Diagnosis of Human Pathogenic Fungi

Dear Colleagues,

Fungal pathogens can cause a range of diseases in humans and represent an increasing global public health concern. Superficial fungal infections, such as ringworm, athlete’s foot caused by dermatophytes, or thrush, and dandruff caused by other fungi, are common worldwide and affect 20% to 25% of the world's population. Fungal infections of the skin, hair and nails are among the most common ailments of humans, while it is estimated that 3 million adults worldwide are sensitive to fungal allergens that cause considerable lung-associated pathologies. Invasive fungal diseases are recognised as an increasing global burden in immunocompromised and other seriously ill populations, with more than 300 million people affected and more than 1.5 million deaths globally per year from these diseases. The most common causes of life-threatening fungal infections are Candida spp, Aspergillus, Cryptococcus spp., Mucorales, and Pneumocystis jirovecii. The diagnosis of fungal infection by conventional methods such as culture and microscopy remains the gold standard, but this is difficult in patients with invasive fungal infections. Prompt diagnosis of invasive fungal infections is challenging and mainly relies on the detection of diagnostics biomarkers. However, the accurate detection and identification of the causative agent and of antifungal resistance is critical for optimum patient outcomes.

Dr. Eleonora Dubljanin
Guest Editor

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• invasive fungal infections
• superficial fungal infections
• laboratory diagnosis of human mycosis
• fungal biomarkers
• candidiasis
• aspergillosis
• mucomycosis
• dermatomycosis