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Advances in the Diagnosis, Treatment, and Prognosis of Hearing Loss
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Advances in the Diagnosis, Treatment, and Prognosis of Hearing Loss

A special issue of Journal of Clinical Medicine (ISSN 2077-0383). This special issue belongs to the section "Otolaryngology".

Deadline for manuscript submissions: closed (1 May 2024) | Viewed by 6825

Special Issue Editors

Prof. Dr. Lone Percy-Smith

E-Mail Website
Guest Editor
Center for Hearing and Balance, Rigshospitalet, 2100 Copenhagen, Denmark
Interests: hearing loss for children and adolescents; playful learning; serious gaming for use in audiology
Prof. Dr. Per Caye-Thomasen

E-Mail Website
Guest Editor
Copenhagen Hearing and Balance Center, Ear, Nose and Throat (ENT) and Audiology Clinic, Rigshospitalet, Copenhagen University Hospital, Copenhagen, Denmark
Interests: hearing rehabilitation; cochlear implantation; outcome studies
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

Hearing loss (HL) is an increasing concern in modern society. The introduction of universal hearing screening, early diagnosis of HL, early intervention with hearing technology (hearing aids (HA), cochlear implants (CI)), and clinical treatments combined with specific educational intervention have markedly changed the lives of children and adults with HL. New generations with HL are emerging, and it has been documented that medical–surgical, technical, and educational interventions have allowed people with HL to achieve outcomes of audition and language never before documented for those with severe HL. It is, however,  important to recognize that even though HL is treated with state-of-the-art hearing technology, people with HL do not have normal hearing (NH). Distance to the sound signal and background noise are still challenging for any person with HL. Therefore, it is of utmost importance to bring together updated knowledge on the emerging new generations with a specific focus on how challenges are solved around the globe.

Aim and scope of this Special Issue:

This Special Issue aims to provide information on studies that focus on the diagnosis, screening, nonsurgical interventions, clinical treatments, and prognosis of HL.

Prof. Dr. Lone Percy-Smith
Prof. Dr. Per Caye-Thomasen
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Journal of Clinical Medicine is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • hearing loss
  • hearing aids
  • cochlear implants
  • nonsurgical interventions
  • quality of life

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Published Papers (6 papers)

