Special Issues

Journal of Personalized Medicine publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Application of Deep and Machine Learning in Personalized Medicine and Individualized Bioinstruments
edited by
submission deadline 25 Apr 2025 | 5 articles | Viewed by 22795 | Submission Open
Keywords: intelligent medical devices; wearable biosensors; AI; machine learning; deep learning; Personalized medicine
(This special issue belongs to the Section Omics/Informatics)
Current Updates into Personalized Medicine for Anesthesia, Emergency Medicine, Disaster Medicine, Mass Gathering Events
edited by and Fabio Guarracino
submission deadline 25 Apr 2025 | 2 articles | Viewed by 3266 | Submission Open
Keywords: hemodynamic monitoring; artificial intelligence for the prevention of hypotensive events; brain activity monitoring; artificial intelligence; multiparametric operating room monitoring; mass gathering events; disaster medicine; CBRN (chemical; biological; radiological; and nuclear); public health preparedness
(This special issue belongs to the Section Clinical Medicine, Cell, and Organism Physiology)
Biomarkers in Diagnosis and Treatment of Pulmonary Disease
edited by and Konstantinos Porpodis
submission deadline 25 Apr 2025 | 1 articles | Viewed by 2532 | Submission Open
Keywords: biomarkers; asthma; obstructive disease; cancer; pulmonary fibrosis; airway remodeling; inflammation
(This special issue belongs to the Section Disease Biomarker)
Novel Challenges and Advances in Pediatric Hematology and Hematologic Malignancies
edited by Katarzyna Pawińska-Wa̧sikowska
submission deadline 25 Apr 2025 | 1 articles | Viewed by 1522 | Submission Open
Keywords: pediatric hematology; hematology malignancies; therapies; diagnosis; immunotherapies; supportive care
(This special issue belongs to the Section Mechanisms of Diseases)
Personalized Medicine in Endometriosis
edited by Christine Bekos
submission deadline 25 Apr 2025 | Viewed by 488 | Submission Open
Keywords: microbiome; epigenetics; fatigue; laparoscopic surgery; lifestyle changes; endometriosis
(This special issue belongs to the Section Clinical Medicine, Cell, and Organism Physiology)
Neuroradiology and Neurosurgery: Current Updates and Clinical Challenges
edited by
submission deadline 25 Apr 2025 | Viewed by 216 | Submission Open
Keywords: neurosurgery; neuroradiology; neurooncology; neuroanatomy; neurology; glioma
(This special issue belongs to the Section Clinical Medicine, Cell, and Organism Physiology)
Advances in Emerging Technologies for Rehabilitation: Personalized Perspective submission deadline 30 Apr 2025 | 4 articles | Viewed by 8329 | Submission Open
Keywords: virtual reality; mixed reality; augmented reality; robotic interventions; exoskeletons; eHealth; mHealth; wearable technology; telerehabilitation; remote support; barriers and challenges of new technologies in rehabilitation; psychosocial effects of new technology interventions; insights in novel approaches in technology-supported rehabilitation; biometric technology; personalized perspective
(This special issue belongs to the Section Methodology, Drug and Device Discovery)
Diagnosis and Personalized Management of Endometriosis
edited by Elvira Bratila and
submission deadline 30 Apr 2025 | 1 articles | Viewed by 6268 | Submission Open
Keywords: endometriosis; pain; infertility; minimally invasive surgery; ultrasound; MRI; medical treatment
(This special issue belongs to the Section Personalized Therapy and Drug Delivery)
Application of Artificial Intelligence in Personalized Medicine: Diagnosis and Treatment
edited by Abdulkader Helwan
submission deadline 30 Apr 2025 | 2 articles | Viewed by 4285 | Submission Open
Keywords: artificial intelligence (AI); personalized medicine; precision health; AI-driven diagnostics; machine learning; deep learning; predictive analytics; genomics; proteomics; biomarkers; patient-centric care; treatment personalization; healthcare data integration; drug discovery; real-time monitoring; ethical considerations in AI; individual variability; wearable technology; health informatics
(This special issue belongs to the Section Methodology, Drug and Device Discovery)
Gene Expression in Personalized Management of Diseases of Civilization submission deadline 30 Apr 2025 | 1 articles | Viewed by 3437 | Submission Open
