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Citations	Article
363	A Review of the Role of Artificial Intelligence in Healthcare by Ahmed Al Kuwaiti, Khalid Nazer, Abdullah Al-Reedy, Shaher Al-Shehri, Afnan Al-Muhanna, Arun Vijay Subbarayalu, Dhoha Al Muhanna and Fahad A. Al-Muhanna
113	Brain Tumor Classification Using Meta-Heuristic Optimized Convolutional Neural Networks by Sarah Zuhair Kurdi, Mohammed Hasan Ali, Mustafa Musa Jaber, Tanzila Saba, Amjad Rehman and Robertas Damaševičius
92	Predicting the Onset of Diabetes with Machine Learning Methods by Chun-Yang Chou, Ding-Yang Hsu and Chun-Hung Chou
92	Advancing Patient Care: How Artificial Intelligence Is Transforming Healthcare by Diana Gina Poalelungi, Carmina Liana Musat, Ana Fulga, Marius Neagu, Anca Iulia Neagu, Alin Ionut Piraianu and Iuliu Fulga
84	Trans-Arterial Chemoembolization Plus Systemic Treatments for Hepatocellular Carcinoma: An Update by Alessandro Rizzo, Angela Dalia Ricci and Giovanni Brandi
83	Ethical Conundrums in the Application of Artificial Intelligence (AI) in Healthcare—A Scoping Review of Reviews by Sreenidhi Prakash, Jyotsna Needamangalam Balaji, Ashish Joshi and Krishna Mohan Surapaneni
77	Perception about Health Applications (Apps) in Smartphones towards Telemedicine during COVID-19: A Cross-Sectional Study by Lingala Kalyan Viswanath Reddy, Pallavi Madithati, Bayapa Reddy Narapureddy, Sahithya Ravali Ravula, Sunil Kumar Vaddamanu, Fahad Hussain Alhamoudi, Giuseppe Minervini and Saurabh Chaturvedi
74	Type 1 Diabetes Mellitus and Autoimmune Diseases: A Critical Review of the Association and the Application of Personalized Medicine by Mihaela Simona Popoviciu, Nirja Kaka, Yashendra Sethi, Neil Patel, Hitesh Chopra and Simona Cavalu
67	Multi-Target Mechanisms of Phytochemicals in Alzheimer’s Disease: Effects on Oxidative Stress, Neuroinflammation and Protein Aggregation by Javad Sharifi-Rad, Simona Rapposelli, Simona Sestito, Jesús Herrera-Bravo, Alejandra Arancibia-Diaz, Luis A. Salazar, Balakyz Yeskaliyeva, Ahmet Beyatli, Gerardo Leyva-Gómez, Carlos González-Contreras, Eda Sönmez Gürer, Miquel Martorell and Daniela Calina
64	The Penn Medicine BioBank: Towards a Genomics-Enabled Learning Healthcare System to Accelerate Precision Medicine in a Diverse Population by Anurag Verma, Scott M. Damrauer, Nawar Naseer, JoEllen Weaver, Colleen M. Kripke, Lindsay Guare, Giorgio Sirugo, Rachel L. Kember, Theodore G. Drivas, Scott M. Dudek, Yuki Bradford, Anastasia Lucas, Renae Judy, Shefali S. Verma, Emma Meagher, Katherine L. Nathanson, Michael Feldman, Marylyn D. Ritchie, Daniel J. Rader and For The Penn Medicine BioBank

Citations	Article
52	Ethical Implications of Chatbot Utilization in Nephrology by Oscar A. Garcia Valencia, Supawadee Suppadungsuk, Charat Thongprayoon, Jing Miao, Supawit Tangpanithandee, Iasmina M. Craici and Wisit Cheungpasitporn
48	miRNA-Based Technologies in Cancer Therapy by Maria Pagoni, Claudia Cava, Diamantis C. Sideris, Margaritis Avgeris, Vassilios Zoumpourlis, Ioannis Michalopoulos and Nikolaos Drakoulis
47	Digital Twins in Healthcare: Methodological Challenges and Opportunities by Charles Meijer, Hae-Won Uh and Said el Bouhaddani
46	Challenging ChatGPT 3.5 in Senology—An Assessment of Concordance with Breast Cancer Tumor Board Decision Making by Sebastian Griewing, Niklas Gremke, Uwe Wagner, Michael Lingenfelder, Sebastian Kuhn and Jelena Boekhoff
38	Microbiome Dynamics: A Paradigm Shift in Combatting Infectious Diseases by Mohamed Kamel, Sami Aleya, Majed Alsubih and Lotfi Aleya
36	Assessment of Quality and Readability of Information Provided by ChatGPT in Relation to Anterior Cruciate Ligament Injury by Stephen Fahy, Stephan Oehme, Danko Milinkovic, Tobias Jung and Benjamin Bartek