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Research

15 pages, 3679 KiB  
Article
Hearing Screening for Congenital CytoMegaloVirus—Exploring Parents’ Experiences of Completing Targeted Congenital Cytomegalovirus Screening at the Time of Their Infants’ Newborn Hearing Screening
by Emma Webb, Jan Hodgson, Alanna N. Gillespie, Cheryl A. Jones, Zeffie Poulakis, Janis Wong and Valerie Sung
J. Clin. Med. 2024, 13(15), 4367; https://doi.org/10.3390/jcm13154367 - 26 Jul 2024
Viewed by 1011
Abstract
Background/Objectives: Congenital cytomegalovirus (cCMV) is the leading infectious cause of sensorineural hearing loss and neurodevelopmental disabilities, with prompt detection (<21 days of life) required to enable accurate diagnosis and anti-viral treatment where clinically appropriate. International guidelines recommend cCMV screening for infants who do [...] Read more.
Background/Objectives: Congenital cytomegalovirus (cCMV) is the leading infectious cause of sensorineural hearing loss and neurodevelopmental disabilities, with prompt detection (<21 days of life) required to enable accurate diagnosis and anti-viral treatment where clinically appropriate. International guidelines recommend cCMV screening for infants who do not pass their Universal Newborn Hearing Screening (UNHS). This study aimed to explore parental experiences of targeted cCMV screening through the UNHS in Victoria, Australia between 2019 and 2020 (HearS-cCMV study). Methods: A qualitative study comprising 18 semi-structured interviews with parents who took saliva swabs from their infants who did not pass their UNHS. A maximum variation sampling strategy was used with data analysed using thematic analysis. Results: Four themes described 18 parents’ experiences of cCMV screening: (1) parents’ lack of CMV awareness prior to cCMV screening; (2) overall positive experience; (3) varied understanding of CMV post screening; and (4) parents were glad to screen their infant for cCMV. Enablers of targeted cCMV screening included the swab being simple and non-invasive, being easier to complete in the hospital than at home, and the screening being well delivered by the staff. Barriers included a potential increase in anxiety, especially with false positives, and the timing of cCMV screening coinciding with their infant not passing UNHS being difficult for some parents. Conclusions: Parent experiences of targeted cCMV screening were positive. Increasing public knowledge of cCMV and training staff members to complete the CMV swab would reduce the risk of false positives and associated parental anxiety. This would facilitate successful routine targeted cCMV screening. Full article
(This article belongs to the Special Issue Advances in the Diagnosis, Treatment, and Prognosis of Hearing Loss)
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18 pages, 3363 KiB  
Article
A Concert-Based Study on Melodic Contour Identification among Varied Hearing Profiles—A Preliminary Report
by Razvan Paisa, Jesper Andersen, Francesco Ganis, Lone M. Percy-Smith and Stefania Serafin
J. Clin. Med. 2024, 13(11), 3142; https://doi.org/10.3390/jcm13113142 - 27 May 2024
Viewed by 641
Abstract
Background: This study investigated how different hearing profiles influenced melodic contour identification (MCI) in a real-world concert setting with a live band including drums, bass, and a lead instrument. We aimed to determine the impact of various auditory assistive technologies on music [...] Read more.
Background: This study investigated how different hearing profiles influenced melodic contour identification (MCI) in a real-world concert setting with a live band including drums, bass, and a lead instrument. We aimed to determine the impact of various auditory assistive technologies on music perception in an ecologically valid environment. Methods: The study involved 43 participants with varying hearing capabilities: normal hearing, bilateral hearing aids, bimodal hearing, single-sided cochlear implants, and bilateral cochlear implants. Participants were exposed to melodies played on a piano or accordion, with and without an electric bass as a masker, accompanied by a basic drum rhythm. Bayesian logistic mixed-effects models were utilized to analyze the data. Results: The introduction of an electric bass as a masker did not significantly affect MCI performance for any hearing group when melodies were played on the piano, contrary to its effect on accordion melodies and previous studies. Greater challenges were observed with accordion melodies, especially when accompanied by an electric bass. Conclusions: MCI performance among hearing aid users was comparable to other hearing-impaired profiles, challenging the hypothesis that they would outperform cochlear implant users. A cohort of short melodies inspired by Western music styles was developed for future contour identification tasks. Full article
(This article belongs to the Special Issue Advances in the Diagnosis, Treatment, and Prognosis of Hearing Loss)
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13 pages, 1369 KiB  
Article
Piezoelectric Bone Conduction Hearing Implant: A Case Series of Audiological, Surgical and Patient-Reported Outcomes
by Mai Vagle, Michael Bille and Ramon Gordon Jensen
J. Clin. Med. 2024, 13(11), 3111; https://doi.org/10.3390/jcm13113111 - 26 May 2024
Viewed by 1051
Abstract
Objective: To examine the surgical, audiological and patient-reported outcomes of the Osia 2 implant. Methods: Data from 14 consecutive subjects undergoing implantation between April 2022 and November 2023 were reviewed. Ten subjects had conductive hearing loss, three had mixed hearing loss [...] Read more.
Objective: To examine the surgical, audiological and patient-reported outcomes of the Osia 2 implant. Methods: Data from 14 consecutive subjects undergoing implantation between April 2022 and November 2023 were reviewed. Ten subjects had conductive hearing loss, three had mixed hearing loss and one had single-sided deafness (SSD). Warble tone thresholds, Pure Tone Average (PTA4) and Speech Discrimination Score (SDS) in quiet and in noise were determined unaided and aided. The subjective outcome was determined from two standardized questionnaires: (1) International Outcome Inventory for Hearing Aids (IOI-HA) and (2) Speech, Spatial and Qualities of Hearing Scale 12 (SSQ12b). Results: Unexpected postoperative pain was found in four cases. The warble tone thresholds exhibited a consistent reduction across all frequencies, contributing to a mean decrease of 27 dB in the aided PTA4. SDS demonstrated notable improvements, with a 57.3% increase at 50 dB and a 55.6% increase at 65 dB. In noise, SDS exhibited a 43.9% improvement. The mean IOI-HA Score was 3.8, and the mean overall score for SSQ12b was 6.6, with consistent findings across the subgroups. Conclusions: The Osia device emerges as a promising recommendation for individuals with conductive or mixed hearing loss, possibly also for those with SSD. Its safety and efficacy profile aligns with the broader category of active transcutaneous devices, demonstrating a reduced risk of wound infection compared to percutaneous alternatives. Both audiological assessments and subjective evaluations revealed positive outcomes. Full article