Keywords: gene expression; personalized medicine; precision medicine; diseases of civilisation; genomic technologies; next-generation sequencing; microarray analysis; molecular markers; biomarker validation; data integration; computational tools; tailored therapies; cancer; cardiovascular diseases; diabetes; neurodegenerative diseases; precision oncology; genomic profiling; therapeutic response prediction; disease management
(This special issue belongs to the Section Omics/Informatics)
Medical Imaging and Interventional Radiology: Current Updates and Clinical Challenges submission deadline 30 Apr 2025 | 1 articles | Viewed by 2926 | Submission Open
Keywords: interventional radiology; diagnostic imaging; computed tomography; diagnostic radiology; magnetic resonance; ultrasound imaging
(This special issue belongs to the Section Methodology, Drug and Device Discovery)
Precision Medicine in Neurooncology and Neurosurgery for the 21st Century, 2nd Edition
edited by and José Pedro Lavrador
submission deadline 30 Apr 2025 | 2 articles | Viewed by 2759 | Submission Open
Keywords: neurooncology; brain tumour/tumour; precision; personalized; glioma; brain mapping
(This special issue belongs to the Section Clinical Medicine, Cell, and Organism Physiology)
Clinical Progress in Personalized Management of Cardiac Surgery
edited by Chiara Tessari and Augusto D'Onofrio
submission deadline 30 Apr 2025 | 2 articles | Viewed by 1913 | Submission Open
Keywords: clinical and hemodynamic evaluation of heart valve bioprostheses and tissue engineering; clinical and hemodynamic evaluation of heart valve repair techniques; advanced heart failure and surgical treatment options; immunological evaluation in heart transplant patients; cardiovascular regenerative medicine; telemedicine and artificial intelligence application in cardiac surgery
(This special issue belongs to the Section Clinical Medicine, Cell, and Organism Physiology)
Clinical Diagnosis and Treatment in Otorhinolaryngology
edited by Delia Hînganu and Marius Valeriu Hînganu
submission deadline 30 Apr 2025 | Viewed by 440 | Submission Open
Keywords: ENT surgery; multimodality imaging; prevention; voice formation; middle ear pathology; inner ear pathology
(This special issue belongs to the Section Clinical Medicine, Cell, and Organism Physiology)
Diabetic Foot: New Devices and AI for Clinical Diagnosis and Therapies in Personalized Medicine submission deadline 30 Apr 2025 | Viewed by 427 | Submission Open
Keywords: diabetic foot ulcers; diabetic foot infections; diabetic foot mortality; diabetic foot treatment therapy; artificial intelligence; devices; diagnosis; personalized therapies; sensors; artificial intelligence; big data; data mining; data science; deep learning; machine learning; bioimage recognition; bioinformatics; neural network; biosignals
(This special issue belongs to the Section Methodology, Drug and Device Discovery)
Advances in Diagnostics and Management of Respiratory System Diseases
edited by and Chao-Tien Hsu
submission deadline 30 Apr 2025 | Viewed by 243 | Submission Open
Keywords: elderly; geriatric respiratory diseases; cardiovascular disease; metabolic disease; cancer
(This special issue belongs to the Section Clinical Medicine, Cell, and Organism Physiology)
Personalized Applications of Musculoskeletal Imaging
edited by Daniela Berritto and
submission deadline 30 Apr 2025 | Viewed by 215 | Submission Open
Keywords: musculoskeletal; artificial intelligence; ultra-high-frequency ultrasound; cone beam CT; low-field MRI  ; photoacoustic  ; advances
(This special issue belongs to the Section Methodology, Drug and Device Discovery)
Precision Medicine in the Intensive Care Unit
edited by Carmen Orban and
submission deadline 10 May 2025 | 1 articles | Viewed by 1581 | Submission Open
Keywords: critical care; phenotypes in the intensive care unit; personalized medicine; patient-centered management; organ dysfunction; organ support; advanced monitoring; diagnostics
(This special issue belongs to the Section Personalized Critical Care)
Novel and Personalized Treatment Concepts in Gynecologic Cancer—2nd Edition
edited by and
submission deadline 10 May 2025 | Viewed by 271 | Submission Open
Keywords: ovarian cancer; endometrial cancer; vulvar cancer; cervical cancer; homologous recombination; targeted therapy; DNA damage repair; biomarkers; imaging; individualized treatment
(This special issue belongs to the Section Clinical Medicine, Cell, and Organism Physiology)
Personalized Diagnosis and Personalized Therapy in Chronic Upper Aerodigestive Tract Disorders
edited by Maria Raffaella Marchese
submission deadline 15 May 2025 | 1 articles | Viewed by 2247 | Submission Open
