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Journal of Personalized Medicine publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Chemotherapy and Hematopoietic Stem Cell Transplantation

edited by

Luisa Sisinni

submission deadline 15 Nov 2025 | Viewed by 164 | Submission Open

Keywords: hematopoietic stem cell transplantation; chemotherapy toxicity and conditioning regimens; graft-versus-host disease (GVHD) management; immunotherapy and cellular therapies

(This special issue belongs to the Section Regenerative Medicine and Therapeutics)

Ehealth, Telemedicine, and AI in the Precision Medicine Era

edited by

Mirella Veras

submission deadline 20 Nov 2025 | 4 articles | Viewed by 20772 | Submission Open

Keywords: digital health; artificial intelligence; telemedicine; telerehabilitation; E-health; precision medicine; remote monitoring; wearable devices; mobile health (mHealth); virtual health; health informatics; machine learning; predictive analytics; personalized medicine; health technology

(This special issue belongs to the Section Methodology, Drug and Device Discovery)

Neurodegenerative Diseases: Molecular Pathology and Personalized Treatment

edited by

Oscar Arias-Carrion

submission deadline 20 Nov 2025 | 2 articles | Viewed by 9848 | Submission Open

Keywords: neurodegeneration; molecular pathology; precision medicine; biomarkers; personalized therapeutics

(This special issue belongs to the Section Mechanisms of Diseases)

Skin Pathophysiology and Management

edited by

Mohamad Goldust

, Joanna Goldberg and Mahsa Babaei

submission deadline 20 Nov 2025 | 2 articles | Viewed by 8310 | Submission Open

Keywords: skin disease pathophysiology; skin disease diagnosis; skin disease treatment

(This special issue belongs to the Section Personalized Therapy in Clinical Medicine)

Liquid Biopsy in Lung Cancer: Innovations in Precision Oncology

edited by

Maria Paola Belfiore

and

Valerio Nardone

submission deadline 20 Nov 2025 | Viewed by 305 | Submission Open

Keywords: liquid biopsy; lung cancer; biomarkers; diagnosis; personalized treatment

(This special issue belongs to the Section Methodology, Drug and Device Discovery)

Precision Medicine in Gynecological Endoscopy: From Personalized Diagnosis to Tailored Surgical Interventions

edited by

Nikolaos Kathopoulis

, Dimitrios Zacharakis and

Athanasios Douligeris

submission deadline 25 Nov 2025 | 2 articles | Viewed by 5817 | Submission Open

Keywords: gynecological endoscopy; minimally invasive and robotic surgeries; personalized gynecological care; gynecological healthcare; personalized diagnosis; genomic profiling; real-time imaging; AI algorithms; biomarker identification

(This special issue belongs to the Section Personalized Therapy in Clinical Medicine)

Recent Advances in Bariatric Surgery

edited by

Maria Sofia

and Andrea Peri

submission deadline 25 Nov 2025 | 4 articles | Viewed by 4772 | Submission Open

Keywords: bariatric surgery; morbid obesity; sleeve gastrectomy; gastric bypass; emerging procedures; early outcomes; long-term results

(This special issue belongs to the Section Methodology, Drug and Device Discovery)

Personalized Medicine in Gynecology and Obstetrics

edited by

Mǎdǎlin Marius Margan

and

Florin Gorun

submission deadline 25 Nov 2025 | 1 articles | Viewed by 2302 | Submission Open

Keywords: personalized medicine; genetic screening; risk assessment for pregnancy complications; fetal health monitoring; pharmacogenomics; hormone therapy; genetic testing for cancer risk fertility treatments; endometriosis; fibroid management; preventive care and screening

(This special issue belongs to the Section Personalized Therapy and Drug Delivery)

Molecular Pathology in Cancer Research

edited by Maurizio Martini and Giuseppe Giuffré

submission deadline 25 Nov 2025 | 2 articles | Viewed by 1483 | Submission Open

Keywords: molecular pathology; diagnostic pathology; cancer diagnosis; biomarkers; targeted therapy; genomics

(This special issue belongs to the Section Personalized Therapy in Clinical Medicine)

Precision Medicine in Spine Surgery: Updates and Challenges

edited by Mark James Lambrechts

submission deadline 25 Nov 2025 | Viewed by 184 | Submission Open

Keywords: spine; orthopedic surgery; neurosurgery; precision; endoscopic spine; artificial disc replacement; spinal deformity; patient-specific alignment

(This special issue belongs to the Section Personalized Therapy in Clinical Medicine)