(This article belongs to the Special Issue Advances in the Diagnosis, Treatment, and Prognosis of Hearing Loss)
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13 pages, 822 KiB  
Article
The Effect of LENA (Language ENvironment Analysis) for Children with Hearing Loss in Denmark including a Pilot Validation for the Danish Language
by Jane Lignel Josvassen, Victoria Amalie Michael Hedegaard, Mie Lærkegård Jørgensen and Lone Percy-Smith
J. Clin. Med. 2024, 13(9), 2688; https://doi.org/10.3390/jcm13092688 - 3 May 2024
Viewed by 1353
Abstract
Background/Objectives: This study aimed to investigate whether day-long recordings with Language Environment Analysis (LENA) can be utilized in a hospital-based Auditory Verbal Therapy (AVT) program in Denmark for children with hearing loss and to conduct a pilot validation in the Danish language. Methods [...] Read more.
Background/Objectives: This study aimed to investigate whether day-long recordings with Language Environment Analysis (LENA) can be utilized in a hospital-based Auditory Verbal Therapy (AVT) program in Denmark for children with hearing loss and to conduct a pilot validation in the Danish language. Methods and materials: A license for the LENA system (LENA SP) was purchased, and trials were offered to three families enrolled in the AVT program. Each family made two day-long recordings with 3–4 months in between and received feedback during the therapy sessions. From 18 × 10-min clips randomly pulled out of the recordings, a comparison of adult word counts (AWC) between the LENA algorithm counts and the counts made by two human transcribers was made and used for the pilot validation. Results: LENA proved to be valuable as a guiding tool for Danish parents. Pilot validation showed good correlations and an acceptable limit of agreement (LoA). Conclusions: LENA holds the potential for Danish validation and use in AVT/clinical practice. When used in clinical practice, parents must be informed of the biases and limitations, and possible ethical issues must be considered. Because of the GDPR rules, there is a need to discuss the possibility of implementing this tool clinically in Denmark and the EU. Full article
(This article belongs to the Special Issue Advances in the Diagnosis, Treatment, and Prognosis of Hearing Loss)
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14 pages, 3633 KiB  
Article
Hearing Recovery Prediction for Patients with Chronic Otitis Media Who Underwent Canal-Wall-Down Mastoidectomy
by Minsu Chae, Heesoo Yoon, Hwamin Lee and June Choi
J. Clin. Med. 2024, 13(6), 1557; https://doi.org/10.3390/jcm13061557 - 8 Mar 2024
Viewed by 995
Abstract
Background: Chronic otitis media affects approximately 2% of the global population, causing significant hearing loss and diminishing the quality of life. However, there is a lack of studies focusing on outcome prediction for otitis media patients undergoing canal-wall-down mastoidectomy. Methods: This study proposes [...] Read more.
Background: Chronic otitis media affects approximately 2% of the global population, causing significant hearing loss and diminishing the quality of life. However, there is a lack of studies focusing on outcome prediction for otitis media patients undergoing canal-wall-down mastoidectomy. Methods: This study proposes a recovery prediction model for chronic otitis media patients undergoing canal-wall-down mastoidectomy, utilizing data from 298 patients treated at Korea University Ansan Hospital between March 2007 and August 2020. Various machine learning techniques, including logistic regression, decision tree, random forest, support vector machine (SVM), extreme gradient boosting (XGBoost), and light gradient boosting machine (light GBM), were employed. Results: The light GBM model achieved a predictive value (PPV) of 0.6945, the decision tree algorithm showed a sensitivity of 0.7574 and an F1 score of 0.6751, and the light GBM algorithm demonstrated the highest AUC-ROC values of 0.7749 for each model. XGBoost had the most efficient PR-AUC curve, with a value of 0.7196. Conclusions: This study presents the first predictive model for chronic otitis media patients undergoing canal-wall-down mastoidectomy. The findings underscore the potential of machine learning techniques in predicting hearing recovery outcomes in this population, offering valuable insights for personalized treatment strategies and improving patient care. Full article
(This article belongs to the Special Issue Advances in the Diagnosis, Treatment, and Prognosis of Hearing Loss)
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11 pages, 2281 KiB  
Article
Factors Predicting Subjective Satisfaction for Successful Hearing Aid Adaptation
by Jeong Hun Jang, Jungho Ha, Oak-Sung Choo, Young Sook Kang, Hun Yi Park and Yun-Hoon Choung
J. Clin. Med. 2024, 13(2), 398; https://doi.org/10.3390/jcm13020398 - 11 Jan 2024
Viewed by 1153
Abstract
(1) Background: For successful hearing aid (HA) use during daily life, an objective parameter reflecting the subjective satisfaction is required. We explored the aided hearing status, hearing in noise test (HINT) scores, and subjective outcomes to predict performance improvements in everyday living. (2) [...] Read more.
(1) Background: For successful hearing aid (HA) use during daily life, an objective parameter reflecting the subjective satisfaction is required. We explored the aided hearing status, hearing in noise test (HINT) scores, and subjective outcomes to predict performance improvements in everyday living. (2) Methods: A total of 406 patients with hearing loss (HL) who were prescribed HAs were included and were divided into two groups according to the symmetricity of HL. The relationship between audiometric data and subjective questionnaires under unaided and aided (3 months) conditions were investigated. (3) Results: Patients with symmetric HL showed a significant HINT signal-to-noise ratio (SNR) change and significant increase in their subjective satisfaction questionnaire score under the bilateral HA condition. On the other hand, the HINT SNR change and subjective questionnaire score showed various significances according to the side of HA (better or worse hearing) in asymmetric HL HINT SNR and was significantly correlated with the subjective questionnaire score in symmetric HL patients and AHL patients with unilateral HA in their better ear. (4) Conclusions: The HINT SNR improvement after long-term HA use could be an effective tool for predicting the subjective satisfaction of HA use and HA validation. Full article
(This article belongs to the Special Issue Advances in the Diagnosis, Treatment, and Prognosis of Hearing Loss)
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