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Hip Replacement: Epidemiology and Patient Outcomes
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Hip Replacement: Epidemiology and Patient Outcomes

A special issue of Journal of Clinical Medicine (ISSN 2077-0383). This special issue belongs to the section "Orthopedics".

Deadline for manuscript submissions: closed (30 June 2022) | Viewed by 7446

Special Issue Editor

Dr. Ilana Ackerman

E-Mail Website
Guest Editor
School of Public Health and Preventive Medicine, Monash University, Melbourne, VIC 3004, Australia
Interests: epidemiology, health services research; joint replacement surgery; mixed-methods research; patient-reported outcome measures; rehabilitation

Special Issue Information

Dear Colleagues,

Hip replacement surgery is a well-established and cost-effective procedure that can improve pain, functioning and quality of life for many patients. Understanding the changing use of hip replacement surgery can assist with resource allocation and health workforce planning and inform models of care. Consideration of surgical outcomes (for example, through the use of validated patient-reported tools or other recognised indicators) provides an important feedback loop that can be used to improve clinical care and optimise surgical outcomes. 

This Special Issue will focus on the epidemiology and patient outcomes of elective hip replacement surgery in older and younger adults. Areas of interest include but are not limited to health economics, health services research, patient-reported outcome measures (PROMs), return-to-work outcomes, and weight-management issues, as they relate to hip replacement surgery. Papers on hip replacement surgery after non-surgical management programs are also welcomed, as are papers reporting COVID-related impacts on hip replacement provision. 

Submissions for this Special Issue may include original research articles (quantitative, qualitative and mixed-methods research designs) or systematic reviews.

Dr. Ilana Ackerman
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Journal of Clinical Medicine is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • epidemiology
  • health economics
  • health services research
  • hip arthroplasty
  • hip replacement
  • patient-reported outcomes
  • patient-reported outcome measures
  • weight management
  • work outcomes

Published Papers (3 papers)