35	The Promise of Explainable AI in Digital Health for Precision Medicine: A Systematic Review by Ben Allen
34	Decrease in Sperm Parameters in the 21st Century: Obesity, Lifestyle, or Environmental Factors? An Updated Narrative Review by Romualdo Sciorio, Luca Tramontano, Mohammed Adel and Steven Fleming
33	Associations of BDNF/BDNF-AS SNPs with Depression, Schizophrenia, and Bipolar Disorder by Anton Shkundin and Angelos Halaris
32	The Application of Radiomics and AI to Molecular Imaging for Prostate Cancer by William Tapper, Gustavo Carneiro, Christos Mikropoulos, Spencer A. Thomas, Philip M. Evans and Stergios Boussios

Citations	Article
28	Digital Twins’ Advancements and Applications in Healthcare, Towards Precision Medicine by Konstantinos Papachristou, Paraskevi F. Katsakiori, Panagiotis Papadimitroulas, Lidia Strigari and George C. Kagadis
23	AI-Reinforced Wearable Sensors and Intelligent Point-of-Care Tests by Ghita Yammouri and Abdellatif Ait Lahcen
14	Dysfunctional High-Density Lipoprotein Cholesterol and Coronary Artery Disease: A Narrative Review by Cristina Madaudo, Giada Bono, Antonella Ortello, Giuseppe Astuti, Giulia Mingoia, Alfredo Ruggero Galassi and Vincenzo Sucato
12	Tooth Loss in Periodontitis Patients—A Risk Factor for Mild Cognitive Impairment: A Systematic Review and Meta—Analysis by Bhawna Agarwal, Maria Eleonora Bizzoca, Gennaro Musella, Danila De Vito, Lorenzo Lo Muzio, Andrea Ballini, Stefania Cantore and Flavio Pisani
12	A Novel CNN-Based Framework for Alzheimer’s Disease Detection Using EEG Spectrogram Representations by Konstantinos Stefanou, Katerina D. Tzimourta, Christos Bellos, Georgios Stergios, Konstantinos Markoglou, Emmanouil Gionanidis, Markos G. Tsipouras, Nikolaos Giannakeas, Alexandros T. Tzallas and Andreas Miltiadous
11	Artificial Intelligence-Driven Diagnostic Processes and Comprehensive Multimodal Models in Pain Medicine by Marco Cascella, Matteo L. G. Leoni, Mohammed Naveed Shariff and Giustino Varrassi
11	Artificial Intelligence and Advanced Technology in Glaucoma: A Review by Emanuele Tonti, Sofia Tonti, Flavia Mancini, Chiara Bonini, Leopoldo Spadea, Fabiana D’Esposito, Caterina Gagliano, Mutali Musa and Marco Zeppieri
9	The Role of Artificial Intelligence and Emerging Technologies in Advancing Total Hip Arthroplasty by Luca Andriollo, Aurelio Picchi, Giulio Iademarco, Andrea Fidanza, Loris Perticarini, Stefano Marco Paolo Rossi, Giandomenico Logroscino and Francesco Benazzo
9	A Talk with ChatGPT: The Role of Artificial Intelligence in Shaping the Future of Cardiology and Electrophysiology by Angelica Cersosimo, Elio Zito, Nicola Pierucci, Andrea Matteucci and Vincenzo Mirco La Fazia
8	The Future of Pharmacogenomics: Integrating Epigenetics, Nutrigenomics, and Beyond by Jeffrey A. Shaman

Citations	Article
9	A Talk with ChatGPT: The Role of Artificial Intelligence in Shaping the Future of Cardiology and Electrophysiology by Angelica Cersosimo, Elio Zito, Nicola Pierucci, Andrea Matteucci and Vincenzo Mirco La Fazia
3	Beyond Biomarkers: Machine Learning-Driven Multiomics for Personalized Medicine in Gastric Cancer by Dongheng Ma, Canfeng Fan, Tomoya Sano, Kyoka Kawabata, Hinano Nishikubo, Daiki Imanishi, Takashi Sakuma, Koji Maruo, Yurie Yamamoto, Tasuku Matsuoka and Masakazu Yashiro
3	Genetic Polymorphisms in Cytochrome P450 Enzymes Involved in Vitamin D Metabolism and the Vitamin D Receptor: Their Clinical Relevance by Yazun Jarrar, Ghayda’ Alhammadin and Su-Jun Lee
2	PD-L1/PD-1 Expression in the Treatment of Oral Squamous Cell Carcinoma and Oral Potentially Malignant Disorders: An Overview of Reviews by Huda Moutaz Asmael Al-Azzawi, Syed Ameer Hamza, Rita Paolini, Mathew Lim, Romeo Patini and Antonio Celentano
