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Personalized Medicine in Interventional Cardiology and Cardiac Surgery
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Personalized Medicine in Interventional Cardiology and Cardiac Surgery

A special issue of Journal of Personalized Medicine (ISSN 2075-4426). This special issue belongs to the section "Personalized Therapy and Drug Delivery".

Deadline for manuscript submissions: closed (10 February 2024) | Viewed by 2553

Special Issue Editor

Dr. Vincenzo Sucato

E-Mail Website
Guest Editor
Department of ProMISE, University Hospital Paolo Giaccone, University of Palermo, Palermo, Italy
Interests: cardiovascular disease; coronary artery disease; coronary microvascular dysfunction; percutaneous coronary intervention; cardiovascular prevention; hypercholesterolemia
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

The discovery of new techniques in interventional cardiology and the creation of new dedicated tools have allowed a personalized path in cardiovascular medicine to embroider a diagnostic-therapeutic offer on the individual characteristics of the patients. In coronary pathologies, coronary catheterization allows the characterization of atherosclerotic plaques and other coronary pathologies from a functional and hemodynamic point of view. The use of tools dedicated to the detection of trans-stenotic pressure gradients allows the operator to obtain invasive measurements for the evaluation of hemodynamic criticality such as: instantaneous wave free ratio (iFR) and fractional flow reserve (FFR). Intravascular ultrasound (IVUS) and optical coherence tomography (OCT) are intravascular imaging technologies, used in the cardiac catheterization laboratory for characterizing coronary pathology and optimizing the acute and longer-term clinical impact of percutaneous coronary intervention. Interventional cardiology has expanded its evidence into structural pathologies such: closure of interatrial and interventrciular defects and Patent Foramen Ovale (PFO), closure of the atrial appendage, and in valvular diseases and congenital heart disease of adult. In valvular pathologies, catheterization imposes itself as an alternative to heart surgery, depending on the clinical, anatomical characteristics and the operative risk. Transcatheter Aortic Valve Implantation (TAVI) interventions for the correction of aortic valve pathology, MITRACLIP for mitral regurgitation, Triclip for tricuspid regurgitation are low-risk interventions compared to traditional surgical techniques and offer the possibility of correction of valvular diseases and clinical improvement even in elderly patients or patients suffering from multiple pathologies.

In this Special Issue, we welcome original research and review articles regarding interventional cardiology and other personalized interventional therapies for cardiovascular diseases.

Dr. Vincenzo Sucato
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Journal of Personalized Medicine is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • coronary artery disease
  • chronic coronary syndrome
  • coronary microvascular dysfunction
  • intravascular imaging
  • acute coronary syndrome
  • functional assessment of coronary artery disease
  • complex and high-risk coronary intervention (CHIP)
  • transcatheter aortic valve implantation (TAVI)
  • MitraClip
  • paten foramen ovale (PFO)

Published Papers (2 papers)

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Research

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12 pages, 4447 KiB  
Article
Uncommon Carotid Artery Stenting Complications: A Series by Images
by Giuseppe Vadalà, Vincenzo Sucato, Francesco Costa, Fausto Castriota, Roberto Nerla, Giuseppe Roscitano, Antonio Giovanni Versace, Alfredo Ruggero Galassi and Antonio Micari
J. Pers. Med. 2024, 14(3), 250; https://doi.org/10.3390/jpm14030250 - 26 Feb 2024
Cited by 1 | Viewed by 1327
Abstract
Aims: To describe through emblematic images rare but clinically relevant carotid artery stenting complications that occurred at two high-volume centres for carotid artery stenting (CAS). Background: CAS is an alternative to carotid endarterectomy (CEA) for the treatment of carotid artery stenosis in patients [...] Read more.
Aims: To describe through emblematic images rare but clinically relevant carotid artery stenting complications that occurred at two high-volume centres for carotid artery stenting (CAS). Background: CAS is an alternative to carotid endarterectomy (CEA) for the treatment of carotid artery stenosis in patients judged to be at high risk for CEA. CAS complications range between 1 and 9% and are higher in older patients complaining of neurological symptoms at the time of presentation. Besides periprocedural or early-after-procedure stroke, which remains the true Achilles’ heel of CAS, other dramatic complications might compromise the clinical outcomes of this procedure. Methods: Five infrequent complications, out of more than 1000 CAS performed in the years 2016–2021, have been described. Results: Among CAS complications, acute carotid stent thrombosis, rescue retrieval of a disconnected distal cerebral embolic protection device, plaque prolapse after carotid stenting, cerebral hyperperfusion syndrome (CHS), and radial artery long sheath entrapment requiring surgical intervention were found to account for 0.3% of the total number of procedures performed by operators with high CAS volume. Conclusions: Unusual CAS complications may infrequently occur, even in hands of expert operators. To know how to deal with such complications might help interventionalists to improve CAS performance. Full article
(This article belongs to the Special Issue Personalized Medicine in Interventional Cardiology and Cardiac Surgery)
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Review

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15 pages, 1361 KiB  
Review
The Application of Precision Medicine in Structural Heart Diseases: A Step towards the Future
by Grigorios Chrysostomidis, Anastasios Apostolos, Amalia Papanikolaou, Konstantinos Konstantinou, Grigorios Tsigkas, Antigoni Koliopoulou and Themistokles Chamogeorgakis
J. Pers. Med. 2024, 14(4), 375; https://doi.org/10.3390/jpm14040375 - 30 Mar 2024
Viewed by 945
Abstract
The personalized applications of 3D printing in interventional cardiology and cardiac surgery represent a transformative paradigm in the management of structural heart diseases. This review underscores the pivotal role of 3D printing in enhancing procedural precision, from preoperative planning to procedural simulation, particularly [...] Read more.
The personalized applications of 3D printing in interventional cardiology and cardiac surgery represent a transformative paradigm in the management of structural heart diseases. This review underscores the pivotal role of 3D printing in enhancing procedural precision, from preoperative planning to procedural simulation, particularly in valvular heart diseases, such as aortic stenosis and mitral regurgitation. The ability to create patient-specific models contributes significantly to predicting and preventing complications like paravalvular leakage, ensuring optimal device selection, and improving outcomes. Additionally, 3D printing extends its impact beyond valvular diseases to tricuspid regurgitation and non-valvular structural heart conditions. The comprehensive synthesis of the existing literature presented here emphasizes the promising trajectory of individualized approaches facilitated by 3D printing, promising a future where tailored interventions based on precise anatomical considerations become standard practice in cardiovascular care. Full article
(This article belongs to the Special Issue Personalized Medicine in Interventional Cardiology and Cardiac Surgery)
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