Yeast Genetics 2021

Dear Colleagues,

Yeast Saccharomyces cerevisiae is not only one of the most important industrial microorganisms but also a model organism for investigation of almost all biological processes in eukaryotes. This conventional yeast was the first eukariote to be successfully transformed with exogenous DNA. Due to efficient homologous recombination between transforming DNA and its genome, it is easy to precisely genetically modify this yeast, allowing the construction of both biotechnologically relevant strains and strains used in scientific research. On the other hand, there is a huge number of uncharacterized or poorly characterized nonconventional yeasts, and it is already known that at least some of them have certain advantages over conventional yeasts, such as efficient use of alternative carbon sources, higher resistance to growth and fermentation inhibitors, production of interesting metabolites, etc. However, in a great majority of these nonconventional yeasts, the construction of desired strains is not a routine procedure because molecular tools for precise modification of their genome have not been developed yet. Therefore, the focus of this Special Issue is on research on the genetics of conventional and nonconventional yeast, as well as development of molecular tools for targeted modification of yeasts genomes and construction of potentially biotechnologically relevant yeast strains.

Dr. Ivan-Kresimir Svetec
Guest Editor

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