2	Genetic Predictors of Paxlovid Treatment Response: The Role of IFNAR2, OAS1, OAS3, and ACE2 in COVID-19 Clinical Course by Mykhailo Buchynskyi, Iryna Kamyshna, Iryna Halabitska, Pavlo Petakh, Valentyn Oksenych and Oleksandr Kamyshnyi
2	Radiological Assessment After Pancreaticoduodenectomy for a Precision Approach to Managing Complications: A Narrative Review by Fabrizio Urraro, Vittorio Patanè, Alfredo Clemente, Nicoletta Giordano, Damiano Caputo, Roberto Cammarata, Gianluca Costa and Alfonso Reginelli
2	Comparative Changes in Fecal Microbiome After Endoscopic Resection and Surgical Resection in Gastric Cancer Patients by Hochan Seo, Jae Yong Park, Hee Sang You, Beom Jin Kim and Jae Gyu Kim
2	Artificial Intelligence in the Assessment and Grading of Acne Vulgaris: A Systematic Review by Daniele Omar Traini, Gerardo Palmisano, Cristina Guerriero and Ketty Peris
2	Digital Twin Models in Atrial Fibrillation: Charting the Future of Precision Therapy? by Paschalis Karakasis, Antonios P. Antoniadis, Panagiotis Theofilis, Panayotis K. Vlachakis, Nikias Milaras, Dimitrios Patoulias, Theodoros Karamitsos and Nikolaos Fragakis
2	Presepsin: An Emerging Biomarker in the Management of Cardiometabolic Disorders by Dimitrios Kouroupis, Ioanna Zografou, Panagiotis Doukelis, Dimitrios Patoulias, Djordje S. Popovic, Paschalis Karakasis, Athina Pyrpasopoulou, Konstantinos Stavropoulos, Christodoulos Papadopoulos, Olga Giouleme, Kalliopi Kotsa, Michael Doumas and Theocharis Koufakis

Citations	Article
633	The Enhanced Permeability and Retention (EPR) Effect: The Significance of the Concept and Methods to Enhance Its Application by Jun Wu
475	Accuracy in Wrist-Worn, Sensor-Based Measurements of Heart Rate and Energy Expenditure in a Diverse Cohort by Anna Shcherbina, C. Mikael Mattsson, Daryl Waggott, Heidi Salisbury, Jeffrey W. Christle, Trevor Hastie, Matthew T. Wheeler and Euan A. Ashley
433	Recent Advances in Tumor Targeting via EPR Effect for Cancer Treatment by Md Abdus Subhan, Satya Siva Kishan Yalamarty, Nina Filipczak, Farzana Parveen and Vladimir P. Torchilin
408	Global Challenges to Public Health Care Systems during the COVID-19 Pandemic: A Review of Pandemic Measures and Problems by Roxana Filip, Roxana Gheorghita Puscaselu, Liliana Anchidin-Norocel, Mihai Dimian and Wesley K. Savage
363	A Review of the Role of Artificial Intelligence in Healthcare by Ahmed Al Kuwaiti, Khalid Nazer, Abdullah Al-Reedy, Shaher Al-Shehri, Afnan Al-Muhanna, Arun Vijay Subbarayalu, Dhoha Al Muhanna and Fahad A. Al-Muhanna
354	Digital Twins: From Personalised Medicine to Precision Public Health by Maged N. Kamel Boulos and Peng Zhang
324	Health 2050: The Realization of Personalized Medicine through Crowdsourcing, the Quantified Self, and the Participatory Biocitizen by Melanie Swan
308	Breast Cancer Treatments: Updates and New Challenges by Anna Burguin, Caroline Diorio and Francine Durocher
273	Applications of Machine Learning Predictive Models in the Chronic Disease Diagnosis by Gopi Battineni, Getu Gamo Sagaro, Nalini Chinatalapudi and Francesco Amenta
212	Gallstone Disease, Obesity and the Firmicutes/Bacteroidetes Ratio as a Possible Biomarker of Gut Dysbiosis by Irina N. Grigor’eva

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64943	Reversal of Autism Symptoms among Dizygotic Twins through a Personalized Lifestyle and Environmental Modification Approach: A Case Report and Review of the Literature by Christopher R. D’Adamo, Josephine L. Nelson, Sara N. Miller, Maria Rickert Hong, Elizabeth Lambert and Heather Tallman Ruhm
57001	A Review of the Role of Artificial Intelligence in Healthcare by Ahmed Al Kuwaiti, Khalid Nazer, Abdullah Al-Reedy, Shaher Al-Shehri, Afnan Al-Muhanna, Arun Vijay Subbarayalu, Dhoha Al Muhanna and Fahad A. Al-Muhanna
