb 2025
Viewed by 407
Abstract
Purpose: To report our experience with Descemet stripping only (DSO) for the treatment of Fuchs endothelial corneal dystrophy. Methods: Thirteen eyes of 9 patients with symptomatic Fuchs endothelial dystrophy underwent a 4 mm central Descemetorhexis without graft implantation between June 2017 and [...] Read more.
Purpose: To report our experience with Descemet stripping only (DSO) for the treatment of Fuchs endothelial corneal dystrophy. Methods: Thirteen eyes of 9 patients with symptomatic Fuchs endothelial dystrophy underwent a 4 mm central Descemetorhexis without graft implantation between June 2017 and July 2020. All patients had central confluent guttata, undetectable central endothelial cell count by specular microscopy, and healthy peripheral corneal endothelium. In 6 eyes, the procedure was combined with phacoemulsification and intraocular lens implantation. Eight eyes were treated with topical rho-associated protein kinase (Rock) inhibitors and five eyes were treated with hypertonic sodium chloride 5%, post operatively. Results: All eyes completed at least 4 months of post-operative follow-up (mean follow-up 12.0 ± 7.9 mo; 4–29 mo). Mean patient age was 70 ± 6 years. All eyes achieved corneal clearance with an average time for clearance of 7.2 ± 2.4 weeks. Mean endothelial cell count postoperatively was 778 ± 228. Mean central corneal thicknesses pre- and postoperatively were 620 ± 100 and 560 ± 58 μm, respectively. Eleven eyes achieved improvement in visual acuity and in two eyes vision remained unchanged, with mean visual acuity 0.392 to 0.225 logMAR; p = 0.001. Also, all patients reported subjective improvement in the quality of vision. ROCK inhibitors compared to hypertonic sodium chloride 5% did not show statistically significant differences in time for corneal clearance or endothelial cell counts postoperatively but did show a trend towards faster corneal clearance and higher endothelial cell counts postoperatively among the ROCK inhibitors-treated eyes. Conclusions: In patients with Fuchs endothelial dystrophy and visual degradation secondary to central guttata, DSO represents a viable procedure for visual rehabilitation. Full article
(This article belongs to the Special Issue New Insights in Ophthalmic Surgery)
8 pages, 191 KiB  
Article
Combined Penetrating Keratoplasty and Vitrectomy: Long-Term Follow-Up Results
by Orit Vidne-Hay, Amir Alhalel and Irina S. Barequet
J. Clin. Med. 2024, 13(23), 7468; https://doi.org/10.3390/jcm13237468 - 8 Dec 2024
Viewed by 656
Abstract
Purpose: To assess the long-term outcomes of combined penetrating keratoplasty (PKP) and pars plana vitrectomy (PPV). Methods: A retrospective review of eyes that underwent combined surgery followed for 12 months or longer. Demographic data, indications for surgery, and pre-/post-surgical eye examinations [...] Read more.
Purpose: To assess the long-term outcomes of combined penetrating keratoplasty (PKP) and pars plana vitrectomy (PPV). Methods: A retrospective review of eyes that underwent combined surgery followed for 12 months or longer. Demographic data, indications for surgery, and pre-/post-surgical eye examinations were retrieved. Results: Thirteen consecutive eyes (13 patients) were enrolled. The mean age was 51.5 ± 20.5 years, and the mean follow-up time was 67 ± 36.9 months. All cases had severe corneal opacity. Indications for surgery included retinal detachment (76.9%), dropped lens (7.7%), dropped intraocular lens (7.7%), and endophthalmitis with corneal abscess (7.7%). Visual acuity improved in 46.1% of the cases, though in most cases visual acuity remained low, and decreased in 23% of the cases. In 23% of the cases (3 eyes), ambulatory vision was achieved for more than 12 months and in 15.4% for three years. Silicone oil tamponade was used in all cases of retinal detachment (10 eyes). Of these eyes, at the final follow-up, four eyes were attached, two eyes were partially attached, and corneal opacity prevented retinal visualization in three eyes. One eye was eviscerated and one eye developed phthisis. Postoperatively, 61.5% of the cases underwent repeated PKP for graft decompensation. At the final visit, graft failure was observed in 75% of the cases. Conclusions: The long-term follow-up of eyes that underwent combined PKP and PPV supports this technique in complex cases for eye and vision preservation. The main problem after combined surgery is the long-term survival of the corneal graft which may require repeated PKP surgeries. With this approach, in 23% of the cases, ambulatory vision was maintained for more than 12 months. Full article
(This article belongs to the Special Issue New Insights in Ophthalmic Surgery)