Computer-Assisted Diagnosis and Personalized Treatment of Fracture

edited by Juan Jiménez-Delgado

submission deadline 30 Nov 2025 | 2 articles | Viewed by 5082 | Submission Open

Keywords: fracture diagnosis; computer-assisted simulation; artificial intelligence in orthopedics; medical imaging advances; personalized fracture treatment; computational fracture analysis; surgical planning tools; virtual reality in orthopedics; forensic analysis of fractures; multiscale modeling of bone

(This special issue belongs to the Section Methodology, Drug and Device Discovery)

Clinical Advances and Innovations in Reconstructive and Plastic Surgery

edited by Laura Răducu

submission deadline 30 Nov 2025 | 3 articles | Viewed by 4419 | Submission Open

Keywords: plastic surgery; breast reconstruction; robotics; microsurgery; burns injury

(This special issue belongs to the Section Personalized Therapy in Clinical Medicine)

Role of Genetic Tools in Diagnosis and Personalized Treatment for Neurological Diseases

edited by Federica Scalia

submission deadline 30 Nov 2025 | 1 articles | Viewed by 2428 | Submission Open

Keywords: neurological disorders; molecular modeling; bioinformatics; genetic tools; genetic variants; omic technologies; DNA sequencing; newborn screening; therapeutic procedure; mechanism of action

(This special issue belongs to the Section Personalized Therapy and Drug Delivery)

Otolaryngology in Clinical Practice: The Necessity of Personalized Medicine

edited by Jerome Rene Lechien

submission deadline 30 Nov 2025 | 3 articles | Viewed by 2201 | Submission Open

Keywords: otolaryngology; otorhinolaryngology; artificial Intelligence; personalized Medicine; treatments

(This special issue belongs to the Section Personalized Therapy in Clinical Medicine)

Personalized Radiation Therapy for Cancers: Current Status and Future Perspectives

edited by Roberta Carbonara and

Alba Fiorentino

submission deadline 30 Nov 2025 | 2 articles | Viewed by 2130 | Submission Open

Keywords: personalized radiotherapy; personalized oncology; adaptive radiotherapy; stereotactic radiotherapy; re-irradiation; immuno-radiotherapy; tumor microenvironment and radiotherapy

(This special issue belongs to the Section Methodology, Drug and Device Discovery)

Epigenetics in Precision Medicine: From Mechanism to Therapy

edited by

Andrea Latini

and

Valerio Caputo

submission deadline 30 Nov 2025 | 1 articles | Viewed by 1860 | Submission Open

Keywords: epigenetics; precision medicine; methylation; histone modifications; non-coding RNA

(This special issue belongs to the Section Epigenetic Therapy)

Personalized Medicine in Gastrointestinal Surgical Oncology

edited by

Dae Hoon Kim

and Myoung-Won Son

submission deadline 30 Nov 2025 | 1 articles | Viewed by 1538 | Submission Open

Keywords: personalized medicine; gastrointestinal surgical oncology; laparoscopic surgery; robotic surgery; AI in surgery; multimodal treatment; clinical trials; oncological outcomes

(This special issue belongs to the Section Personalized Therapy in Clinical Medicine)

Personalized Pain Medicine: Biomarkers and New Therapeutic Frontiers

edited by Gustavo Fabregat-Cid

submission deadline 30 Nov 2025 | Viewed by 226 | Submission Open

Keywords: pain medicine; biomarkers; omics; neuroimaging; pain phenotyping

(This special issue belongs to the Section Personalized Therapy and Drug Delivery)

Artificial Intelligence in Personalized Management of Cardiovascular Diseases

edited by

Dominique J. Monlezun

submission deadline 30 Nov 2025 | Viewed by 204 | Submission Open

Keywords: artificial intelligence; cardiovascular disease; health determinants and outcomes; cost effectiveness; policy; ethics; and governance

(This special issue belongs to the Section Methodology, Drug and Device Discovery)

Acute Myeloid Leukemia: Current Progress and Future Directions

edited by

Valeria Visconte

and

Luca Guarnera

submission deadline 10 Dec 2025 | 1 articles | Viewed by 2314 | Submission Open

(This special issue belongs to the Section Personalized Therapy in Clinical Medicine)

Complications in Vascular Surgery: Current Updates and Perspectives

edited by

Yamume Tshomba

submission deadline 10 Dec 2025 | Viewed by 219 | Submission Open

Keywords: endoleak; visceral ischaemia; lower limb ischaemia; graft infection; aneurysm shrinkage; sac growing; transient ischemic attack; stroke; deep vein thrombosis; vascular injuries; embolization