Keywords: upper aerodigestive tract; swallowing; voice; rhinitis; sinonasal diseases; dysphonia; tonsillitis; peritonsillar abscess; OSAS; laryngopharyngeal reflux
(This special issue belongs to the Section Personalized Therapy and Drug Delivery)
Current Trends in Cataract Surgery
edited by Romina Fasciani and
submission deadline 15 May 2025 | 2 articles | Viewed by 2078 | Submission Open
Keywords: refractive cataract surgery; visual quality; dry eye; side effects; advanced technology intraocular lenses; AMD IOLs
(This special issue belongs to the Section Methodology, Drug and Device Discovery)
New Trends and Challenges in Digital Dentistry
edited by and Flares Baratto-Filho
submission deadline 15 May 2025 | Viewed by 246 | Submission Open
Keywords: dental research; tomography; radiograph; artificial inteligence; machine learning; digital dentistry
(This special issue belongs to the Section Methodology, Drug and Device Discovery)
Tailoring Treatment with Biomarkers: Advancements in Heart Failure Management submission deadline 16 May 2025 | 2 articles | Viewed by 3831 | Submission Open
Keywords: biomarkers; heart failure; precision cardiology; risk prediction; outcomes; treatment
(This special issue belongs to the Section Disease Biomarker)
Diabetes Mellitus: Current Research and Future Perspectives, 2nd Edition
edited by
submission deadline 20 May 2025 | 4 articles | Viewed by 6584 | Submission Open
Keywords: diabetes treatment; drug metabolism; disease complications; polymorphisms; epigenetics; metabolomics; proteomics
(This special issue belongs to the Section Mechanisms of Diseases)
Breast Cancer: Current Trends and Future Challenges in Evaluation and Treatment
edited by Stefano Spinaci and Giulia Ferrarazzo
submission deadline 20 May 2025 | 2 articles | Viewed by 2930 | Submission Open
Keywords: breast cancer; breast surgery; conservative surgery; robotic breast techniques; male breast cancer
(This special issue belongs to the Section Clinical Medicine, Cell, and Organism Physiology)
Personalized Therapeutics and Drug Development of Liver Disease submission deadline 20 May 2025 | Viewed by 189 | Submission Open
Keywords: precision medicine; hepatocellular carcinoma (hcc); non-alcoholic fatty liver disease (nafld); metabolic dysfunction-associated steatotic liver disease (masld); liver fibrosis; biomarkers; targeted therapy; drug development; pharmacogenomics; immunotherapy; molecular pathways; genomic profiling; personalized treatment; translational research; clinical trials; novel therapeutics; liver disease management; drug delivery systems
(This special issue belongs to the Section Personalized Therapy and Drug Delivery)
Sex and Gender-Related Issues in the Era of Personalized Medicine
edited by , Anna Maria Moretti and Biagio Moretti
submission deadline 22 May 2025 | 7 articles | Viewed by 12683 | Submission Open
Keywords: gender; sex differences; sex factors; personalized medicine; cardiovascular disease; hypertension; obesity; diabetes; psychiatry and psychology; public health and epidemiology; women’ s health; sex; osteoporosis; osteoarthritis; musculoskeletal diseases
(This special issue belongs to the Section Sex, Gender and Hormone Based Medicine)
Innovations in Personalized Diagnosis and Treatment for Cystic Fibrosis
edited by
submission deadline 22 May 2025 | Viewed by 313 | Submission Open
Keywords: cystic fibrosis; CFTR mutations; modulators; biomarkers; treatment strategies; theratyping; genotype– phenotype correlation; pharmacogenomics; gene therapy; disease modeling; precision medicine; personalized diagnostics and therapies
(This special issue belongs to the Section Clinical Medicine, Cell, and Organism Physiology)
Emergency Medicine: Clinical Advances and Challenges in Diagnosis and Treatment, 2nd Edition submission deadline 25 May 2025 | 10 articles | Viewed by 18990 | Submission Open
Keywords: shock and resuscitation; sepsis; learning; critical patient approach; medical education; challenging diagnosis; treatment advances; use of simulation in medical training; emergency department digitalization; interesting cases in emergency medicine; diagnostic and therapeutic protocols in emergency medicine
(This special issue belongs to the Section Personalized Critical Care)
Personalized Medicine for Autism Spectrum Disorder
edited by
submission deadline 25 May 2025 | 1 articles | Viewed by 9984 | Submission Open
Keywords: autism spectrum disorder; comorbidity; personalized medicine; environmental factors; diagnosis; classification; treatment; management
(This special issue belongs to the Section Personalized Therapy and Drug Delivery)