40330	Neuropsychiatric Manifestations of Mast Cell Activation Syndrome and Response to Mast-Cell-Directed Treatment: A Case Series by Leonard B. Weinstock, Renee M. Nelson and Svetlana Blitshteyn
36079	Effects of Red and Infrared Laser Therapy in Patients with Tinnitus: A Double-Blind, Clinical, Randomized Controlled Study Combining Light with Ultrasound, Drugs and Vacuum Therapy by Vitor Hugo Panhóca, Antônio Eduardo de Aquino Junior, Viviane Brocca de Souza, Simone Aparecida Ferreira, Lais Tatiane Ferreira, Karina Jullienne de Oliveira Souza, Patricia Eriko Tamae, Marcelo Saito Nogueira and Vanderlei Salvador Bagnato
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34347	Fenugreek and Its Effects on Muscle Performance: A Systematic Review by Waleed I. Albaker
23972	Type 1 Diabetes Mellitus and Autoimmune Diseases: A Critical Review of the Association and the Application of Personalized Medicine by Mihaela Simona Popoviciu, Nirja Kaka, Yashendra Sethi, Neil Patel, Hitesh Chopra and Simona Cavalu
23875	Management of Hyponatremia in Heart Failure: Practical Considerations by Victoriţa Şorodoc, Andreea Asaftei, Gabriela Puha, Alexandr Ceasovschih, Cătălina Lionte, Oana Sîrbu, Cristina Bologa, Raluca Ecaterina Haliga, Mihai Constantin, Adorata Elena Coman, Ovidiu Rusalim Petriș, Alexandra Stoica and Laurenţiu Şorodoc
22563	Ratings of the Effectiveness of 13 Therapeutic Diets for Autism Spectrum Disorder: Results of a National Survey by Julie S. Matthews and James B. Adams
22253	Long COVID Is Not a Functional Neurologic Disorder by Todd E. Davenport, Svetlana Blitshteyn, Nicola Clague-Baker, David Davies-Payne, Glenn J. Treisman and Sarah F. Tyson

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64943	Reversal of Autism Symptoms among Dizygotic Twins through a Personalized Lifestyle and Environmental Modification Approach: A Case Report and Review of the Literature by Christopher R. D’Adamo, Josephine L. Nelson, Sara N. Miller, Maria Rickert Hong, Elizabeth Lambert and Heather Tallman Ruhm
40330	Neuropsychiatric Manifestations of Mast Cell Activation Syndrome and Response to Mast-Cell-Directed Treatment: A Case Series by Leonard B. Weinstock, Renee M. Nelson and Svetlana Blitshteyn
34835	Vasopressin in Sepsis and Other Shock States: State of the Art by Raquel García-Álvarez and Rafael Arboleda-Salazar
22563	Ratings of the Effectiveness of 13 Therapeutic Diets for Autism Spectrum Disorder: Results of a National Survey by Julie S. Matthews and James B. Adams
22253	Long COVID Is Not a Functional Neurologic Disorder by Todd E. Davenport, Svetlana Blitshteyn, Nicola Clague-Baker, David Davies-Payne, Glenn J. Treisman and Sarah F. Tyson
19238	Diagnostic Approach to Elevated Liver Function Tests during Pregnancy: A Pragmatic Narrative Review by Elton Dajti, Angelo Bruni, Giovanni Barbara and Francesco Azzaroli
17185	Folate Receptor Alpha Autoantibodies in the Pediatric Acute-Onset Neuropsychiatric Syndrome (PANS) and Pediatric Autoimmune Neuropsychiatric Disorders Associated with Streptococcal Infections (PANDAS) Population by Lindsey Wells, Nancy O’Hara, Richard E. Frye, Neeshi Hullavard and Erica Smith
15701	Possible Role of Fibrinaloid Microclots in Postural Orthostatic Tachycardia Syndrome (POTS): Focus on Long COVID by Douglas B. Kell, Muhammed Asad Khan, Binita Kane, Gregory Y. H. Lip and Etheresia Pretorius
15057	*The Role of Uric Acid in Human Health: Insights from the Uricase* Gene by Youssef M. Roman**
13593	How Sex Hormones Affect Migraine: An Interdisciplinary Preclinical Research Panel Review by Frederick Godley III, John Meitzen, Hadas Nahman-Averbuch, Mary Angela O’Neal, David Yeomans, Nanette Santoro, Nina Riggins and Lars Edvinsson