(This special issue belongs to the Section Personalized Therapy in Clinical Medicine)

Advances in Oral Health: Innovative and Personalized Approaches

edited by

Eleftherios G. Kaklamanos

, Heleni Vastardis and

Miltiadis A. Makrygiannakis

submission deadline 15 Dec 2025 | 3 articles | Viewed by 4478 | Submission Open

Keywords: artificial intelligence; machine learning; genetics; orthodontics; pediatric dentistry; preventive dentistry; periodontology

(This special issue belongs to the Section Methodology, Drug and Device Discovery)

Personalized Medicine in Psychiatry: Challenges and Opportunities

edited by

Gniewko Więckiewicz

submission deadline 20 Dec 2025 | 9 articles | Viewed by 31104 | Submission Open

Keywords: psychiatry; personalized medicine; epidemiology; public health; addictions; schizophrenia; depression; mental health; precision psychiatry; treatment response; genetic factors; biomarkers; pharmacogenomics; behavioral interventions; comorbidity; substance abuse; neurobiology; psychiatric disorders; psychosocial factors; population health

(This special issue belongs to the Section Personalized Therapy and Drug Delivery)

Advancements in Neurosurgical Oncology: Bridging Neurosurgery and Cancer Neuroscience

edited by

Andres M. Alvarez-Pinzon

submission deadline 20 Dec 2025 | 1 articles | Viewed by 12450 | Submission Open

Keywords: neuro-oncology; cancer progression; neural mechanisms in cancer; brain tumors; neurological implications of cancer; cancer-induced neuropathy; neural stem cells and cancer; neuroinflammation in cancer; neuroimaging in oncology; cancer therapeutics and neurological safety

(This special issue belongs to the Section Personalized Therapy in Clinical Medicine)

Plastic Surgery: New Perspectives and Innovative Techniques

edited by Joseph M. Escandón and

Oscar Javier Manrique

submission deadline 20 Dec 2025 | 4 articles | Viewed by 4765 | Submission Open

Keywords: plastic surgery procedures; free tissue flaps; gender-affirmation surgery; reconstructive procedures; lymphedema; breast cancer; oncologic reconstruction; body contouring; regenerative medicine; stem cell therapy; aesthetic surgery

(This special issue belongs to the Section Regenerative Medicine and Therapeutics)

Integrating Mathematical Modeling and Data Analysis in Personalized Medical Research

edited by

Dorota Bielińska-Wąż

and

Piotr Wąż

submission deadline 20 Dec 2025 | 2 articles | Viewed by 2015 | Submission Open

Keywords: personalized medicine; health informatics; mathematical modeling; data analysis; bioinformatics; artificial intelligence; machine learning

(This special issue belongs to the Section Omics/Informatics)

Personalized Medicine in Dental and Oral Health

edited by

Liliana Georgeta Foia

and

Magda Ecaterina Antohe

submission deadline 25 Dec 2025 | 4 articles | Viewed by 18231 | Submission Open

Keywords: oral health; systemic context; personalized medicine; pharmacogenomics; caries pathology; diagnostics; clinical evaluation; paraclinical evaluation

(This special issue belongs to the Section Personalized Therapy in Clinical Medicine)

Laparoscopy, Perioperative Care and Complications in Surgery for Gastrointestinal Diseases

edited by Michał Kisielewski

submission deadline 25 Dec 2025 | 2 articles | Viewed by 4202 | Submission Open

Keywords: laparoscopy; perioperative care; colorectal surgery; minimally invasive surgery; upper digestive surgery; hepatobiliary surgery; postoperative complications

(This special issue belongs to the Section Personalized Therapy in Clinical Medicine)

Artificial Intelligence and Computational Approaches for Clinical Pharmacology and Drug Development

edited by Paraskevi F. Katsakiori and

Panagiotis Papadimitroulas

submission deadline 25 Dec 2025 | 1 articles | Viewed by 2320 | Submission Open

Keywords: personalized medicine; artificial intelligence; optimized therapies; computational models; drug development; clinical pharmacology; machine learning; radiopharmaceuticals; prediction models; digital healthcare

(This special issue belongs to the Section Pharmacogenetics)

Advancing Personalized Medicine: Targeting Oxidative Stress in Neurodegenerative Diseases

edited by Lucia Buccarello

submission deadline 25 Dec 2025 | 1 articles | Viewed by 1601 | Submission Open

Keywords: oxidative stress; neurodegeneration; biomarkers; neuroprotection; protein oxidation; neuroinflammation; protein degradation; personalized medicine; intracellular signaling; neuronal death