Review

Jump to: Research, Other

11 pages, 826 KiB  
Review
Mushroom Penetrating Keratoplasty: A Narrative Review
by Pietro Bergamaschi, Linda Marie Louise Busin, Angeli Christy Yu and Massimo Busin
J. Clin. Med. 2025, 14(7), 2351; https://doi.org/10.3390/jcm14072351 - 29 Mar 2025
Viewed by 156
Abstract
While full-thickness penetrating keratoplasty (PK) has seen a decline in favor of partial-thickness techniques like endothelial keratoplasty (EK) and anterior lamellar keratoplasty (ALK), PK remains indicated for corneal disease involving the entire corneal thickness. Mushroom keratoplasty (MK) is a noteworthy modification of PK, [...] Read more.
While full-thickness penetrating keratoplasty (PK) has seen a decline in favor of partial-thickness techniques like endothelial keratoplasty (EK) and anterior lamellar keratoplasty (ALK), PK remains indicated for corneal disease involving the entire corneal thickness. Mushroom keratoplasty (MK) is a noteworthy modification of PK, designed to combine the refractive benefits of a large-diameter anterior lamellar graft with the graft survival advantage of limited replacement of the corneal endothelium. Leveraging the use of a microkeratome, the MK donor graft can be prepared by microkeratome dissection, thereby achieving a central interface compatible with 20/20 Snellen vision. This review explores the various surgical techniques, visual outcomes, graft survival rates, and complication rates associated with MK for various indications. Full article
(This article belongs to the Special Issue New Insights in Ophthalmic Surgery)
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Other

Jump to: Research, Review

10 pages, 1886 KiB  
Case Report
Novel Surgical Approach for Aphakia and Iridodialysis: Artificial Iris and Scleral-Fixated Lens as a Single Complex
by Guglielmo Parisi, Agostino Salvatore Vaiano, Claudio Foti, Francesco Gelormini, Federico Ricardi, Fabio Conte, Maria Marenco, Paola Marolo, Enrico Borrelli and Michele Reibaldi
J. Clin. Med. 2025, 14(5), 1599; https://doi.org/10.3390/jcm14051599 - 27 Feb 2025
Viewed by 478
Abstract
Background: Artificial iris (AI) implantation is an innovative and increasingly utilized surgical procedure for injured eyes with iris trauma. Methods: A 76-year-old female and a 34-year-old male presented at the emergency department with a traumatic corneo-scleral laceration and perforated corneal ulcer, respectively. [...] Read more.
Background: Artificial iris (AI) implantation is an innovative and increasingly utilized surgical procedure for injured eyes with iris trauma. Methods: A 76-year-old female and a 34-year-old male presented at the emergency department with a traumatic corneo-scleral laceration and perforated corneal ulcer, respectively. Emergency surgeries were performed to restore ocular integrity. In both cases, a modified surgical technique involving the implantation of an AI was performed; however, two different models of AI were used. Results: The AIs were sutured with four stitches directly to the scleral-fixated (SF) intra ocular lens (IOL), and the AI-IOL complexes were implanted, as a single unit, and fixated to the sclera using the lens haptics. Before and after the surgery, patients underwent a comprehensive eye examination, including a visual acuity test. The AI-SF IOL complexes remained well positioned, with no intraocular or extraocular complications observed during the follow-up evaluations of both patients. Conclusions: We reported a straightforward and repeatable modified surgical technique for two patients with two models of AI, both sutured to the SF IOL and fixated to the sclera, as a single unit. This approach may serve as an excellent alternative for managing aphakic eyes with extensive iridodialysis or partial aniridia. Full article
(This article belongs to the Special Issue New Insights in Ophthalmic Surgery)
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