Biomaterials in Dentistry: Current Status and Advances

A special issue of Journal of Functional Biomaterials (ISSN 2079-4983). This special issue belongs to the section "Dental Biomaterials".

Deadline for manuscript submissions: 30 September 2025 | Viewed by 1703

Special Issue Editors


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Guest Editor
Department of Medicine, Surgery and Dentistry, Scuola Medica Salernitana, University of Salerno, 84126 Salerno, Italy
Interests: oral medicine and interconnected systemic disorders; oral microbiome, dysbiosis and interconnected systemic disorders; periodontology and implantology; applied technologies (disease prevention, teledentistry)
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Guest Editor
Department of Medicine, Surgery and Dentistry, University of Salerno, 84084 Baronissi, Italy
Interests: implant dentistry; oral surgery; bone reconstructive surgery; dental materials
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

We invite you to contribute research and review articles highlighting innovative approaches and essential findings in implant dentistry and peri-implant health.

This Special Issue will provide a comprehensive overview of the latest advances in biomaterials and biofabrication techniques in oral medicine, periodontology, and implant dentistry. By bringing together researchers and clinicians from different disciplines, we aim to foster collaboration and facilitate the translation of innovative research findings into clinical practice to ultimately improve patient care and outcomes in oral health and regenerative medicine.

Original research articles addressing the development and characterization of novel biomaterials for oral tissue engineering and regeneration; review articles summarizing the latest advances in biofabrication techniques and their applications in oral surgery, periodontology, and implantology; studies examining the use of stem cells and growth factors in conjunction with hydrogel scaffolds to promote tissue regeneration and osseointegration; prospects for the clinical implementation of hydrogel-based therapies and their impact on improving patient outcomes in oral medicine and implant dentistry; and investigations into the role of digital planning and additive manufacturing technologies in the customization of hydrogel scaffolds for patient-specific treatment approaches are welcomed.

Dr. Maria Pia Di Palo
Dr. Federica Di Spirito
Dr. Francesco Giordano
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Journal of Functional Biomaterials is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • hydrogel
  • biofabrication
  • collagen
  • stem cells
  • oral medicine
  • periodontology
  • implantology
  • oral surgery
  • biomaterials
  • digital planning
  • tissue engineering
  • tissue regeneration
  • osseointegration

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Related Special Issue

Published Papers (2 papers)

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Research

13 pages, 1296 KiB  
Article
Impact of Autoclaving on the Dimensional Stability of 3D-Printed Surgical Guides for Aesthetic Crown Lengthening
by Albert González-Barnadas, Anna Ribas-Garcia, Adrià Jorba-García, Rui Figueiredo, Eduard Valmaseda-Castellón and Octavi Camps-Font
J. Funct. Biomater. 2025, 16(8), 284; https://doi.org/10.3390/jfb16080284 - 2 Aug 2025
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Abstract
The aim of this study was to evaluate the impact of autoclaving on the dimensional stability of surgical guides (SGs) for aesthetic crown lengthening (ACL) using different resins/printing methods. Fifty SGs for ACL were printed using five different resin/printer combinations (FL, SR, ND, [...] Read more.
The aim of this study was to evaluate the impact of autoclaving on the dimensional stability of surgical guides (SGs) for aesthetic crown lengthening (ACL) using different resins/printing methods. Fifty SGs for ACL were printed using five different resin/printer combinations (FL, SR, ND, KS and VC). All the SGs were scanned before (T0) and after (T1) sterilization. Autoclaving was conducted at 134 °C during 4 min. The STL files of each SG at T0 and T1 were compared with the original design (TR). Dimensional stability was measured using trueness and precision. Deviations from TR to T1 were calculated in the three space axes and by measuring the area between three reference landmarks. At T0, the FL group showed the best trueness and precision, while the SR group performed significantly worse than the other groups. At T1, all the groups except VC exhibited significant dimensional alterations compared with T0. Also, VC showed the best trueness and precision values. All the groups had a significant deviation in at least one space axis, while only the SR group exhibited significant variations from T1 to TR in the area between the reference landmarks. Most of the evaluated resin/3D printer combinations suffered significant dimensional alterations after autoclaving. Full article
(This article belongs to the Special Issue Biomaterials in Dentistry: Current Status and Advances)
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15 pages, 3215 KiB  
Article
The Effect of Collagen Membrane Fixation with Pins on Buccal Bone Regeneration in Immediate Dental Implant Sites: A Preclinical Study in Dogs
by Yuma Hazama, Takahisa Iida, Niklaus P. Lang, Fernando M. Muñoz Guzon, Giovanna Iezzi, Daniele Botticelli and Shunsuke Baba
J. Funct. Biomater. 2025, 16(8), 281; https://doi.org/10.3390/jfb16080281 - 31 Jul 2025
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Abstract
Background: The role of collagen membrane fixation during guided bone regeneration (GBR) remains debatable, particularly in post-extraction sockets with buccal defects and concomitant immediate implant placement. This study evaluated whether or not fixation with titanium pins improved regenerative outcomes. Methods: Six adult Beagle [...] Read more.
Background: The role of collagen membrane fixation during guided bone regeneration (GBR) remains debatable, particularly in post-extraction sockets with buccal defects and concomitant immediate implant placement. This study evaluated whether or not fixation with titanium pins improved regenerative outcomes. Methods: Six adult Beagle dogs received bilateral extractions of the fourth mandibular premolars. An implant was immediately placed in both the distal alveoli, and standardized buccal bone defects (5 mm height, 3–2 mm width) were prepared. All defects were filled with a slowly resorbing equine xenograft and covered by a resorbable pericardium membrane. At the test sites, the membrane was apically fixed with pins, while no fixation was applied to the control sites. After 3 months of healing, histomorphometric analyses were performed. Results: The vertical bone gain of the buccal crest was 3.2 mm in the test sites (pin group) and 2.9 mm in the control sites (no-pin) (p > 0.754). No significant difference was found in terms of bone-to-implant contact (BIC). However, residual graft particles were located significantly more coronally in the pin group compared to the no-pin group (p = 0.021). Morphometric analyses revealed similar new bone formation within the groups, but with higher amounts of residual xenograft and soft tissue in the pin group. Conclusions: Membrane fixation did not significantly enhance vertical bone gain, and although the slightly higher regeneration in the pin group (3.2 mm vs. 2.9 mm) may hold clinical relevance in esthetically sensitive areas and osseointegration, it appeared to limit apical migration of the grafting material. Full article
(This article belongs to the Special Issue Biomaterials in Dentistry: Current Status and Advances)
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