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9823	Aggressive and Autoaggressive Behaviors in Patients with Autism Spectrum Disorder in Correlation with Middle Cerebral Artery Flow Velocity by Maciej Abakumow, Maciej Przybylski, Mariusz Słoma, Olga Markowska, Katarzyna Sowa, Przemysław Jaśkiewicz and Krzysztof Kowalczuk
9801	Early Detection of Mental Health Crises through Artificial-Intelligence-Powered Social Media Analysis: A Prospective Observational Study by Masab A. Mansoor and Kashif H. Ansari
9721	Point of View: A Holistic Four-Interface Conceptual Model for Personalizing Shock Resuscitation by Philippe Rola, Eduardo Kattan, Matthew T. Siuba, Korbin Haycock, Sara Crager, Rory Spiegel, Max Hockstein, Vimal Bhardwaj, Ashley Miller, Jon-Emile Kenny, Gustavo A. Ospina-Tascón and Glenn Hernandez
8390	Advances in mRNA LNP-Based Cancer Vaccines: Mechanisms, Formulation Aspects, Challenges, and Future Directions by Eslam Ramadan, Ali Ahmed and Youssef Wahib Naguib
7714	Biomarkers and Rehabilitation for Functional Neurological Disorder by Victor W. Mark
7049	Digital Twins’ Advancements and Applications in Healthcare, Towards Precision Medicine by Konstantinos Papachristou, Paraskevi F. Katsakiori, Panagiotis Papadimitroulas, Lidia Strigari and George C. Kagadis
6904	AI-Reinforced Wearable Sensors and Intelligent Point-of-Care Tests by Ghita Yammouri and Abdellatif Ait Lahcen
5573	Occlusion and Biomechanical Risk Factors in Implant-Supported Full-Arch Fixed Dental Prostheses—Narrative Review by Andrea Berzaghi, Tiziano Testori, Riccardo Scaini and Sergio Bortolini
5290	Exploring the Immunological Role of the Microbial Composition of the Appendix and the Associated Risks of Appendectomies by Tarequl Islam, Md Shahjalal Sagor, Noshin Tabassum Tamanna, Md Kamrul Islam Bappy, Danishuddin, Md Azizul Haque and Maximilian Lackner
5273	Concussion and the Autonomic, Immune, and Endocrine Systems: An Introduction to the Field and a Treatment Framework for Persisting Symptoms by Jon L. Pertab, Tricia L. Merkley, Holly Winiarski, Kelly M. J. Cramond and Alex J. Cramond

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9721	Point of View: A Holistic Four-Interface Conceptual Model for Personalizing Shock Resuscitation by Philippe Rola, Eduardo Kattan, Matthew T. Siuba, Korbin Haycock, Sara Crager, Rory Spiegel, Max Hockstein, Vimal Bhardwaj, Ashley Miller, Jon-Emile Kenny, Gustavo A. Ospina-Tascón and Glenn Hernandez
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5098	Redefining Non-Motor Symptoms in Parkinson’s Disease by Laura Peña-Zelayeta, Karen M. Delgado-Minjares, Marcos M. Villegas-Rojas, Karen León-Arcia, Alberto Santiago-Balmaseda, Jesús Andrade-Guerrero, Isaac Pérez-Segura, Emmanuel Ortega-Robles, Luis O. Soto-Rojas and Oscar Arias-Carrión
4890	Genetic and Regulatory Mechanisms of Comorbidity of Anxiety, Depression and ADHD: A GWAS Meta-Meta-Analysis Through the Lens of a System Biological and Pharmacogenomic Perspective in 18.5 M Subjects by Kai-Uwe Lewandrowski, Kenneth Blum, Alireza Sharafshah, Kyriaki Z. Thanos, Panayotis K. Thanos, Richa Zirath, Albert Pinhasov, Abdalla Bowirrat, Nicole Jafari, Foojan Zeine, Milan Makale, Colin Hanna, David Baron, Igor Elman, Edward J. Modestino, Rajendra D. Badgaiyan, Keerthy Sunder, Kevin T. Murphy, Ashim Gupta, Alex P. L. Lewandrowski, Rossano Kepler Alvim Fiorelli and Sergio Schmidt Show full author list Hide full author list
3667	The Exchange Breathing Method for Seizure Intervention: A Historical and Scientific Review of Epilepsy and Its Evolving Therapeutic Paradigms by Frederick Robert Carrick, Pamela Daniels, Stephen Pelletier, Sofia Prysmakova, Ahmed Hankir, Mahera Abdulrahman and Nouf Al-Rumaihi
3516	The Accuracy of ChatGPT-4o in Interpreting Chest and Abdominal X-Ray Images by Pietro G. Lacaita, Malik Galijasevic, Michael Swoboda, Leonhard Gruber, Yannick Scharll, Fabian Barbieri, Gerlig Widmann and Gudrun M. Feuchtner
