Advantages and Disadvantages of Intracytoplasmic Sperm Injection
A special issue of Journal of Clinical Medicine (ISSN 2077-0383). This special issue belongs to the section "Reproductive Medicine & Andrology".
Deadline for manuscript submissions: closed (15 October 2022) | Viewed by 11094
Special Issue Editors
Interests: infertility; gametes; in vitro fertilization; IVF; ICSI; embryology
Interests: reproduction; endometriosis; endometrium; IVF; embryo
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Intracytoplasmic sperm injection (ICSI) was introduced in the early 1990s as one of the most dramatic technological breakthroughs in assisted reproductive technology (ART). In recent decades, the birth of millions of children around the world has been possible thanks to this procedure that has gained increasing favor, both among specialists of in vitro fertilization (IVF) techniques and among infertile couples. Originally born as a technique for couples with severe male infertility factors, today the application of the ICSI technique far exceeds the standard IVF procedure and in some parts of the world it is the only technique currently used. In addition to the severe male factor, other indications for ART imply the preferential use of ICSI compared to standard IVF, including preimplantation genetic diagnosis (PGT-a), the use of cryopreserved oocytes or spermatozoa, the in vitro maturation of oocytes, and previous failures of standard IVF cycles. In many cases, however, ICSI is used even in the absence of these specific conditions.
The main reason for this “indication creep” of ICSI over standard IVF is probably to reduce the occurrence of total fertilization failure, which is significantly increased following conventional insemination and represents a condition of particular discomfort for both operators and couples. However, it must be recognized that current scientific evidence is not entirely in favor of the preferential use of ICSI both in terms of the effectiveness of the procedures and in terms of safety. To facilitate discussion on this topic, the Journal of Clinical Medicine calls for papers for a thematic Special Issue on the “Advantages and Disadvantages of Intracytoplasmic Sperm Injection”, to be guest edited by Dr. Paola Viganò and Dr. Alessio Paffoni.
Dr. Alessio Paffoni
Dr. Paola Viganò
Guest Editors
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Keywords
- ICSI
- IVF
- oligospermia
- total fertilization failure
- PGT-a
- oocyte
- sperm
- assisted reproductive technology
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