(This special issue belongs to the Section Mechanisms of Diseases)

Personalized Medicine in Otolaryngology: New Challenges and Future Perspectives

edited by Jerome Rene Lechien

submission deadline 25 Dec 2025 | 1 articles | Viewed by 779 | Submission Open

Keywords: otolaryngology; oral cancer; oncology; head and neck surgery; minimally invasive; laryngology; artificial intelligence; rhinology; ENT; personalized

(This special issue belongs to the Section Personalized Therapy in Clinical Medicine)

Targeted Therapy and Biomarkers for Solid Tumors

edited by Anca Zgură and

Rodica Maricela Anghel

submission deadline 25 Dec 2025 | Viewed by 389 | Submission Open

Keywords: targeted therapy; biomarkers; solid tumors; oncology; cancer immunology; oncology radiotherapy; personalized medicine; molecular targets; drug resistance; translational research

(This special issue belongs to the Section Mechanisms of Diseases)

Inflammatory Bowel Disease (IBD): Diagnosis and Personalized Treatment

edited by Abigail Raffner (formerly Basson)

submission deadline 25 Dec 2025 | Viewed by 288 | Submission Open

Keywords: inflammatory bowel disease; diagnostic tools; biomarkers; therapeutic strategies; molecular mechanisms; microbiome; genetic predispositions; environmental factors; personalized treatment

(This special issue belongs to the Section Personalized Therapy and Drug Delivery)

Personalized Diagnosis and Therapy in Renal Cell Carcinoma

edited by Antonio Nacchia

submission deadline 25 Dec 2025 | Viewed by 233 | Submission Open

Keywords: inflammation; kidney cancer; renal cell cancer; inflammatory markers

(This special issue belongs to the Section Personalized Therapy and Drug Delivery)

Personalized Medicine and Management of Gynecologic Cancer

edited by Hooman Soleymani majd and

Federico Ferrari

submission deadline 25 Dec 2025 | Viewed by 221 | Submission Open

Keywords: proteomic; genomic; biomarkers; precision medicine; molecular profiling; immunotherapy; gynecologic cancer

(This special issue belongs to the Section Personalized Therapy and Drug Delivery)

Personalized Plastic and Reconstructive Surgery: Challenges and Prospects

edited by Johnny Ionut Efanov and Alain Michel Danino

submission deadline 25 Dec 2025 | Viewed by 129 | Submission Open

Keywords: reconstructive surgery; plastic surgery; flaps reconstruction; breast reconstruction; 3D printing; personalized surgery; biomaterials; imaging-assisted surgery; robotics

(This special issue belongs to the Section Regenerative Medicine and Therapeutics)

Cancer Immunotherapy: Current Advancements and Future Perspectives

edited by

Stefano Forte

and

Gianluca Ferini

submission deadline 31 Dec 2025 | 7 articles | Viewed by 17999 | Submission Open

Keywords: personalized immunotherapy; molecular pathways in cancer immunotherapy; precision medicine; molecular markers; molecular bases of abscopal effect; sustained therapeutic response

(This special issue belongs to the Section Methodology, Drug and Device Discovery)

Obstetrics and Gynecology and Women's Health—2nd Edition

edited by

Panagiotis N. Tsikouras

submission deadline 31 Dec 2025 | 2 articles | Viewed by 16830 | Submission Open

Keywords: uterine fibroids; uterine myoma; leiomyoma; uterine artery embolization; endometriosis; gynecological surgery; infertility; endocrinology; hysteroscopy; hormonal therapies; personalized medicine

(This special issue belongs to the Section Sex, Gender and Hormone Based Medicine)

Advancing Personalized Spine Surgery Through Minimally Invasive Techniques—Perspectives from Inter-American Society for Minimally Invasive Spine Surgery (SICCMI)

edited by

Kai-Uwe Lewandrowski

submission deadline 31 Dec 2025 | 2 articles | Viewed by 9070 | Submission Open

Keywords: spine surgery; minimally invasive techniques; personalized care; personalized medicine; precision imaging; 3D printing in orthopedics; biomarkers in spinal health; artificial intelligence in surgery; robotics in spine surgery; genomics and spinal disorders; pain management and rehabilitation; surgical navigation systems; biocompatible materials for implants; patient-specific surgical planning; regenerative medicine in spine health; future trends in spinal surgery