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64943	Reversal of Autism Symptoms among Dizygotic Twins through a Personalized Lifestyle and Environmental Modification Approach: A Case Report and Review of the Literature by Christopher R. D’Adamo, Josephine L. Nelson, Sara N. Miller, Maria Rickert Hong, Elizabeth Lambert and Heather Tallman Ruhm
57001	A Review of the Role of Artificial Intelligence in Healthcare by Ahmed Al Kuwaiti, Khalid Nazer, Abdullah Al-Reedy, Shaher Al-Shehri, Afnan Al-Muhanna, Arun Vijay Subbarayalu, Dhoha Al Muhanna and Fahad A. Al-Muhanna
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34835	Vasopressin in Sepsis and Other Shock States: State of the Art by Raquel García-Álvarez and Rafael Arboleda-Salazar

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17979	A Review of the Role of Artificial Intelligence in Healthcare by Ahmed Al Kuwaiti, Khalid Nazer, Abdullah Al-Reedy, Shaher Al-Shehri, Afnan Al-Muhanna, Arun Vijay Subbarayalu, Dhoha Al Muhanna and Fahad A. Al-Muhanna
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6466	A Pathophysiological Approach to Spontaneous Orbital Meningoceles: Case Report and Systematic Review by Piergiorgio Gaudioso, Elia Biancoli, Veronica Battistuzzi, Stefano Concheri, Tommaso Saccardo, Sebastiano Franchella, Giacomo Contro, Stefano Taboni, Elisabetta Zanoletti, Francesco Causin, Lorena Nico, Joseph Domenico Gabrieli, Roberto Maroldi, Piero Nicolai and Marco Ferrari
5447	Management of Hyponatremia in Heart Failure: Practical Considerations by Victoriţa Şorodoc, Andreea Asaftei, Gabriela Puha, Alexandr Ceasovschih, Cătălina Lionte, Oana Sîrbu, Cristina Bologa, Raluca Ecaterina Haliga, Mihai Constantin, Adorata Elena Coman, Ovidiu Rusalim Petriș, Alexandra Stoica and Laurenţiu Şorodoc
4885	Reversal of Autism Symptoms among Dizygotic Twins through a Personalized Lifestyle and Environmental Modification Approach: A Case Report and Review of the Literature by Christopher R. D’Adamo, Josephine L. Nelson, Sara N. Miller, Maria Rickert Hong, Elizabeth Lambert and Heather Tallman Ruhm
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3469	From Sweet to Sour: SGLT-2-Inhibitor-Induced Euglycemic Diabetic Ketoacidosis by Andrijana Koceva and Nika Aleksandra Kravos Tramšek
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3377	Predicting the Onset of Diabetes with Machine Learning Methods by Chun-Yang Chou, Ding-Yang Hsu and Chun-Hung Chou

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7417	Vasopressin in Sepsis and Other Shock States: State of the Art by Raquel García-Álvarez and Rafael Arboleda-Salazar
6466	A Pathophysiological Approach to Spontaneous Orbital Meningoceles: Case Report and Systematic Review by Piergiorgio Gaudioso, Elia Biancoli, Veronica Battistuzzi, Stefano Concheri, Tommaso Saccardo, Sebastiano Franchella, Giacomo Contro, Stefano Taboni, Elisabetta Zanoletti, Francesco Causin, Lorena Nico, Joseph Domenico Gabrieli, Roberto Maroldi, Piero Nicolai and Marco Ferrari
4885	Reversal of Autism Symptoms among Dizygotic Twins through a Personalized Lifestyle and Environmental Modification Approach: A Case Report and Review of the Literature by Christopher R. D’Adamo, Josephine L. Nelson, Sara N. Miller, Maria Rickert Hong, Elizabeth Lambert and Heather Tallman Ruhm
3561	Challenges in Septic Shock: From New Hemodynamics to Blood Purification Therapies by Fernando Ramasco, Jesús Nieves-Alonso, Esther García-Villabona, Carmen Vallejo, Eduardo Kattan and Rosa Méndez
3469	From Sweet to Sour: SGLT-2-Inhibitor-Induced Euglycemic Diabetic Ketoacidosis by Andrijana Koceva and Nika Aleksandra Kravos Tramšek
