Hidradenitis Suppurativa (HS): Research Advances in Pathogenesis, Diagnosis and Treatment
A special issue of Journal of Clinical Medicine (ISSN 2077-0383). This special issue belongs to the section "Dermatology".
Deadline for manuscript submissions: closed (20 November 2021) | Viewed by 13492
Special Issue Editor
Special Issue Information
Dear Colleagues,
Hidradenitis suppurativa (HS) is increasingly recognized as one of the main dermatological disorders in western countries affecting 1% of the general population, mainly vulnerable individuals with a low socioeconomic status. The diagnosis is far from simple, as dermatologists have to look for the presence of chronic and unremitting nodules, abscesses, and sinus tracts in skin folds as the only criteria to diagnose HS. To make the diagnosis even more difficult, most patients often conceal HS as typical malodorous lesions in genital areas are associated with strong feelings of shame. As a result, HS diagnosis takes, in median, 7 years to be made, the patients moved from one treatment to another without obtaining any improvement, thus losing faith in the medical follow-up and frequently falling in to depression and, in the most severe cases, suicidal attempts.
The situation does not improve after diagnosis is finally established. Poor knowledge of HS pathogenesis reflects the lack of an effective treatment. Most patients receive a first treatment combining analgesics and topical and systemic antibiotics with HS often mistaken for folliculitis. Some dermatologists prescribe sulfonamides, immunosuppressants or isotreonin, used to treat acne. Adalimumab (an anti-TNF-a) is currently used off-label for severe to moderate cases, although not all patients respond to the treatment. Medical treatments seldom result in a cure, and the aggravation of lesions often leads to surgical resection of the skin of affected areas.
Over the last few years, however, research into HS pathogenesis has sensibly increased, giving new hopes for a faster diagnosis and effective treatments. The present Special Issue aims to present the last findings in HS pathogenesis that can improve its diagnosis and treatment.
Dr. Michele Boniotto
Guest Editor
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Journal of Clinical Medicine is an international peer-reviewed open access semimonthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
Keywords
- hidradenitis suppurativa
- genetics
- omics
- hair follicle
- Th17
- neutrophils
- plasma cells
- biologics
Benefits of Publishing in a Special Issue
- Ease of navigation: Grouping papers by topic helps scholars navigate broad scope journals more efficiently.
- Greater discoverability: Special Issues support the reach and impact of scientific research. Articles in Special Issues are more discoverable and cited more frequently.
- Expansion of research network: Special Issues facilitate connections among authors, fostering scientific collaborations.
- External promotion: Articles in Special Issues are often promoted through the journal's social media, increasing their visibility.
- e-Book format: Special Issues with more than 10 articles can be published as dedicated e-books, ensuring wide and rapid dissemination.
Further information on MDPI's Special Issue polices can be found here.
