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Further Advances in Electrocardiography, Cardiac Arrhythmias, and Arrhythmogenic Disorders: 2nd Edition

A special issue of Journal of Clinical Medicine (ISSN 2077-0383). This special issue belongs to the section "Cardiology".

Deadline for manuscript submissions: 25 July 2026 | Viewed by 714

Special Issue Editor

Dr. Paweł T. Matusik

E-Mail Website
Guest Editor
Department of Electrocardiology, Institute of Cardiology, Faculty of Medicine, Jagiellonian University Medical College, The John Paul II Hospital, 31-008 Kraków, Poland
Interests: cardiac arrhythmias; arrhythmogenic disorders; atrial fibrillation; cardiac pacing; implantable cardioverter-defibrillators; cardiac resynchronization therapy; catheter ablation
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

Novel electrocardiographic criteria, along with new algorithms for the diagnostics and treatment of arrhythmias, have been proposed, enabling more personalized patient management, including the more rational use of imaging, implantable cardioverter defibrillators, cardiac resynchronization therapy, and catheter ablation. Progress has additionally been made in the diagnostics, treatment, and classification of arrhythmogenic disorders. Moreover, advancements in imaging and cardiovascular genetics have improved diagnostics and risk stratification; however, personalized paths in arrhythmia management are increasingly needed.

This Special Issue of the Journal of Clinical Medicine, “Further Advances in Electrocardiography, Cardiac Arrhythmias, and Arrhythmogenic Disorders: 2nd Edition”, focuses on recent improvements, developments, and findings regarding the diagnostics and treatment of cardiac arrhythmias and arrhythmogenic disorders, including channelopathies and cardiomyopathies. We seek papers that summarize the current state of knowledge, investigate arrhythmias related to specific diseases (e.g., sleep apnea) or disciplines, and highlight potential gaps in our understanding of cardiac arrhythmias.

We would like to invite you to contribute to the second edition of this Special Issue; in the first volume, we published 5 papers. For more details, please visit the following link: https://www.mdpi.com/journal/jcm/special_issues/cardiac_arrhythmias_research.

Dr. Paweł T. Matusik
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 250 words) can be sent to the Editorial Office for assessment.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Journal of Clinical Medicine is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • electrocardiography
  • cardiac arrhythmias
  • genetics
  • cardiac pacing
  • implantable cardioverter defibrillators
  • cardiac resynchronization therapy
  • magnetic resonance imaging
  • catheter ablation
  • arrhythmogenic disorders
  • channelopathy
  • cardiomyopathy

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Research

13 pages, 826 KB  
Article
Exploring Sex and Clinical Factors Associated with Long-Term Survival After Implantable Cardioverter-Defibrillator Implantation: A 10-Year Cohort Study
by Rebeca Lorca, María Salgado, Cristina Helguera, Alberto Alen, Francisco González-Urbistondo, Rosana González-Mesa, Paula Bouzón, Daniel García, Rodrigo Di Massa, Rut Álvarez-Velasco, José Manuel Rubín and Pablo Avanzas
J. Clin. Med. 2026, 15(3), 1275; https://doi.org/10.3390/jcm15031275 - 5 Feb 2026
Viewed by 430
Abstract
Background: Sex-related differences in outcomes after implantable cardioverter-defibrillator (ICD) implantation remain incompletely understood. Although women receive ICDs less frequently, whether their long-term survival differs from that of men in real-world clinical practice is not well established. We aimed to evaluate sex-specific mortality [...] Read more.
Background: Sex-related differences in outcomes after implantable cardioverter-defibrillator (ICD) implantation remain incompletely understood. Although women receive ICDs less frequently, whether their long-term survival differs from that of men in real-world clinical practice is not well established. We aimed to evaluate sex-specific mortality and relative survival in a large consecutive cohort of ICD recipients from a tertiary hospital. Methods: We conducted a retrospective cohort study including all consecutive patients who underwent ICD implantation at a tertiary hospital between 2015 and 2025. Demographic features, device indication, and mortality were obtained through clinical records. Relative survival (observed vs. expected) was estimated using the Ederer II method with national life tables. A Cox proportional hazards model assessed the effect of sex on mortality. Results: A total of 1091 patients (82.1% men; mean age 63.1 ± 13.1 years) were included. During a mean follow-up of 4.33 ± 3.22 years, 230 patients died (21.1%). Women showed lower unadjusted all-cause mortality than men: 24 deaths (18.0%) vs. 206 (20.6%). Women had significantly higher left ventricular ejection fraction (41.5 ± 23.6% vs. 37.2 ± 18.1%, p = 0.0046), less ischemic cardiomyopathy, and lower prevalence of cardiovascular risk factors. Although univariable analysis suggested lower mortality in women (HR 0.58, 95% CI 0.38–0.90; p = 0.014), multivariable analysis indicated that sex was not an independent predictor of mortality (HR 0.81, 95% CI 0.53–1.26). Relative survival revealed a substantial long-term mortality burden in ICD carriers, especially in men: men: 4-year survival 82.3% (expected 93.2%); 8-year 66.7% (85.6%); 12-year 56.0% (76.8%); women: 4-year survival 89.1% (expected 96.7%); 8-year 77.1% (92.8%); 12-year 77.1% (89.2%). Conclusions: In this large real-world cohort of ICD recipients, women showed lower unadjusted mortality and a smaller excess mortality compared with the general population. However, sex was not an independent predictor of survival after multivariable adjustment. These findings may indicate that observed survival differences are largely explained by differences in clinical profile and comorbidity burden rather than by sex itself. Full article
(This article belongs to the Special Issue Further Advances in Electrocardiography, Cardiac Arrhythmias, and Arrhythmogenic Disorders: 2nd Edition)
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