Precision Medicine in Vascular Disease
edited by Gaetano Lanza and Carlo Setacci
submission deadline 25 May 2025 | 4 articles | Viewed by 6811 | Submission Open
Keywords: precision medicine; vascular diseases; pathogenetics; diagnostics; genetics; omics; biomarkers; predictive factors; medical therapies; surgical indications
(This special issue belongs to the Section Clinical Medicine, Cell, and Organism Physiology)
Clinical Advances in Dermatology: Pathophysiology, Diagnosis and Treatment
edited by and Manuel Galán-Gutiérrez
submission deadline 25 May 2025 | 3 articles | Viewed by 4912 | Submission Open
Keywords: psoriasis; atopic dermatitis; laser therapy; urticaria; alopecia areata; treatment; biological treatment; JAK (Janus Kinase) inhibitors
(This special issue belongs to the Section Clinical Medicine, Cell, and Organism Physiology)
The Gut Microbiome as a Target for the Treatment of Inflammatory Bowel Diseases
edited by and
submission deadline 25 May 2025 | 1 articles | Viewed by 4210 | Submission Open
Keywords: inflammatory bowel diseases (IBD); gut microbiome; microbial dysbiosis; Crohn's disease; ulcerative colitis; microbiota; microbiome– host interactions; immune response; microbial metabolites; fecal microbiota transplantation (FMT); probiotics; prebiotics; postbiotics; precision medicine; personalized therapy; microbial biomarkers; microbiome-based interventions; microbiome modulation; mucosal healing; gut– brain axis; microbiome analysis techniques; clinical trials; translational research; microbial engineering; therapeutic targets; metabolomics
(This special issue belongs to the Section Disease Biomarker)
Urological Cancer: Clinical Advances in Personalized Therapy
edited by and Marco Paciotti
submission deadline 25 May 2025 | 1 articles | Viewed by 1751 | Submission Open
Keywords: minimally invasive surgery; robot-assisted surgery; immunotherapy; prostate cancer; renal cancer; urothelial cancer
(This special issue belongs to the Section Personalized Therapy and Drug Delivery)
Precision Medicine in Cardiovascular Disease
edited by
submission deadline 25 May 2025 | Viewed by 578 | Submission Open
Keywords: cardiovascular disease; personalized medicine  ; genomics; risk prediction  ; precision therapy  ; AI; telediagnostics  ; telemedicine
(This special issue belongs to the Section Clinical Medicine, Cell, and Organism Physiology)
Pediatric Neurology: Current Trends, Rehabilitation and Future Challenges, 2nd Edition
edited by
submission deadline 25 May 2025 | Viewed by 491 | Submission Open
Keywords: neurodevelopmental disorders; cerebral palsy; autism; assessment; sleep
(This special issue belongs to the Section Clinical Medicine, Cell, and Organism Physiology)
Novel Biomarkers and Personalized Diagnosis in Neurodegenerative Disease
edited by Edoardo Gioele Spinelli
submission deadline 25 May 2025 | Viewed by 451 | Submission Open
Keywords: Alzheimer’ s disease; dementia; amyotrophic lateral sclerosis; Parkinson’ s disease; neurodegeneration; neuroimaging; MRI; biomarkers; artificial intelligence; machine learning
(This special issue belongs to the Section Methodology, Drug and Device Discovery)
Personalized Medicine of Obesity and Metabolic Disorders
edited by , and Cătălina Poiană
submission deadline 25 May 2025 | Viewed by 302 | Submission Open
Keywords: obesity; childhood obesity; metabolic disorders; leptin; adipogenesis; adipokines; dietary intake; physical activity; behavior; obesity-related diseases; metabolic dysfunction-associated steatotic liver disease (MASLD)
(This special issue belongs to the Section Clinical Medicine, Cell, and Organism Physiology)
Diagnostic and Interventional Radiology: Opportunities and Challenges of Advanced Imaging Techniques
edited by Leona S. Alizadeh and Boris Bodelle
submission deadline 25 May 2025 | Viewed by 265 | Submission Open
Keywords: advanced imaging techniques; diagnostic radiology; interventional radiology; personalized medicine; precision diagnosis; minimally invasive procedures; image-guided therapy; artificial intelligence in radiology; cardiovascular imaging; oncology imaging
(This special issue belongs to the Section Methodology, Drug and Device Discovery)
Cancer Immunology: New Advances in Personalized Therapies
edited by John Victor Napoleon
submission deadline 25 May 2025 | Viewed by 252 | Submission Open
Keywords: personalized therapy; immune system modulation; drugs and pharmaceutics; checkpoint inhibitor therapy; cancer immunotherapy; targeted drug delivery; tumor microenvironment; treatment resistance; combination therapy