(This special issue belongs to the Section Personalized Therapy in Clinical Medicine)

Clinical and Experimental Surgery in Personalized Molecular Medicine

edited by

Apostolos E. Papalois

and Manousos M. Konstadoulakis

submission deadline 31 Dec 2025 | 3 articles | Viewed by 7358 | Submission Open

Keywords: personalized molecular medicine; clinical practice; surgical research; surgical oncology; multidisciplinary approaches

(This special issue belongs to the Section Personalized Therapy in Clinical Medicine)

Recent Research on Personalized Approaches to Clinical Therapeutics and Medication Safety

edited by

Sheraz Ali

submission deadline 31 Dec 2025 | 2 articles | Viewed by 4461 | Submission Open

Keywords: clinical therapeutics; medication safety; pharmacotherapy; personalized medicine; treatment optimization; polypharmacy

(This special issue belongs to the Section Epidemiology)

Biomarkers and Pathogenesis of Infectious Diseases: From Research to Personalized Medicine

edited by

César Henríquez-Camacho

submission deadline 31 Dec 2025 | 2 articles | Viewed by 3527 | Submission Open

Keywords: biomarkers; infectious diseases; pathogenesis; personalized medicine

(This special issue belongs to the Section Disease Biomarkers)

Digital Pathology in Translational Medicine and Clinical Practice

edited by

Alessandro Caputo

Vincenzo L'Imperio

and Filippo Fraggetta

submission deadline 31 Dec 2025 | 1 articles | Viewed by 3235 | Submission Open

Keywords: digital pathology; computational pathology; integrative pathology; computer-aided diagnosis; artificial intelligence; biomarker discovery

(This special issue belongs to the Section Mechanisms of Diseases)

Personalized Approaches in Spinal Deformity: Innovations in Diagnosis and Treatment

edited by

Mitchell S. Fourman

submission deadline 31 Dec 2025 | 1 articles | Viewed by 1058 | Submission Open

Keywords: adult spinal deformity; preoperative planning; minimally invasive spine surgery; sagittal malalignment; patient-specific hardware; precision medicine; personalized treatment

(This special issue belongs to the Section Methodology, Drug and Device Discovery)

Advances in Transfusion Medicine and Immunological Research

edited by Luca Mele

submission deadline 31 Dec 2025 | Viewed by 354 | Submission Open

Keywords: transfusion medicine; immunological responses; blood safety; cellular therapy; alloimmunity

(This special issue belongs to the Section Mechanisms of Diseases)

Personalized Medicine in Platelet Disease

edited by

Tomas Jose Gonzalez-Lopez

submission deadline 31 Dec 2025 | Viewed by 220 | Submission Open

Keywords: personalized medicine; platelet-related pathologies; molecular biology; platelet dysfunction; molecular mechanisms; platelets

Personalized Medicine and Surgery in Cardiovascular Disorders

edited by

Quynh Nguyen

and Edward D. Percy

submission deadline 31 Dec 2025 | Viewed by 195 | Submission Open

Keywords: precision medicine; cardiovascular disorders; cardiogenetics; translational medicine; genomic and multi-omics approaches to cardiovascular diseases

(This special issue belongs to the Section Personalized Therapy and Drug Delivery)

Artificial Intelligence and Advanced Medical Imaging in Personalized Medicine

edited by Paul Andrei Ștefan and Diana Feier

submission deadline 31 Dec 2025 | Viewed by 162 | Submission Open

Keywords: artificial intelligence; medical imaging; personalized medicine; textural analysis; radiomics

(This special issue belongs to the Section Methodology, Drug and Device Discovery)

Innovative and Future Trends in Personalized Medicine for Retinal Diseases

edited by Joanna Dolar-Szczasny

submission deadline 31 Dec 2025 | Viewed by 129 | Submission Open

Keywords: retinal disease; age-related macular degeneration; diabetic retinopathy; gene therapy; retinal biomarker; personalized medicine; retinal imaging; molecular profile; artificial intelligence in ophthalmology; inherited retinal diseases

(This special issue belongs to the Section Personalized Therapy and Drug Delivery)

Personalized Treatments in Thoracic Oncology Surgery

edited by

Georg Schlachtenberger

and Alberto Lopez

submission deadline 10 Jan 2026 | 2 articles | Viewed by 2482 | Submission Open

Keywords: minimally invasive surgery; TNM classification; adjuvant treatment; long-term survival

(This special issue belongs to the Section Methodology, Drug and Device Discovery)

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