Heart Disease Complicated by HIV Infection: Predictors, Diagnosis and Treatment Options
A special issue of Journal of Clinical Medicine (ISSN 2077-0383). This special issue belongs to the section "Cardiology".
Deadline for manuscript submissions: 20 December 2024 | Viewed by 274
Special Issue Editor
Special Issue Information
Dear Colleagues,
Over the last two decades, following the introduction of potent high-genetic barrier regimens in the aging population, HIV medicine has progressively focused on comorbidities and age-related health issues. People living with HIV (PLWH) are disproportionally affected by cardiovascular disease (both in terms of morbidity and mortality) which is not entirely explained by the traditional risk factors, such as age, gender, smoker status, diabetes, family history, hypertension, and weight.
Several studies have addressed the additional role of HIV-related immune activation and inflammation, but many questions remain open. HIV infection is considered an independent predictor of heart disease, meaning it should be managed accordingly, although real-life data report an insufficient level of medical attention and patient compliance.
Heart disease requires multilevel interventions, more aggressive investigations, higher clinician and patient awareness, along with treatment optimization. Antiretrovirals and the potential for drug-to-drug interactions may also complicate this scenario.
More studies are needed in this population to refine the risk prediction tools, identify subclinical diseases, provide recommendations, and standardize management.
The aim of this Special Issue is to focus on the peculiarity of cardiovascular disease in PLWH, addressing the clinical issue in terms of prediction tools, pathogenesis, and treatment options.
Dr. Diego Ripamonti
Guest Editor
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Keywords
- cardiovascular disease
- HIV infection
- HAART
- biomarkers
- coronary artery diseases
- inflammation
- arterial stiffness
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