(This special issue belongs to the Section Personalized Therapy and Drug Delivery)
Innovations in Cancer Immunology: Personalized Therapeutic Approaches
edited by
submission deadline 25 May 2025 | 1 articles | Viewed by 194 | Submission Open
Keywords: cancer immunology; personalized therapies; immunotherapy; CAR-T cell therapy; tumor microenvironment; biomarkers; patient selection; treatment resistance; combination therapies
(This special issue belongs to the Section Personalized Therapy and Drug Delivery)
Novel Therapeutic Approaches in Oral and Maxillofacial Surgery
edited by Krzysztof Dowgierd
submission deadline 25 May 2025 | Viewed by 188 | Submission Open
Keywords: craniofacial deformities; craniofacial reconstruction; cleft lip and palate; craniofacial biology; maxillofacial surgery
(This special issue belongs to the Section Mechanisms of Diseases)
Brain Tumor Microenvironment and Host Role: Implications for Immunotherapy
edited by Susobhan Sarkar
submission deadline 25 May 2025 | Viewed by 150 | Submission Open
Keywords: brain metastasis; brain tumor; glioma; microenvironment; microglia; immunotherapy; tumor microenvironment
(This special issue belongs to the Section Mechanisms of Diseases)
Advancements in Cognitive Neurosciences for Personalized Medicine
edited by Antonio Gennaro Nicotera
submission deadline 30 May 2025 | 3 articles | Viewed by 5041 | Submission Open
Keywords: cognitive neuroscience; pediatric neurology; neuropsychology; neurogenetic; neurocomputation; autism; epilepsy
(This special issue belongs to the Section Clinical Medicine, Cell, and Organism Physiology)
Selected Papers From the pHealth 2024 Conference, Rende, Italy, 27–29 May 2024
edited by , and Pierangelo Veltri
submission deadline 30 May 2025 | 1 articles | Viewed by 1274 | Submission Open
Keywords: 5P medicine; transformed health ecosystems; systems integration and interoperability; knowledge representation and management
(This special issue belongs to the Section Omics/Informatics)
New Insights into Personalized Medicine for Cardiac Surgery: Clinical Advances in Diagnosis, Treatment, and Prognosis
edited by and Anja Osswald
submission deadline 30 May 2025 | 1 articles | Viewed by 864 | Submission Open
Keywords: cardiovascular disease; patient-centered care; personalized medicine; interdisciplinary approaches; artificial intelligence; prognostic tools; minimally invasive surgery; robotic surgery; bioengineering; cardiovascular genomics
(This special issue belongs to the Section Clinical Medicine, Cell, and Organism Physiology)
Machine Learning in Epidemiology
edited by Xingyu Zhang and
submission deadline 30 May 2025 | Viewed by 417 | Submission Open
Keywords: artificial intelligence; machine learning; epidemiology; predictive analytics; health data; public health; precision medicine; disease surveillance; big data analytics
(This special issue belongs to the Section Epidemiology)
Cardiology and Vascular Health: Pathophysiology, Therapeutics and Epidemiology submission deadline 31 May 2025 | 5 articles | Viewed by 13068 | Submission Open
Keywords: cardiovascular disease; peripheral arterial disease; coronary heart disease; heart failure; cerebrovascular diesease; diabetes mellitus; dyslipidemia; arterial hypertension; arterial stiffness; endothelial dysfunction
(This special issue belongs to the Section Clinical Medicine, Cell, and Organism Physiology)
Personalized Medicine in Ophthalmology: Diagnosis, Prevention, and Treatment
edited by Antonio Di Zazzo and
submission deadline 31 May 2025 | 1 articles | Viewed by 2669 | Submission Open
Keywords: ocular surface; dry eye disease; scleral lenses; corneal disease; keratoconus
(This special issue belongs to the Section Personalized Therapy and Drug Delivery)
Challenges and Opportunities in Personalized Management of Bone and Joint Infections submission deadline 31 May 2025 | 1 articles | Viewed by 2327 | Submission Open
Keywords: bone and joint infections; prosthetic joint infection; arthroplasty infection; definition of prosthetic joint infection; prosthetic joint infection prevention; diagnosis of prosthetic joint infection; prosthetic joint infection management; antimicrobial therapy of prosthetic joint infection; diagnostics and management of septic arthritis in native joints; future research directions for improved patient outcomes
(This special issue belongs to the Section Clinical Medicine, Cell, and Organism Physiology)
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