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2716	Point of View: A Holistic Four-Interface Conceptual Model for Personalizing Shock Resuscitation by Philippe Rola, Eduardo Kattan, Matthew T. Siuba, Korbin Haycock, Sara Crager, Rory Spiegel, Max Hockstein, Vimal Bhardwaj, Ashley Miller, Jon-Emile Kenny, Gustavo A. Ospina-Tascón and Glenn Hernandez
2524	Breaking Barriers—The Intersection of AI and Assistive Technology in Autism Care: A Narrative Review by Antonio Iannone and Daniele Giansanti
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2499	Digital Twins in Healthcare: Methodological Challenges and Opportunities by Charles Meijer, Hae-Won Uh and Said el Bouhaddani

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2716	Point of View: A Holistic Four-Interface Conceptual Model for Personalizing Shock Resuscitation by Philippe Rola, Eduardo Kattan, Matthew T. Siuba, Korbin Haycock, Sara Crager, Rory Spiegel, Max Hockstein, Vimal Bhardwaj, Ashley Miller, Jon-Emile Kenny, Gustavo A. Ospina-Tascón and Glenn Hernandez
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1419	Digital Twins’ Advancements and Applications in Healthcare, Towards Precision Medicine by Konstantinos Papachristou, Paraskevi F. Katsakiori, Panagiotis Papadimitroulas, Lidia Strigari and George C. Kagadis
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1230	Advances in mRNA LNP-Based Cancer Vaccines: Mechanisms, Formulation Aspects, Challenges, and Future Directions by Eslam Ramadan, Ali Ahmed and Youssef Wahib Naguib
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2716	Point of View: A Holistic Four-Interface Conceptual Model for Personalizing Shock Resuscitation by Philippe Rola, Eduardo Kattan, Matthew T. Siuba, Korbin Haycock, Sara Crager, Rory Spiegel, Max Hockstein, Vimal Bhardwaj, Ashley Miller, Jon-Emile Kenny, Gustavo A. Ospina-Tascón and Glenn Hernandez
926	Genetic and Regulatory Mechanisms of Comorbidity of Anxiety, Depression and ADHD: A GWAS Meta-Meta-Analysis Through the Lens of a System Biological and Pharmacogenomic Perspective in 18.5 M Subjects by Kai-Uwe Lewandrowski, Kenneth Blum, Alireza Sharafshah, Kyriaki Z. Thanos, Panayotis K. Thanos, Richa Zirath, Albert Pinhasov, Abdalla Bowirrat, Nicole Jafari, Foojan Zeine, Milan Makale, Colin Hanna, David Baron, Igor Elman, Edward J. Modestino, Rajendra D. Badgaiyan, Keerthy Sunder, Kevin T. Murphy, Ashim Gupta, Alex P. L. Lewandrowski, Rossano Kepler Alvim Fiorelli and Sergio Schmidt Show full author list Hide full author list
594	Redefining Non-Motor Symptoms in Parkinson’s Disease by Laura Peña-Zelayeta, Karen M. Delgado-Minjares, Marcos M. Villegas-Rojas, Karen León-Arcia, Alberto Santiago-Balmaseda, Jesús Andrade-Guerrero, Isaac Pérez-Segura, Emmanuel Ortega-Robles, Luis O. Soto-Rojas and Oscar Arias-Carrión
588	Exploring the Immunological Role of the Microbial Composition of the Appendix and the Associated Risks of Appendectomies by Tarequl Islam, Md Shahjalal Sagor, Noshin Tabassum Tamanna, Md Kamrul Islam Bappy, Danishuddin, Md Azizul Haque and Maximilian Lackner
502	Dysregulation of Circadian Markers, HAT1 and Associated Epigenetic Proteins, and the Anti-Aging Protein KLOTHO in Placenta of Pregnant Women with Chronic Venous Disease by Oscar Fraile-Martinez, Cielo García-Montero, Tatiana Pekarek, Julia Bujan, Silvestra Barrena-Blázquez, Eva Manuela Pena-Burgos, Laura López-González, Leonel Pekarek, Raul Díaz-Pedrero, Juan A. De León-Luis, Coral Bravo, Melchor Álvarez-Mon, Miguel A. Saez, Natalio García-Honduvilla and Miguel A. Ortega
443	Reducing Postoperative Complications in High-Risk Breast Surgery Patients: A Preliminary Study on the Efficacy of NPWT Dressing by Raquel Diaz, Ilaria Baldelli, Letizia Cuniolo, Ludovico Ponzielli, Elisa Bertulla, Giada Marassi, Federica Murelli, Chiara Cornacchia, Francesca Depaoli, Cecilia Margarino, Chiara Boccardo, Marco Gipponi, Simonetta Franchelli, Marianna Pesce, Franco De Cian and Piero Fregatti
