Search for Articles:
Title / Keyword
Author / Affiliation / Email
Journal
Article Type
 
 
Advanced Search
 
Section
Special Issue
Volume
Issue
Number
Page
 
5.2
2.9
Journals
JCM
Special Issues
Current Trends and Future Challenges in Coronary Artery Disease
jcm-logo
Submit to JCM Review for JCM Propose a Special Issue

Journal Menu

► Journal Menu

Journal Browser

► Journal Browser
share announcement

Current Trends and Future Challenges in Coronary Artery Disease

A special issue of Journal of Clinical Medicine (ISSN 2077-0383). This special issue belongs to the section "Cardiology".

Deadline for manuscript submissions: closed (10 March 2026) | Viewed by 691

Special Issue Editor

Dr. Federica Agnello

E-Mail
Guest Editor
1. Department of Cardiology, Università degli Studi di Enna “Kore”, Enna, Italy
2. Division of Cardiology, Ospedale Umberto I, ASP4 di Enna, Enna, Italy
Interests: atheroslerosis; coronary revascularization; lipid-lowering therapy; antithrombotic therapy

Special Issue Information

Dear Colleagues,

Coronary artery disease is a significant cause of global mortality that imposes a substantial economic burden on healthcare systems. Over last decades, relevant progress in the field of cardiovascular research has led to advancement in diagnosis, prevention, and treatment. New imaging modalities (both invasive and non-invasive), innovative pharmacological agents, development in percutaneous coronary intervention strategies have been introduced, transforming the daily clinical practice.

However, important challenges remain, such as the early identification of high-risk patients, the management of residual risk, the treatment of complex patients and the integration of precision medicine approaches into daily clinical practice.

This Special Issue of the Journal of Clinical Medicine, entitled “Current Trends and Future Challenges in Coronary Artery Disease” aims to provide an updated and comprehensive overview of the latest scientific and clinical trends in cardiological field, as well as to discuss the unresolved questions that will shape future research and practice.

We invite authors to submit original research, comprehensive reviews and meta-analyses.

Dr. Federica Agnello
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 250 words) can be sent to the Editorial Office for assessment.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Journal of Clinical Medicine is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • coronary artery disease
  • cardiovascular prevention
  • coronary computed tomography angiography (CCTA)
  • CT-derived fractional flow reserve (FFR-CT)
  • intracoronary imaging
  • residual risk
  • functional assessment
  • artificial intelligence in cardiology
  • percutaneous coronary intervention

Benefits of Publishing in a Special Issue

  • Ease of navigation: Grouping papers by topic helps scholars navigate broad scope journals more efficiently.
  • Greater discoverability: Special Issues support the reach and impact of scientific research. Articles in Special Issues are more discoverable and cited more frequently.
  • Expansion of research network: Special Issues facilitate connections among authors, fostering scientific collaborations.
  • External promotion: Articles in Special Issues are often promoted through the journal's social media, increasing their visibility.
  • Reprint: MDPI Books provides the opportunity to republish successful Special Issues in book format, both online and in print.

Further information on MDPI's Special Issue policies can be found here.

Published Papers (1 paper)

Order results
Result details
Show export options expand_more Show export options expand_less
Select all
Export citation of selected articles as:

Research

11 pages, 719 KB  
Article
Assessment of Paclitaxel Drug-Coated Balloon-Only Angioplasty for Multivessel Coronary Artery Disease
by Ioannis Merinopoulos, Natasha Corballis, U Bhalraam, Rajkumar Natarajan, Tharusha Gunawardena, Johannes Reinhold, Clint Maart, Chris Sawh, Sreekumar Sulfi, Trevor Wistow, Alisdair Ryding, Tim Gilbert, Vassilios S. Vassiliou and Simon C. Eccleshall
J. Clin. Med. 2026, 15(1), 204; https://doi.org/10.3390/jcm15010204 - 26 Dec 2025
Cited by 1 | Viewed by 469
Abstract
Background: There are limited data about the use of drug-coated balloon (DCB)-only angioplasty for multivessel coronary disease. Objectives: The aim of this study was to assess the safety and efficacy of DCB-only angioplasty as compared with second-generation drug-eluting stents (DESs) in [...] Read more.
Background: There are limited data about the use of drug-coated balloon (DCB)-only angioplasty for multivessel coronary disease. Objectives: The aim of this study was to assess the safety and efficacy of DCB-only angioplasty as compared with second-generation drug-eluting stents (DESs) in patients undergoing multivessel angioplasty. Methods: We compared major adverse cardiovascular events (MACEs) in all patients undergoing multivessel angioplasty in our institution from 1 January 2015 until 15 November 2019, with either the DCB-only or DES-only strategy. The primary endpoint of our study was a MACE, including cardiovascular mortality, acute coronary syndrome, target lesion revascularisation, stroke, or major bleeding. Data were analysed using Cox regression models, Kaplan–Meier estimator plots, and propensity score matching. Results: A total of 159 consecutive patients treated with DCB-only angioplasty and 222 consecutive patients treated with DES-only angioplasty were identified. The majority of the vessels treated were large vessels (>3 mm). After a median follow-up of 4 years, a total of 52 (33%) patients in the DCB and 73 (33%) patients in the DES group encountered a MACE (p = 0.97). The results did not change following propensity score matching. On multivariate Cox regression analysis in the propensity score-matched cohort, atrial fibrillation [HR = 2.37, CI: (1.22–4.61), p = 0.011] and diabetes [HR = 1.71, CI: (1.13–2.60), p = 0.011] were the only independent adverse predictors of MACE. Conclusions: DCB-only angioplasty appears to be safe and efficient when compared to DES for multivessel angioplasty in terms of MACEs after a follow-up of 4 years. Full article
(This article belongs to the Special Issue Current Trends and Future Challenges in Coronary Artery Disease)
►▼ Show Figures

Figure 1

Show export options expand_more Show export options expand_less
Select all
Export citation of selected articles as:
 
Displaying articles 1-1
Back to TopTop