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Research

11 pages, 772 KiB  
Article
Functional Outcomes Following Hip Replacement in Community-Dwelling Older Adults
by Yuanyuan Wang, Alice Owen, Angus Franks, Ilana Ackerman, Sharyn M. Fitzgerald, Susan Liew, Robyn L. Woods, Anita E. Wluka, John J. McNeil and Flavia M. Cicuttini
J. Clin. Med. 2022, 11(17), 5117; https://doi.org/10.3390/jcm11175117 - 30 Aug 2022
Cited by 1 | Viewed by 2242
Abstract
Uncertainty remains regarding the benefit of hip replacement in older adults in the context of age-related decline in physical function. This study aimed to examine the effect of hip replacement on functional outcomes and identify factors associated with clinically important improvement in physical [...] Read more.
Uncertainty remains regarding the benefit of hip replacement in older adults in the context of age-related decline in physical function. This study aimed to examine the effect of hip replacement on functional outcomes and identify factors associated with clinically important improvement in physical function postoperatively in community-dwelling older adults. This cohort study was performed within the ASPREE trial, with 698 participants receiving hip replacement and 677 age- and sex-matched controls without knee or hip replacement during the trial drawn from 16,703 Australian participants aged ≥70 years. Health status (physical and mental component summary [PCS and MCS]) was assessed annually using the SF-12. Participants receiving hip replacement had significantly lower pre- and post-replacement PCS scores compared with controls (p < 0.0001). There was significant improvement in PCS score following hip replacement (mean change 4.9, 95%CI 4.0–5.7) but no change in controls (0.01, 95%CI −0.7–0.7). Following hip replacement, 46.7% of participants experienced clinically important improvement in PCS score, while 15.5% experienced worsened PCS score. Participants experiencing improved postoperative PCS score had significantly lower PCS and higher MCS scores preoperatively. The degree of preoperative physical function impairment was a significant indicator of older people most likely to benefit from hip replacement surgery. Full article
(This article belongs to the Special Issue Hip Replacement: Epidemiology and Patient Outcomes)
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12 pages, 833 KiB  
Article
A Nomogram for Predicting Non-Response to Surgery One Year after Elective Total Hip Replacement
by Michelle M. Dowsey, Tim Spelman and Peter F. M. Choong
J. Clin. Med. 2022, 11(6), 1649; https://doi.org/10.3390/jcm11061649 - 16 Mar 2022
Cited by 2 | Viewed by 1712
Abstract
Background: Total hip replacement (THR) is a common and cost-effective procedure for end-stage osteoarthritis, but inappropriate utilization may be devaluing its true impact. The purpose of this study was to develop and test the internal validity of a prognostic algorithm for predicting the [...] Read more.
Background: Total hip replacement (THR) is a common and cost-effective procedure for end-stage osteoarthritis, but inappropriate utilization may be devaluing its true impact. The purpose of this study was to develop and test the internal validity of a prognostic algorithm for predicting the probability of non-response to THR surgery at 1 year. Methods: Analysis of outcome data extracted from an institutional registry of individuals (N = 2177) following elective THR performed between January 2012 and December 2019. OMERACT-OARSI responder criteria were applied to Western Ontario and McMaster Universities Arthritis Index (WOMAC) pain and function scores at pre- and 1 year post-THR, to determine non-response to surgery. Independent prognostic correlates of post-operative non-response observed in adjusted modelling were then used to develop a nomogram. Results: A total of 194 (8.9%) cases were deemed non-responders to THR. The degree of contribution (OR, 95% CI) of each explanatory factor to non-response on the nomogram was, morbid obesity (1.88, 1.16, 3.05), Kellgren–Lawrence grade <4 (1.89, 1.39, 2.56), WOMAC Global rating per 10 units (0.86, 0.79, 0.94) and the following co-morbidities: cerebrovascular disease (2.39, 1.33, 4.30), chronic pulmonary disease (1.64; 1.00, 2.71), connective tissue disease (1.99, 1.17, 3.39), diabetes (1.86, 1.26, 2.75) and liver disease (2.28, 0.99, 5.27). The concordance index for the nomogram was 0.70. Conclusion: We have developed a prognostic nomogram to calculate the probability of non-response to THR surgery. In doing so, we determined that both the probability of and predictive prognostic factors for non-response to THR differed from a previously developed nomogram for total knee replacement (TKR), confirming the benefit of designing decision support tools that are both condition and surgery site specific. Future external validation of the nomogram is required to confirm its generalisability. Full article
(This article belongs to the Special Issue Hip Replacement: Epidemiology and Patient Outcomes)
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15 pages, 930 KiB  
Article
Concordance among Swedish, German, Danish, and UK EQ-5D-3L Value Sets: Analyses of Patient-Reported Outcomes in the Swedish Hip Arthroplasty Register
by Fitsum Sebsibe Teni, Ola Rolfson, Jenny Berg, Reiner Leidl and Kristina Burström
J. Clin. Med. 2021, 10(18), 4205; https://doi.org/10.3390/jcm10184205 - 17 Sep 2021
Cited by 1 | Viewed by 2373
Abstract
Background: Application of different value sets to health-related quality of life (HRQoL) measured with the EQ-5D-3L may lead to different results due to differences in methods, perspectives, and countries used. Focusing on concordance, this study aimed at understanding the implications of applying [...] Read more.
Background: Application of different value sets to health-related quality of life (HRQoL) measured with the EQ-5D-3L may lead to different results due to differences in methods, perspectives, and countries used. Focusing on concordance, this study aimed at understanding the implications of applying EQ-5D-3L value sets from Sweden, Germany, Denmark, and the UK to evaluate HRQoL of patients undergoing total hip replacement (THR) in Sweden before and after surgery. Methods: We performed a longitudinal study of patients in the Swedish Hip Arthroplasty Register from preoperative stage to 1-year follow-up (n = 73,523) using data collected from 2008 to 2016. Eight EQ-5D-3L value sets from the four countries were compared based on a valuation method (visual analogue scale (VAS) or time trade-off (TTO)), perspective (experience-based or hypothetical), and country. Concordance among the value sets with patient-reported EQ VAS score was also assessed. Longitudinal changes in EQ-5D-3L index over the 1-year follow-up were compared across value sets by method, perspective, and country. Results: Value sets based on the same method and perspective showed higher concordance in EQ-5D-3L index at both measurement time points than other comparisons. In the comparisons by perspective, VAS value sets showed higher concordance than TTO value sets. The Swedish VAS and the Danish TTO value sets showed the highest levels of concordance with patient-reported EQ VAS scores. Generally, value sets based on the same method and perspective had the smallest mean differences between changes in EQ-5D-3L indices from preoperative to 1-year postoperative follow-up. Conclusion: Among THR patients value sets based on the same method and perspective, a direct transfer of results across countries could be meaningful. In cases of differences in methods and perspectives among value sets, transfer of value sets across settings would have to consider conversion through crosswalk. Full article
(This article belongs to the Special Issue Hip Replacement: Epidemiology and Patient Outcomes)
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