440	One-Stop Mitral Valve Transcatheter Edge-to-Edge Repair and Left Atrial Appendage Occlusion in Patients with Atrial Fibrillation and Mitral Regurgitation: A Systematic Review and Meta-Analysis by Konstantinos Pamporis, Dimitrios Tsiachris, Konstantinos Grigoriou, Paschalis Karakasis, Ioannis Doundoulakis, Panagiotis Theofilis, Panagiotis Kouvatsos, Athanasios Saplaouras, Athanasios Kordalis, Aikaterini-Eleftheria Karanikola, Panagiotis Antonios Goutis and Konstantinos Tsioufis
437	Artificial Intelligence Detection of Occlusive Myocardial Infarction from Electrocardiograms Interpreted as “Normal” by Conventional Algorithms by Shifa R. Karim, Hans C. Helseth, Peter O. Baker, Gabriel A. Keller, H. Pendell Meyers, Robert Herman and Stephen W. Smith
430	The Uncommon Phenomenon of Short QT Syndrome: A Scoping Review of the Literature by Aristi Boulmpou, Andreas Giannopoulos, Christodoulos Papadopoulos, Georgios Giannopoulos, Ioannis Papagiannis, Georgios Zormpas, Anastasia Keivanidou, Liana Fidani and Vassilios Vassilikos
425	Patient Experience with Intranasal Esketamine in Treatment-Resistant Depression: Insights from a Multicentric Italian Study (REAL-ESKperience) by Marco Di Nicola, Maria Pepe, Giacomo d’Andrea, Ilaria Marcelli, Mauro Pettorruso, Ileana Andriola, Stefano Barlati, Matteo Carminati, Carlo Ignazio Cattaneo, Massimo Clerici, Domenico De Berardis, Sergio De Filippis, Bernardo Dell’Osso, Giorgio Di Lorenzo, Giuseppe Maina, Mirko Manchia, Matteo Marcatili, Vassilis Martiadis, Cinzia Niolu, Antonino Petralia, Gianluca Rosso, Gianluca Serafini, Maria Salvina Signorelli, Tommaso Vannucchi, Matteo Vismara, Raffaella Zanardi, Antonio Vita, Gabriele Sani, Giovanni Martinotti and REAL-ESKperience Study Group Show full author list Hide full author list

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17979	A Review of the Role of Artificial Intelligence in Healthcare by Ahmed Al Kuwaiti, Khalid Nazer, Abdullah Al-Reedy, Shaher Al-Shehri, Afnan Al-Muhanna, Arun Vijay Subbarayalu, Dhoha Al Muhanna and Fahad A. Al-Muhanna
17037	Accuracy in Wrist-Worn, Sensor-Based Measurements of Heart Rate and Energy Expenditure in a Diverse Cohort by Anna Shcherbina, C. Mikael Mattsson, Daryl Waggott, Heidi Salisbury, Jeffrey W. Christle, Trevor Hastie, Matthew T. Wheeler and Euan A. Ashley
15820	Applications of Machine Learning Predictive Models in the Chronic Disease Diagnosis by Gopi Battineni, Getu Gamo Sagaro, Nalini Chinatalapudi and Francesco Amenta
15816	Global Challenges to Public Health Care Systems during the COVID-19 Pandemic: A Review of Pandemic Measures and Problems by Roxana Filip, Roxana Gheorghita Puscaselu, Liliana Anchidin-Norocel, Mihai Dimian and Wesley K. Savage
14849	Health 2050: The Realization of Personalized Medicine through Crowdsourcing, the Quantified Self, and the Participatory Biocitizen by Melanie Swan
13949	The Impact of Marijuana on Antidepressant Treatment in Adolescents: Clinical and Pharmacologic Considerations by Samuel E. Vaughn, Jeffrey R. Strawn, Ethan A. Poweleit, Mayur Sarangdhar and Laura B. Ramsey
11298	Digital Twins: From Personalised Medicine to Precision Public Health by Maged N. Kamel Boulos and Peng Zhang
10948	Breast Cancer Treatments: Updates and New Challenges by Anna Burguin, Caroline Diorio and Francine Durocher
10310	Infectious Disease Management through Point-of-Care Personalized Medicine Molecular Diagnostic Technologies by Luc Bissonnette and Michel G. Bergeron
10086	Aligning the Aligners: Comparison of RNA Sequencing Data Alignment and Gene Expression Quantification Tools for Clinical Breast Cancer Research by Isaac D. Raplee, Alexei V. Evsikov and Caralina Marín de Evsikova

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