Monoclonal Antibodies as Tools to Diagnose and Treat Fungal Infection
A special issue of Journal of Fungi (ISSN 2309-608X). This special issue belongs to the section "Fungal Pathogenesis and Disease Control".
Deadline for manuscript submissions: closed (15 June 2021) | Viewed by 15332
Special Issue Editors
Interests: mycology; microbiology; immunology
Special Issues, Collections and Topics in MDPI journals
Interests: medical mycology; parasite–host relationship; systemic and emerging mycoses
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Invasive fungal infections are severe and often lead to lethal diseases, and their diagnosis and treatment remains a challenging task. Monoclonal antibodies are highly specific tools that are commonly used to detect microbial pathogens. Their therapeutic application is most advanced in the field of cancer therapy.
Monoclonal antibodies enable fast and sensitive detection of fungal antigens in clinical specimen. A prominent example for this type of application is the detection of galactomannan, a carbohydrate antigen released during Aspergillus fumigatus infection. The therapeutic use of monoclonal antibodies against fungal pathogens has not yet reached clinical practice, however, a plethora of studies published in recent years has demonstrated that certain monoclonal antibodies have the potential to limit or even clear fungal infections.
This Special Issue focuses on studies in which monoclonal antibodies are used to establish new diagnostic applications to combat and eliminate fungal pathogens or to identify interesting antigens that might be useful in either kind of approach.
Prof. Dr. Frank Ebel
Prof. Dr. Carlos Pelleschi Taborda
Guest Editors
Manuscript Submission Information
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Keywords
- monoclonal antibodies
- diagnostics
- therapy
- antigens